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THE UNIVERSITY OF NOTTINGHAM

THE UNIVERSITY OF NOTTINGHAM Patent applications
Patent application numberTitlePublished
20120115964XANTHAN GUM AND SWELLABLE PARTICULATE CONTAINING COMPOSITION AND USES THEREOF - This invention relates to a composition comprising at least about 0.2% w/w xanthan gum and at least about 6% w/w of a swellable particulate, and to uses thereof.05-10-2012
20120100174COMPOSITION COMPRISING SORTASE ANCHORED SURFACE PROTEINS OF STREPTOCOCCUS UBERIS - The present invention provides an immunogenic composition comprising one or more 04-26-2012
20120016475DEGRADABLE COMPOSITE - The invention relates to degradable composites and their use in biomedical implants, in particular the repair of damaged bones and/or cartilage.01-19-2012
20110311488MODIFIED BACTERIAL CELL - We describe modified bacterial cells that are defective in gene expression and their use in the treatment of bacterial infections of animals and plants and the inhibition of bacterial biofilm formation.12-22-2011
20110294119NOVEL METHODS OF DIFFERENTIATING YEAST STRAINS AND/OR DETERMINING GENETIC STABILITY OF YEAST STRAINS, AND USES THEREOF - The invention relates to a method of determining the strain or strains of yeast in a sample, comprising: obtaining and screening nucleic acid from yeast for target sequences comprises all or part of a gene, or a flanking region associated with a gene, in the yeast mitochondrial DNA; and determining from the results of the screen the yeast strain or strains in the sample. Also provided is a method of determining the genetic stability of a yeast strain in a sample, wherein one target sequences in the nucleic acid comprises all or part of a gene, or a flanking region associated with a gene, in the yeast mitochondrial DNA or all or part of a gene, or a flanking region associated with a gene, located in the subtelomeric region of a chromosome; and determining from the results of the screen if the yeast strain is genetically stable.12-01-2011
20110277553SPECIMEN CREEP TEST AND METHODS OF USING SUCH TESTS - A method for testing the mechanical properties of a specimen having a first contact surface and a second contact surface spaced apart and opposing the first contact surface, the method comprising: applying forces to the contact surfaces of the specimen to deform the specimen over a period of time and determining the response of the specimen to the forces over time; and defining a spatial distance between the contact surfaces such that the equivalent gauge length of the specimen is greater than the distance between the contact surfaces.11-17-2011
20110237677Inhibitors - The invention relates to inhibitors of tissue transglutaminase II activity and their use as a tocolytic agent.09-29-2011
20110169275POWER GENERATION - A power generating system 07-14-2011
20110162827HEAT EXCHANGER ARRANGEMENT - Heat exchangers can be utilised in thermo-acoustic engines to facilitate through acoustic oscillations electrical power generation via linear alternators and/or cooling effects. Provision of a heat exchanger arrangement 07-07-2011
20110092490PYRIMIDINES, TRIAZINES AND THEIR USE AS PHARMACEUTICAL AGENTS - A compound of formula (I) and its pharmaceutically acceptable salts or solvates and physiologically hydrolysable, solubilising or immobilisable derivatives wherein: Ar is a 5-membered heteroaryl ring wherein X04-21-2011
20110059475STABILISATION OF BLOOD CELL CONJUGATES - The invention relates to methods and kits for stabilising blood cell conjugates in blood samples for subsequent analysis. The invention particularly relates to methods and kits for use in fixing and stabilising platelet aggregates in blood samples, and methods for detecting the degree of platelet aggregation in a sample. The invention extends to kits for monitoring the efficacy of anti-thrombotic treatment regimes using platelet aggregation analysis. Two compositions with aliphatic aldehydes and a buffer are employed in a consecutive order. The second composition comprises addition a chelating agent.03-10-2011
20110027835METHODS OF MODIFYING NUCLEIC ACIDS IN HOST CELLS - A method of double crossover homologous recombination in a host cell comprising: a first homologous recombination event between a donor DNA molecule comprising a first element of a selectable allele and an acceptor DNA molecule comprising a second element of the selectable allele in the host cell, thereby to form a product of the first homologous recombination event in the host cell; and a second homologous recombination event within the product of the first homologous recombination event, thereby to form a product of the second homologous recombination event in the host cell which confers a selectable phenotype on the host cell, wherein the selectable phenotype arises following and in dependency on the formation of a selectable allele from the first and second elements of the selectable allele.02-03-2011
20100137523NANOPARTICLES AND FABRICATION THEREOF - Creation of nanoparticle structures in two and three dimensions is advantageous in providing a number of functions such as in relation to catalytic, optical, electronic and magnetic propertied and other actions. Fabrication of such structures poses a considerable technical challenge. A block copolymer pair is used as a matrix to spatially organizes and aligns loaded inorganic materials in the form of nanoparticles. The inorganic precursors are selectively incorporated to a specific block of a di or tri block copolymer so that through solvent evaporation, reduction and mechanical working such as LAOS the orientation and positioning of the block copolymers nanoparticles are obtained into a desired structure.06-03-2010
