| The University of Vermont and State Agriculture College Patent applications |
| Patent application number | Title | Published |
| 20120009590 | DEVICE AND NON-TOXIC COMPOSITIONS AND METHODS FOR PERMEABILIZATION OF DROSOPHILA EMBRYOS - The invention provides compositions and methods for permeabilizing insect embryos by removing the waxy layer of the shell using a solution containing a non-toxic cyclic terpene and a non-toxic surfactant, preferably a non-ionic surfactant. The invention further provides kits to practice the method of the invention. The invention also provides methods for toxicology and other high throughput screening method including the compositions and methods of embryo permeabilization provided herein. | 01-12-2012 |
| 20110305673 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR - The invention features compositions comprising mesenchymal stem cells or multipotent stromal cells, agents secreted by such cells in culture, and methods featuring such cells for the repair or regeneration of a damaged tissue or organ. The present invention is based, at least in part, on the discovery that agents secreted by bone marrow mesenchymal stem cells or multipotent stromal cells (MSCs) were useful for the treatment or prevention of tissue damage related to ischemic injury (e.g., cerebral or cardiac ischemia). | 12-15-2011 |
| 20090298103 | Predicting hemostatic risk; dependence on plasma composition - Featured are methods for assessing hemostatic risk including the risk for ACS. Such methods include acquiring blood/plasma composition based on a biological sample obtained from a subject, determining parameters associated with blood clotting, simulating in silico blood clotting using the determined parameters and comparing the results of such simulation to a reference and to determine the hemostatic risk from said comparing. In further embodiments, such methods further include selecting a treatment regime or protocol based on the results of such comparing. In yet further embodiments, such methods further include assessing the efficacy of medicants, drugs and the like of a given treatment protocol such as by simulating in silico the application of such medicants, drugs and the like. | 12-03-2009 |
| 20090287089 | Methods, devices and apparatus for imaging for reconstructing a 3-D image of an area of interest - Featured are methods, devices and apparatuses for imaging tissue, such as cardiac tissue, using any of a number of imaging techniques (e.g., ultrasonic imaging techniques) and a 3-D tracking system. In embodiments, such methods, devices and apparatuses are configured so that a 3-D image can be reconstructed from image data acquired at different locations from the image data and three dimensional coordinates that are determined for each location whereat the imaging device was located. | 11-19-2009 |
| 20090215070 | Highly Sensitive Immunoassays and Antibodies for Detection of Blood Factor VIII - Disclosed are antibodies that selectively bind to blood coagulation factor FVIII, and highly sensitive immunological assays comprising these antibodies. Preferred assays can detect FVIII at about 3500-fold below the normal physiological levels, and have a wide array of applications including accurate monitoring of FVIII concentration in pharmaceutical products for treatment of blood coagulation disorders, and determination of FVIII levels in plasma of human patients, including those with blood coagulation disorders such as hemophilia. | 08-27-2009 |
| 20090202513 | RIBONUCLEASE AND THIAZOLIDINEDIONE COMPOUNDS AND THEIR USE IN METHODS TO TREAT CANCER - The present invention relates to methods and kits for the treatment of cancer. A novel drug combination comprising a ribonuclease compound and a thiazolidinedione compound has been identified as producing a synergistic cytotoxicity effect in cancer cells. Methods and kits pertaining to the co-administration of these compounds are discussed herein. | 08-13-2009 |