| The University of Washington through its Center for Commercialization, a public institution of Patent applications |
| Patent application number | Title | Published |
|---|
| 20120020965 | Molecules that bind CD180, compositions and methods of use - The present invention provides novel CD180 binding molecules, methods for their identification, and methods for their use. | 01-26-2012 |
| 20110306025 | Ultrasound Training and Testing System with Multi-Modality Transducer Tracking - An apparatus and a method reproduce a diagnostic or interventional procedure that is performed by medical personnel using ultrasound imaging. A simulator of ultrasound imaging is used for purposes such as training medical professionals, evaluating their competence in performing ultrasound-related procedures, and maintaining, refreshing, or updating those skills over time. | 12-15-2011 |
| 20110269937 | Conserved-Element Vaccines and Methods for Designing Conserved-Element Vaccines - Embodiments of the present invention include conserved-element vaccines and methods for designing and producing conserved-element vaccines. A conserved-element vaccine (“CEVac”) is a recombinant and/or synthetic vaccine that incorporates only highly conserved epitopes from an observed set of pathogen variants. The conserved epitopes are identified computationally by aligning biopolymer sequences, such as concatenated polypeptide sequences that together represent a pathogen proteome, corresponding to an observed set of pathogen variants, and computationally selecting conserved subsequences according to a number of subsequence-selection criteria. These subsequence-selection criteria may include a minimum conserved-subsequence length, a threshold frequency of occurrence of a particular monomer at each conserved, single-monomer position within a conserved subsequence, a threshold combined occurrence for a set of allowable variant monomers at a particular conserved, variable position within a conserved subsequence, and a maximum number of variable positions within a subsequence. A set of conserved subsequences identified according to the subsequence-selection criteria are then filtered to remove subsequences identical to, or too similar to, naturally-occurring host subsequences, and are then assembled into expression vectors for incorporation into microbial hosts for biosynthesis of a recombinant CEVac or assembled into one or more synthetic constructs for a synthetic CEVac. | 11-03-2011 |