20100107621POWER CONVERSION - A wind energy converter 05-06-2010
20100105021STABILISATION OF BIOLOGICAL CELL MARKERS - The invention provides compositions which stabilise the expression of cell surface markers. The invention further provides methods and kits comprising such compositions for use in stabilising the expression of cell surface markers. The invention is especially concerned with compositions for use in stabilising the expression of cell surface markers (such as cell activation markers) present on blood cells, such as platelets. The invention extends to methods, apparatus and kits for detecting platelet activation, and to kits for monitoring the efficacy of anti-thrombotic treatment regimes.04-29-2010
20100028445POLYMER - The invention provides compositions comprising a polyamidoamine (PAA) polymer comprising a pendant disulphide, sulphydryl, or activated sulphydryl moiety, and methods for their manufacture. The invention extends to the use of such polyamidoamine polymers to form cross-linked compositions, and hydrogels comprising the same, and the use of such compositions in various biological and non-biological applications, such as the delivery of biomolecules to target sites, and for tracking fluid flows. The invention also provides carrier particles, which may be used to deliver biomolecules, and to methods of treatment. The invention also provides a fluid tracking system for monitoring fluid flow.02-04-2010
20090312237REGULATING FAT AND CARBOHYDRATE OXIDATION IN MUSCLE TISSUE COMPRISING CONTROLLING GARNITINE CONTENT IN MUSCLE - Methods, compositions and substances for regulating fat and carbohydrate oxidation in the muscle tissue of human and/or animal bodies, which involve controlling the carnitine content of the muscle tissue. Regulating carbohydrate and fat oxidation, and particularly increasing the level of fat oxidation in accordance with the present invention, by providing substances compositions and methodologies in accordance with the present invention, enable medicaments to be manufactured and methodologies employed that find use in the treatment of disorders and conditions of the human and/or animal body caused by impairment of the usual level of fat oxidation, including obesity and type 2 diabetes.12-17-2009
20090306487PHOTOPLETHYSMOGRAPHY - A photoplethysmograph device includes a light source for illuminating a target object. A modulator drives the light source such that the output intensity varies as a function of a modulation signal at a modulation frequency. A detector receives light from the target object and generates an electrical output as a function of the intensity of received light. A demodulator with a local oscillator receives the detector output and produces a demodulated output,insensitive to any phase difference between the modulation signal and the oscillator, indicative of blood volume as a function of time and/or blood composition. A number of demodulators may be provided to derive signals from multiple light sources of different wavelengths, or from an array of detectors. The plethysmograph may operate in a transmission mode or a reflectance mode. When in a reflectance mode, the device may use the green part of the optical spectrum and may use polarising filters.12-10-2009
20090198038Novel Catalysts for the Polymerisation of Carbonyl-Containing or Cyclic Monomers - The present invention relates to metal/organic complexes of Formula (I), (II), (III), (IV), (V) and (VI) that are useful as catalysts for the polymerisation of carbonyl-containing or cyclic monomers. Typical polymerisation reactions are, for example, those of lactides. R is independently selected at each occurrence from the group comprising: hydrogen, hydrocarbyl and substituted hydrocarbyl, M is a Lewis-acidic metal, and, if present, X is any suitable counter ion.08-06-2009
20080267930Biological Materials and Uses Thereof - A method of producing a reprogrammed cell or reprogrammed cell nucleus, comprising exposing a differentiated cell, or the nucleus of a differentiated cell to a cell or cell extract thereof derived from an oocyte, egg, ovary or early embryo of a cold blooded vertebrate, wherein the cold blooded vertebrate has one or more of the following properties: (i) a primitive vertebrate body plan including laterally projecting ribs and/or spinal projections; (ii) germ cells which do not contain germ plasm; and/or (iii) the oocyte, egg, ovary or early embryo cell or cell from which the cell extract is derived, expresses a highly conserved form of Oct-4 and/or nanog. There is also provided uses of the reprogrammed cells.10-30-2008
20080220081Water-Dispersible Xanthan Gum Containing Composition - One aspect of the present invention relates to a readily water-dispersible particulate composition comprising by weight of dry matter at least 10% of xanthan gum and not more than 60% of starch, said composition being characterised in that the xanthan gum present in the composition can be dispersed completely within 2 minutes in distilled water of 25° C. at a concentration of 0.7% based on the dry weight of xanthan. The particulate xanthan gum compositions of the present invention exhibit unique viscosity enhancing properties that are dependent on the electrolyte levels of the aqueous environment in which they are applied. The favourable properties of the xanthan compositions according to the invention can be realised without resorting to chemical modification of the xanthan gum. The xanthan compositions according to the present invention can be applied advantageously in e.g. food products and oil drilling fluids.09-11-2008

Patent applications by THE UNIVERSITY OF NOTTINGHAM