| THE UNIVERSITY OF BIRMINGHAM Patent applications |
| Patent application number | Title | Published |
|---|
| 20110038881 | PROGNOSTIC ASSAY FOR DETERMINING T CELL RESPONSE TO HLA ANTIGENS AND USE THEREOF IN FIELD OF TISSUE TRANSPLANTATION - The invention provides an in vitro method of determining whether an individual is at risk of, or undergoing, graft damage or rejection of immune origin and/or damage of immune origin to non-graft tissue using polypeptides derived from a major histocompatibility complex (MHC) class I human leukocyte antigen (HLA), such as HLA-A2, and derivatives or analogues thereof. | 02-17-2011 |
| 20100279324 | Assay For Detecting Mycobacterial Infection - Methods for assessing a mycobacterial infection in a subject comprise exposing at least one CD1 molecule or analogue to mycolic acid or a mycolic acid analogue, subsequently incubating the at least one CD1 molecule or analogue with a sample comprising at least one T cell isolated from the subject, and measuring the T cell response and/or the number of mycolic acid specific T cells present in the T cell sample. | 11-04-2010 |
| 20100104876 | PIEZOELECTRIC COMPOSITE MATERIAL - The present invention provides a method for producing a composite material comprising an array of piezoelectric fibres, the method comprising: (a) providing: (a1) a plurality of first strips comprising a piezoelectric material or a precursor to a piezoelectric material, and a first carrier, and (a2) a plurality of second strips comprising a decomposable material, and a second carrier; (b) placing said pluralities of said first and second strips alternately on top of one another to form a stack in which at least a portion of said first strips is separated from adjacent first strips by a second strip; (c) a heating step comprising heating said stack to remove said first and second carriers and said decomposable material; (d) impregnating said stack with a filler material to form a composite stack of piezoelectric strips; and (e) cutting said stack to form a composite material comprising an array of piezoelectric fibres. In an alternative method the cutting (e) is performed before the heating step (c). The methods allow for the production of fibre arrays with mean fibre spacing of 5 ym or less. | 04-29-2010 |
| 20090297475 | CYSTEINE DIOXYGENASE POLYMORPHISMS - The invention relates to the detection and identification of polymorphisms in cysteine dioxygenase (CDO) for the use of that diagnosis to identify a propensity in a patient towards rheumatoid arthritis and/or to have side effects with a number of drugs, to nucleic acid and isolated proteins encoding the polymorphisms, to assays for CDO activity and for the identification of compounds affecting CDO activity, and additionally to use of interferon-γ optionally in combination with different compounds, to treat rheumatoid arthritis. | 12-03-2009 |
| 20090105343 | Cancer Therapy And Medicaments Therefor - The present invention relates to a novel cancer therapy, particularly, but not exclusively, to a prostate, bladder and breast cancer therapy and to Compositions and medicaments for use in said therapy. In one aspect there is provided a method of treating a patient afflicted with cancer comprising administering to the patient a therapeutically effective amount of a nuclear receptor ligand and an HDAC (histone deacetylases) inhibitor wherein said nuclear receptor ligand is not a ligand for the vitamin D receptor. | 04-23-2009 |
