The Trustees of Dartmouth College Patent applications |
Patent application number | Title | Published |
20160084788 | Molecularly Imprinted Polymer Sensors and Methods For Manufacturing The Same - A molecularly imprinted polymer sensor for sensing a target molecule includes (a) a polymer film that is molecularly imprinted with the target molecule and includes a conductive polymer having resistance sensitive to binding with the target molecule and a structural polymer providing porosity to the polymer film, and (b) interdigitated electrodes, located on a surface of the polymer film, for measuring a change in the resistance to sense said binding. | 03-24-2016 |
20150374308 | Method And Apparatus For Medical Imaging Using Differencing Of Multiple Fluorophores - A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images. | 12-31-2015 |
20150306246 | MAGNETIC NANOPARTICLES, COMPOSITES, SUSPENSIONS AND COLLOIDS WITH HIGH SPECIFIC ABSORPTION RATE (SAR) - Iron oxide nanoparticles and nanocomposites with organic molecules embedded in their structure, having exceptionally high SAR values, are provided for biological, medical (for example, drug delivery, hyperthermia, etc.) and other uses. | 10-29-2015 |
20150148661 | System And Apparatus For Porously-Encapsulated Magnetic-Nanoparticle Biosensors - A system for measuring analyte concentrations has porous-walled nanocontainers containing multiple magnetic nanoparticles, the magnetic nanoparticles coated with a selective binder that is analyte-responsive and binds a the analyte, an indicator substance releasable from the selective binder by the analyte, or an indicator substance cleavable by the analyte, apparatus for exposing the nanocontainers to a fluid potentially containing the analyte, and magnetic spectroscopy of Brownian motion sensing apparatus for detecting agglutination of the nanoparticles or binding of analyte to the nanoparticles. The system is used in a method comprising coating magnetic nanoparticles with a selective binder, encapsulating the magnetic nanoparticles in porous nanocontainers, exposing the nanocontainers to a fluid potentially containing analyte, using magnetic spectroscopy of Brownian motion sensing apparatus to detect agglutination or binding of the nanoparticles, and translating Brownian motion spectra to analyte concentrations. | 05-28-2015 |
20150038872 | MULTIPLE-ELECTRODE ELECTRICAL IMPEDANCE SENSING BIOPSY SAMPLING DEVICE AND METHOD - A biopsy sampling device has an inner trocar having a sampling opening, an outer needle with 4 or more electrodes on it, an impedance measuring apparatus coupled to drive current through a first and a second electrode, while measuring voltages through a third and fourth electrodes to measure an impedance of tissue adjacent to the electrodes, the inner trocar slideably engaged within the central cavity of the outer needle such that its sharpened tip and sampling opening can protrude from an end of the outer needle and be removed to capture a sample in the sampling opening. The device is used to obtain biopsy samples by advancing the device into an organ while observing impedance of tissue near or adjacent the device before the operator withdraws the trocar to obtain a biopsy sample of an inclusion in the organ. | 02-05-2015 |
20140378843 | Method And Apparatus For Quantitative Hyperspectral Fluorescence And Reflectance Imaging For Surgical Guidance - An imaging system includes an illumination device for illuminating a target. A surgical microscope receives light from the target, the surgical microscope comprising at least one optical output port at which at least a portion of the received light is provided as an output from the surgical microscope. A tunable filter receives the portion of the received light provided as the output from the surgical microscope, the tunable filter being tunable to pass a filtered portion of the received light, the filtered portion of the received light having a plurality of wavelengths selected by the tunable filter and provided as output from the tunable filter. A high-resolution, broad-bandwidth electronic camera receives the light of a plurality of wavelengths selected by the tunable filter, the electronic camera converting the light of a plurality of wavelengths selected by the tunable filter to a plurality of electrical signals. A processor processes the plurality of electrical signals to form an image of the target. | 12-25-2014 |
