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The University of Massachusetts

Boston, MA US

The University of Massachusetts Patent applications
Patent application numberTitlePublished
20110271403Metal Resistant Plants, and Methods of Manufacture Thereof - Disclosed herein is a transgenic plant transformed with an isolated nucleic acid comprising a plant arsenite-inducible RNA-associated protein coding sequence operatively linked to a plant-expressible transcription regulatory sequence, wherein the plant arsenite-inducible RNA-associated protein (AIRAP) coding sequence encodes a polypeptide that is at least 95% identical to a polypeptide sequence of SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, or SEQ ID NO:14, wherein the plant arsenite-inducible RNA-associated protein coding sequence encodes a polypeptide that confers resistance to an environmental stress, wherein greater than or equal to about 25% of transgenic plants are resistant to an environmental stress, and wherein the environmental stress inhibits the growth of wild type plants.11-03-2011
20110177554SECRETED FRIZZLED RELATED PROTEIN, SFRP, FRAGMENTS AND METHODS OF USE THEREOF - The invention stems from the discovery that sFRP and fragments thereof can bind to members of the Wnt family of proteins and cause an increase in Wnt biological activity. Furthermore, fragments of sFRP that do not contain the CRD domain are shown to bind to Wnt proteins and modulate Wnt biological activity. Accordingly, the invention provides these sFRP fragments and variants of these fragments, as well as vectors and host cells containing nucleic acid sequences encoding the sFRP fragments and variants.07-21-2011
20110118415CRYSTAL NUCLEATING AGENTS, CRYSTALLINE POLYMER COMPOSITION, METHODS OF MANUFACTURE THEREOF, AND ARTICLES THEREOF - A polymer composition, including: a first copolymer, including a first monomer unit derived from a monomer of Formula A:05-19-2011
20100076940METHOD FOR PROVIDING MAXIMAL CONCURRENCY IN A TREE STRUCTURE - Techniques for providing maximal concurrency while ensuring no deadlock in a tree structure are provided. The techniques include accessing a minimum number of one or more nodes to perform an operation.03-25-2010
20080268239REINFORCED POLYMERIC MATERIALS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a low molecular weight compound that exists in the form of a second crystalline phase; wherein the second crystalline phase is dispersed within the first organic polymer phase. Disclosed herein too is a polymeric composite comprising a first organic polymer that forms a first organic polymer phase; and a second phase that comprises a crystalline organic polymer, wherein the crystalline organic polymer has a different molecular structure from the first organic polymer; wherein the second phase is not covalently bonded to the first organic polymer phase and wherein the second phase has an average particle size of about 1 to about 20 micrometers.10-30-2008
20080230514METHOD OF PRODUCING NANOPATTERNED TEMPLATES - Nanopatterned substrates can be prepared by a method that includes forming a block copolymer film on a substrate, annealing the block copolymer film, surface reconstructing the annealed block copolymer film, coating an etch-resistant layer on the surface reconstructed block copolymer film, etching the resist-coated block copolymer film to create an etched article comprising a nanopatterned substrate, and separating the etch-resistant layer and the block copolymer film from the nanopatterned substrate. The method is applicable to a wide variety of substrate materials, avoids any requirement for complicated procedures to produce long-range order in the block copolymer film, and avoids any requirement for metal functionalization of the block copolymer.09-25-2008
20080229444METAL RESISTANT PLANTS, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF - Disclosed herein is a transgenic plant transformed with an isolated polynucleotide comprising a plant arsenate reductase coding sequence operatively linked to a plant-expressible transcription regulatory sequence. Also disclosed are methods to limit metal or metal ion accumulation in a harvested plant tissue comprising growing the transgenic plant; and harvesting plant tissue having reduced metal or metal ion accumulation. Further disclosed herein is method of making a transgenic plant transformed with an isolated polynucleotide comprising a plant arsenate reductase coding sequence operatively linked to a plant-expressible transcription regulatory sequence.09-18-2008
20080207504SECRETED FRIZZLED RELATED PROTEIN, sFRP, FRAGMENTS AND METHODS OF USE THEREOF - The invention stems from the discovery that sFRP and fragments thereof can bind to members of the Wnt family of proteins and cause an increase in Wnt biological activity. Furthermore, fragments of sFRP that do not contain the CRD domain are shown to bind to Wnt proteins and modulate Wnt biological activity. Accordingly, the invention provides these sFRP fragments and variants of these fragments, as well as vectors and host cells containing nucleic acid sequences encoding the sFRP fragments and variants.08-28-2008

Patent applications by The University of Massachusetts