The U.S. Government Represented by The Department of Veterans Affairs Patent applications |
Patent application number | Title | Published |
20160106331 | FRACTAL INDEX ANALYSIS OF HUMAN ELECTROENCEPHALOGRAM SIGNALS - A system and method for Multifractal-Detrended Fluctuation Analysis (MF-DFA) on digitized Human EEG signals is presented. A list of Hurst exponents, or Hurst exponent spectrum (“h” values) are generated, and multifractal singularity spectrum indices (“D(h)” values) produce a graph that approximates an inverted parabola. The output multifractal DFA spectrum is able to represent key features of the internal neuronal dynamics for the cortical neurons underlying the scalp-placed electrode which records the signals. | 04-21-2016 |
20150273053 | Methods to enhance T-cell mediated immune response - The present invention provides methods for restoring or enhancing T cell mediated immune response in individuals of middle and advanced age. | 10-01-2015 |
20110281932 | Methods to enhance T-cell mediated immune response - The present invention provides methods for restoring or enhancing T cell mediated immune response in individuals of middle and advanced age. | 11-17-2011 |
20110212854 | METHODS AND COMPOSITIONS FOR DIAGNOSIS, STRATIFICATION, AND MONITORING OF ALZHEIMER'S DISEASE AND OTHER NEUROLOGICAL DISORDERS IN BODY FLUIDS - The inventors have discovered a collection of proteinaceous biomarkers (“AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative disorders, particularly Alzheimer's disease and mild cognitive impairment (MCI). The invention further provides methods of identifying candidate agents for the treatment of Alzheimer's disease by testing prospective agents for activity in modulating AD biomarker levels. | 09-01-2011 |
20110117100 | COMPOSITIONS AND METHODS FOR DIAGNOSIS, STRATIFICATION AND TREATMENT OF AMYLOIDOGENIC DISEASES - Natural human autoantibodies against toxic assemblies of Aβ and related peptide species offer a unique immune repertoire. Based on this repertoire, the present invention provides compositions and methods for diagnosis as well as for prophylactic and therapeutic treatment of neurodegenerative diseases such as Alzheimer's disease that are characterized by accumulation of beta-amyloid deposits. The same human autoantibodies may be useful for prophylactic and therapeutic treatment of other neurodegenerative disorders and systemic pathological conditions that are due to or are associated with toxic assemblies of other amyloidogenic peptides or proteins. | 05-19-2011 |
20080280819 | METHODS FOR PROMOTING HAIR GROWTH - This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure. | 11-13-2008 |