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The University of Utah Research Foundation

Salt Lake City, UT US

The University of Utah Research Foundation Patent applications
Patent application numberTitlePublished
20120081668IMAGING OF MACULAR PIGMENT DISTRIBUTIONS - Macular pigments are measured by spectrally selective lipofuscin detection. Light from a light source that emits light at a selected range of wavelengths that overlap the absorption band of macular carotenoids is directed onto macular tissue of an eye for which macular pigment levels are to be measured. Emitted light is then collected from the macular tissue. The collected light is filtered so that the collected light includes lipofuscin emission from the macular tissue at an excitation wavelength that lies outside the macular pigment absorption range and outside the excitation range of interfering fluorophores. The collected light is quantified at each of a plurality of locations in the macular tissue and the macular pigment levels in the macular tissue are determined from the differing lipofuscin emission intensities in the macula and peripheral retina.04-05-2012
20120041305LIGHT-EMITTING DYE FOR INTRAOPERATIVE IMAGING OR SENTINEL LYMPH NODE BIOPSY - The present invention relates generally to the field of fluorescent dyes as a system useful for surgery imaging. More particularly, the present invention relates to systems, methods and kits for exciting fluorescent, phosphorescent or luminescent molecules with light from a light source and detecting the relative fluorescent, phosphorescent, or luminescent light intensity emitted from the fluorescent, phosphorescent, or luminescent molecule. Such systems may be applied as mapping agents for various surgical techniques, such as for cancer surgeries and biopsies.02-16-2012
20110298802MESH FORMATION FOR MULTI-ELEMENT VOLUMES - A method of forming mesh data for three-dimensional (3-D) data is provided. Inside/outside (IO) functions are generated based on indicator functions to identify element interfaces between a plurality of elements identified in the 3-D data. An indicator function is defined to represent a volume identified for an element within the 3-D data. A cell indicator function is defined for each element interface based on the IO functions to identify a plurality of types of element interfaces. The cell indicator function identifies points in the 3-D data where a plurality of the generated IO functions evaluate to approximately zero. The types of element interfaces are identified based on a number of elements that coincide at a point in the 3-D data. 3-D point locations are distributed on the identified element interfaces based on the plurality of types of element interfaces and the IO functions. Surface mesh data is generated based on the distributed 3-D point locations.12-08-2011
20110276915AUTOMATED DEVELOPMENT OF DATA PROCESSING RESULTS - A method of automatically completing a workflow is provided. An indicator of a partial workflow is received in a computing device. The partial workflow includes a module configured to process data. A workflow completion is determined for the partial workflow based on the partial workflow and a plurality of workflows stored in a computer-readable medium. The workflow completion is configured to further process the data. A workflow is presented in a display operably coupled to the computing device. The workflow includes the determined workflow completion and the partial workflow.11-10-2011
20110238323SYSTEMS AND METHODS FOR AUTOMATED MELTING CURVE ANALYSIS - An experimental melting curve is modeled as a sum of a true melting curve and background fluorescence. A deviation function may be generated based upon the experimental melting curve data and a model of a background signal. The deviation function may be generated by segmenting a range of the experimental curve into a plurality of windows. Within each window, a fit between the model of the background signal and the experimental melting curve data may be calculated. The deviation function may be formed from the resulting fit parameters. The deviation function may include background signal compensation and, as such, may be used in various melting curve analysis operations, such as data visualization, clustering, genotyping, scanning, negative sample removal, and the like. The deviation function may be used to seed an automated background correction process. A background-corrected melting curve may be further processed to remove an aggregation signal.09-29-2011
20110217212DISINFECTING CAPS HAVING AN EXTENDABLE FEATURE AND RELATED SYSTEMS AND METHODS - Some assemblies can include a male cap and a female cap, each of which can be used to cover separated medical connectors. In certain arrangements, a male cap can include a movable carriage that transitions from a retracted position when an assembly with which the male cap is associated is in a closed state to an extended position when the assembly is in an open state.09-08-2011
20110215275METHODS USING SURFACTANTS TO CONTROL UNINTENTIONAL DOPANT IN SEMICONDUCTORS - The use of surfactants that do not themselves act as dopants and are isoelectronic with either the group III or group V host atoms during OMVPE growth significantly reduces the incorporation of background impurities such as carbon, oxygen, sulfur and/or silicon. For example, the use of the surfactants Sb or Bi significantly reduces the incorporation of background impurities such as carbon, oxygen, sulfur and/or silicon during the OMVPE growth of III/V semiconductor materials, for example GaAs, GaInP, and GaP layers. As a result, an effective method for controlling the incorporation of impurity atoms is adding a minute amount of surfactant during OMVPE growth.09-08-2011
20110213341DISINFECTING CAPS HAVING SEALING FEATURES AND RELATED SYSTEMS AND METHODS - Caps can be used to cover and disinfect medical connectors. Some caps can create a seal with the medical connectors to prevent antiseptic from entering a fluid paths defined by a connector. Support members can aid in creating or maintaining the seal.09-01-2011
20110168551Nanopore Electrode, Nanopore Membrane, Methods of Preparation and Surface Modification, and Use Thereof - Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate.07-14-2011
20110166322ALPHA-CONOTOXIN PEPTIDES - The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.07-07-2011
20110044850DISINFECTING CAPS AND SYSTEMS AND ASSOCIATED METHODS - Caps can be used to cover and disinfect a male protrusion portion of a medical connector. Some caps can create a seal with the male protrusion to prevent antiseptic from entering a lumen the protrusion. A biasing element can aid in creating or maintaining the seal.02-24-2011
20100194237MEMS DEVICES AND SYSTEMS ACTUATED BY AN ENERGY FIELD - A microelectromechanical system (MEMS) device includes an actuator having a plurality of charge collection elements. At least one of the charge collection elements is configured to build up electrical charges by directly interacting with an energy field thereby actuating the MEMS through Coulombic interactions. An actuator for a MEMS device is configured to actuate the MEMS device through Coulombic interactions by pumping charges to the actuator when subject to an energy field. A method of actuating a MEMS device includes irradiating an actuator of the MEMS device with an energy field thereby building up electrical charges on the actuator, and actuating the MEMS device with Coulomb forces from the built up electrical charges.08-05-2010
20100145011ALPHA-CONOTOXIN PEPTIDES - The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.06-10-2010
20100049170STERILIZATION CAPS AND SYSTEMS AND ASSOCIATED METHODS - Caps can be used to cover and sterilize the male luer of a medical connector. Some caps can create a seal with the male luer to prevent antiseptic from entering a lumen of the male luer. A biasing element can aid in creating or maintaining the seal.02-25-2010
20100047123STERILIZATION CAPS AND SYSTEMS AND ASSOCIATED METHODS - One or more caps can be used to cover and sterilize one or more separated medical connectors. A pair of caps can be connected to each other and sealed when in a pre-use state. The paired caps can be unsealed so as to permit connection to the medical connectors.02-25-2010
20100021888Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes - Provided are compositions, methods and uses for identifying persons at an increased risk of infection by, transmission of, or accelerated progression of a disease caused by an HIV-1 virus. Diagnostic, prognostic and combined therapeutic kits are also provided.01-28-2010

Patent applications by The University of Utah Research Foundation