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The United States of America, as represented by th e Secretary, Dept. of Health and Human Services

The United States of America, as represented by th e Secretary, Dept. of Health and Human Services Patent applications
Patent application numberTitlePublished
20110150768COMPOSITIONS AND METHODS FOR DELIVERING INHIBITORY OLIGONUCLEOTIDES - The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.06-23-2011