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THE UNIVERSITY OF MELBOURNE

Victoria, AU

THE UNIVERSITY OF MELBOURNE Patent applications
Patent application numberTitlePublished
20120064109IMMUNOGENIC COMPOSITION AND USES THEREOF - The present invention provides an immunogenic composition comprising an antigen and a dendritic cell targeting component. A charged group is covalently attached to a dendritic cell ligand and is electrostatically associated with the dendritic cell targeting component.03-15-2012
20120059188HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS - The present invention relates to halogenated compounds of formula (I) with the substituents as described within the specification. The compounds may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation.03-08-2012
20120024382NOVEL COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE IN HETEROJUNCTION DEVICES - The invention relates to novel polyaromatic and polyheteroaromatic compounds and derivatives thereof. The compounds display high solubility in organic solvents. A further aspect of the invention relates to the use of the novel compounds in the fabrication of organic film based heterojunction devices. In one form the devices display high conversion efficiencies in solar cell applications.02-02-2012
20120019242METHOD AND APPARATUS FOR MONITORING A PROPERTY OF A SAMPLE - The present disclosure provides a method of monitoring a property of a sample, such as a nanoscopic property of the sample. The method comprises the steps of providing a quantum probe having a quantum state and exposing the quantum probe to the sample in a manner such that the property of the sample, in the proximity of the quantum probe, affects quantum coherence of the quantum probe. The method also comprises detecting a rate of quantum decoherence of the quantum probe to monitor the property of the sample. Further the present disclosure provides an apparatus for monitoring a property of a sample.01-26-2012
20120003234Osteoarthritis treatment - The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA). In accordance with the present invention, an antagonist of GM-CSF can be effective in the treatment of osteoarthritis. An antagonist of GM-CSF includes, but is not limited to, an antibody that is specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.01-05-2012
20110305632PROCESS FOR THE PREPARATION OF ASYMMETRICAL BIS(THIOSEMICARBAZONES) - The present invention relates to a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method and methods of treatment and imaging utilising some of the new bis(thiosemicarbazones).12-15-2011
20110293517Nitrogen-Containing Macrocyclic Conjugates As Radiopharmaceuticals - The present invention relates to compounds that are useful as metal ligands and which either contain a molecular recognition moiety or can be bound to a molecular recognition moiety and methods of making these compounds. Once the compounds that contain a molecular recognition moiety are coordinated with a suitable metallic radionuclide, the coordinated compounds are useful as radiopharmaceuticals in the areas of radiotherapy and diagnostic imaging. The invention therefore also relates to methods of diagnosis and therapy utilising the radiolabelled compounds of the invention.12-01-2011
20110287027Pain treatment - The present invention relates generally to a method for the treatment and prophylaxis of pain. In accordance with the present invention, it is proposed that antagonists of GM-CSF are effective in the treatment of pain. Antagonists of GM-CSF include, but are not limited to, antibodies which are specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.11-24-2011
20110263450ALZHEIMER'S DISEASE BIOMARKERS - The invention provides a biomarker for qualifying Alzheimer's disease status, the biomarker being detectable in a biological sample containing blood cellular elements and being derived from amyloid precursor protein or amyloid β peptide. Particularly the biomarker includes an Aβ 1-42 or Aβ 1-43 species (monomer) and, or an Aβ 1-42 dimer. An alternative or additional biomarker includes an APP cathepsin D cleavage product or includes a biomarker identifiable by a peak of molecular weight of about 9962 or 9980 Daltons when identified by SELDI-TOF MS utilising antibody WO2.10-27-2011
20110262473SYNTHETIC VACCINE COMPONENT - The present invention relates generally to the field of synthetic vaccines, components thereof and methods for producing same. More particularly, the present invention provides a component of synthetic vaccines and its use in a modular approach to vaccine production.10-27-2011
20110256528ANALYTE DETECTION ASSAY - A rapid and sensitive analyte detection assay is based on whispering gallery modes of fluorescently labelled microspheroidal particles. Ligands for the analyte, such as nucleic acids, are anchored to the particles. The fluorescent labels may comprise fluorophores or quantum dots. In the latter case, the particles may comprise melamine formaldehyde. The assay may be used to detect analytes in aqueous samples.10-20-2011
