THE TRUSTEES OF THE UNIVERSITY OF COLUMBIA IN THE CITY OF NEW YORK
THE TRUSTEES OF THE UNIVERSITY OF COLUMBIA IN THE CITY OF NEW YORK Patent applications | ||
Patent application number | Title | Published |
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20150010579 | Treatment and Prevention of Gardnerella Vaginalis Infections - The present invention is drawn to the nucleic and amino acid sequences encoding vaginolysin (VLY) toxin from | 01-08-2015 |
20130281493 | Method for Treating Cancer Harboring a p53 Mutation - A method for determining if a subject with cancer or precancerous lesions or a benign tumor, will respond to treatment with an inhibitor selected from the group comprising an inhibitor of one or more enzymes in the mevalonate pathway, an inhibitor of geranylgeranyl transferase, an inhibitor of farnesyl transferase or an inhibitor of squalene synthase, by (i) obtaining a sample of the cancer cells, precancerous cells or benign tumor cells from the subject, (ii) assaying the cells in the sample for the presence of a mutated p53 gene or a mutant form of p53 protein or a biologically active fragment thereof, and (iii) if the cells have the mutated p53 gene or mutant form of the p53 protein, then determining that the subject will respond to treatment with the inhibitor or combinations thereof. Some embodiments are directed to treatment with the inhibitors. | 10-24-2013 |
20130217585 | Quantitative Total Definition of Biologically Active Sequence Elements - A method and apparatus include preparing a library of molecules that can be sequenced. The library includes multiple instances of each possible member of a k-mer. The library is sequenced to determine the relative frequency of each member of the k-mer in the library. The library is contacted with a biochemical system. A population of output molecules is sequenced to determine the relative frequency of each member of the k-mer in the population of output molecules. Each output molecule is related to a product of a process of the biochemical system and carries a k-mer related to a corresponding k-mer of a library molecule involved in the process. Effectiveness of each member of the k-mer is determined based on the relative frequency of each member of the k-mer in the population of output molecules and the relative frequency of the corresponding k-mer in the library. | 08-22-2013 |