20110250353Process for the preparation of a cross-linked multilayer film - The present invention provides a process for the preparation of a multilayer film, in particular, a cross-linked multilayer macromolecular film.10-13-2011
20110217366IMMUNOPOTENTIATING COMPOSITION - The present invention provides an immunopotentiating composition which comprises an antigen or antigen-inducing substance, and a carrier comprising a biocompatible material for effectively increasing an immune response derived from an antigen. The present invention further provides a method of producing an antibody by administering said immunopotentiating composition to a mammal or bird, thereby modulating the immune response in said mammal or bird and recovering the antibody produced.09-08-2011
20110213129Diagnostics and treatments of periodontal disease - This invention relates to the PrtR-PrtK cell surface protein of 09-01-2011
20110186756METHOD OF FABRICATING A SINGLE PHOTON SOURCE - The present disclosure provides a method of fabricating a single photon source. The method comprises the steps of providing a substrate with a visual feature and providing a plurality of particles positioned on the substrate. The particles are positioned in the proximity of the visual feature and include a particle that is arranged for single photon emission in response to a suitable excitation. The method also includes characterising photon emission from the particles to identify the single photon emission and thereby identifying an approximate location of the particle arranged for single photon emission relative to the visual feature. Further, the method includes imaging the visual feature and an area in the proximity of the visual feature and thereby imaging the particle arranged for single photon emission. In addition, the method includes moving the particle arranged for single photon emission to a predetermined position comprising coupling a suitable device to the particle and lifting the particle using the suitable device.08-04-2011
20110174995SINGLE PHOTON EMISSION SYSTEM - The present disclosure provides a method of forming a single photon emission system and a single photon emission system. The method comprises providing a single photon source arranged for single photon emission at a predetermined wavelength in response to a suitable excitation. The single photon source comprises a particle for generating the single photons. The method also comprises providing an optical pump source arranged to provide the suitable excitation in the form of suitable photons. In addition, the method comprises adjusting a pathway of the photons provided by the optical pump source and a position of the single photon source relative to each other so that the single photon source is located at a predetermined location relative to the pathway of the photons provided by the optical pump source and in use single photons are emitted by the single photon source. Providing the single photon source comprises identifying the particle for generating the single photons at a location that is remote from the predetermined location.07-21-2011
20110107467POLYSACCHARIDE SYNTHASES (H) - The present invention relates generally to polysaccharide synthases. More particularly, the present invention relates to (1,3;1,4)-β-05-05-2011
20110021815HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS - The present invention relates to halogenated compounds of formula (I) with the substituents as described within the specification. The compounds may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation.01-27-2011
20110017676FLOTATION AIDS AND PROCESSES FOR USING THE SAME - This invention relates to particulate and/or liquid droplet separation processes from liquids containing the same and the use of specific chemical additives to control surface wetting, hydrophobicity and surface forces in such processes.01-27-2011
20100290651PULSE STIMULATION GENERATION METHOD - A method of generating stimulation pulses for application by an auditory prosthesis. The method comprises: processing an audio input to obtain time shifted frequency data in which frequency data of one or more frequencies is temporally shifted relative to one or more other frequencies, the time shifted frequency data of each frequency representing the variation in energy at the frequency over time, and generating stimulation pulses to be applied by the auditory prosthesis from the time shifted frequency data.11-18-2010
20100266623SYNTHETIC, SELF ADJUVANTING VACCINES - The present invention relates generally to the field of immunotherapy, and more particularly to immunomedicaments in the form of lipopeptides which induce an antibody response to drugs of dependence, and uses thereof in the treatment and prevention of drug addiction.10-21-2010
20100215593IONIC COMPLEXES - The present invention provides a phosphopeptide or phosphoprotein (PP) stabilised amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP08-26-2010
20100209341TREATMENT OF CHRONIC INFLAMMATORY CONDITIONS - A method for the treatment of a chronic inflammatory condition in a patient which comprises administration to the patient of an agent which blocks or inhibits IL-3 signalling events in the patient.08-19-2010
20100178057SIGNAL METHOD AND APPARATUS - Methods and apparatus for generating and processing a signal are disclosed. The signal may comprise a plurality of mutually orthogonal subcarriers constituting a plurality of bands. The signal may be either an optical or a radio frequency signal.07-15-2010
20100130497Therapeutic Compounds - Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity; or derivatives thereof, analogues thereof, pharmaceutically acceptable salts thereof, and metabolites thereof; with the proviso that the compound is not Tranilast.05-27-2010
20100034908Porphyromonas gingivalis polypeptides and nucleotides - The present invention relates to isolated 02-11-2010
20100021163METHOD AND SYSTEM FOR POLARIZATION SUPPORTED OPTICAL TRANSMISSION - A method comprising splitting a received optical signal into split optical signals, the split optical signals being at least initially orthogonally polarized, coherently detecting at least one of the split optical signals and generating an electrical signal indicative thereof, and processing said electrical signal, the processing being adapted for received optical signals with orthogonal frequency division multiplexing (OFDM) modulation. A transmission system, a transmitter and a receiver are also provided.01-28-2010
20090274702Method of treatment and Agents useful for same - The present invention relates generally to a method for the treatment and prophylaxis of inflammatory conditions. The present invention is predicated in part on the identification of cells of the monocyte/macrophage lineage being critical for inflammation and, in particular, chronic inflammation. In accordance with the present invention, it is proposed that the reduction in levels of monocyte/macrophage-type cells and/or a reduction in the production of inflammatory and pro-inflammatory mediators by these cells, especially locally, is effective in reducing inflammatory conditions. The present invention further provides animal models useful for screening for reducing levels of monocyte/macrophage-type cells and/or reducing the production of inflammatory and pro-inflammatory mediators of these cells.11-05-2009
20090169568Antigenic Complex for the Diagnosis and Treatment of Porphyromonas Gingivalis Infection - The present invention provides a purified multimeric complex form 07-02-2009
20090050824METHOD OF FABRICATING A STRUCTURE FROM DIAMOND MATERIAL OR DIAMOND-LIKE CARBON MATERIAL - A method of fabricating a structure from diamond material or diamond-like carbon material, and a structure according to the method, the method comprising the steps of imposing a structural transformation on the crystallographic structure of the material in a first region located at a first depth below a surface of the material; imposing a structural transformation on the crystallographic structure of the material in a second region located at a second depth below the surface of the material and above of the first region, the second depth being selected so that the first region is separated from the second region by a third region; and removing at least a portion of the material of the first and second regions; wherein the structural transformations are imposed so that the crystallographic structure of the third region is largely unaffected and the third region has opposite surface portions from which material of the first and second regions has been removed.02-26-2009
20090022672FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION - The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions.01-22-2009
20080255044Method of treatment - The present invention relates generally to a method of treatment and in particular a method of treating disorders of the nervous system such as arising from or during disease or injury. The method of the present invention involves manipulating expression of Eph receptors or their functional equivalents to increase or decrease expression or function depending on the condition being treated.10-16-2008
20080254023Treating Gliosis, Glial Scarring, Inflammation or Inhibition of Axonal Growth in the Nervous System by Modulating Eph Receptor - The present invention relates to a method of treating disorders of the nervous system and more particularly disorders associated with a gliotic response and/or an inflammatory response within the central nervous system and to therapeutic agents useful for same. More particularly, the present invention involves a method of preventing or reducing the amount of Eph receptor-mediated gliosis and/or glial scarring and/or inflammation and/or Eph receptor-mediated inhibition of axonal growth which occurs during and/or after disease or injury to the nervous system. The present invention also facilitates the identification of therapeutic agents which modulate Eph receptor-mediated signaling. The method and therapeutic agents of the present invention are useful for treating a range of nervous system diseases, conditions and injuries including, inter alia, paralysis induced by physiological-, pathological- or trauma-induced injury to the brain or spinal cord.10-16-2008

Patent applications by THE UNIVERSITY OF MELBOURNE