20140375337 | Planar Probe And System For Measuring Dielectric Properties Of Biological Materials - A probe sensor has a printed circuit comprising a coplanar transmission line, a ground plane, a plated-through contact via, and a part-circular ring of ground vias surrounding the contact via. The coplanar transmission line and ground plane are formed on a first layer of the printed circuit, and the contact via and part-circular ring of ground vias are plated with a conductive biocompatible material on a second layer of the printed circuit. A system uses a network analyzer with the probe to measure electrical properties of biological tissue. Also described is a method of using the system to determine qualities of stored blood. | 12-25-2014 |
20140362186 | METHOD AND APPARATUS FOR CALIBRATION OF STEREO-OPTICAL THREE-DIMENSIONAL SURFACE-MAPPING SYSTEM - A system for, and method of, extracting a surface profile from a stereo pair of images obtained at an arbitrary setting S of an optical system, includes determining surface profile reconstruction parameters for images obtained with the optical system at a reference setting So of the optical system; determining warping parameters for a digital image processor for warping images obtained with the optical system at the arbitrary setting S into images corresponding to the reference setting So; obtaining the stereo pair of images from at least one camera of the optical system; warping the stereo pair of images into images corresponding to the reference setting So, and using the surface profile reconstruction parameters to determine the surface profile. In a particular embodiment, the surface profile is passed to a computer model of tissue deformation and used to determine an intra-surgery location of a tumor or other anatomic feature of tissue. | 12-11-2014 |
20140286821 | FE-NI-MN-AL-CR ALLOYS AND METHODS FOR PRODUCTION THEREOF - Alloys including iron, nickel, manganese, aluminum and chromium are disclosed. The alloys have high strength and ductility. The alloys are prepared from readily available transition metals, and can be used in applications where properties similar to steel are necessary or advantageous. | 09-25-2014 |
20140276230 | POROELASTIC DYNAMIC MECHANICAL ANALYZER FOR DETERMINING MECHANICAL PROPERTIES OF BIOLOGICAL MATERIALS. - A system for determining parameters of porous media or material, which in an embodiment is biological tissue, includes an actuator and a displacement monitor. The actuator is adapted to apply a displacement to tissue at a particular frequency selected from a range of frequencies, and the force monitor adapted to monitor a mechanical response of tissue. The system also has a processor coupled to drive the actuator and to read the mechanical response, the processor coupled to execute from memory a poroelastic model of mechanical properties of the material, and a convergence procedure for determining parameters for the poroelastic model such that the model predicts mechanical response of the tissue to within limits. | 09-18-2014 |
20140269198 | Beamforming Sensor Nodes And Associated Systems - A beamforming sensor node has an array of pressure wave sensors and beamforming circuitry. Each pressure wave sensor is configured within a unique processing channel including a time delay circuit for producing a signal, with a phase offset, representative of received pressure waves at said pressure wave sensor. The beamforming circuitry includes the time delay circuits for all processing channels and (a) sets the phase offset of each processing channel and (b) parallel processes all signals from the array of pressure wave sensors through respective time delay circuits to form a first coherent beam-formed signal from the node. A secondary beamforming node combines coherent beam-formed signals from the plurality of sensor nodes to produce a combined acoustic signal representative of received pressure waves at all sensor nodes. | 09-18-2014 |
20140242237 | Molecularly Imprinted Polymer For Wine Extraction - Disclosed herein are compositions of, and methods of use for, molecularly imprinted polymers useful for extracting and/or detecting target molecule compounds of wine. | 08-28-2014 |
20140220706 | Molecularly Imprinted Polymer for Detecting Waterborne Target Molecules and Improving Water Quality - This disclosure relates to the field of molecularly imprinted polymers for detecting or removing target molecules. | 08-07-2014 |
20140219926 | Biodegradable Iron Oxide Nanoparticle Gel for Tumor Bed Therapy - A biodegradable iron oxide nanoparticle gel for hyperthermia treatment of cancer includes a polysaccharide-based carrier matrix and starch-coated iron oxide nanoparticles. The gel has sufficient deformability to integrate into a diffuse tumor site, adheres to tissue and has sufficient mechanical properties to remain in place during hyperthermia treatment. The gel releases iron oxide nanoparticles for uptake by cancerous cells at the tumor margin. | 08-07-2014 |
20140158020 | Ice-Tempered Hybrid Materials - A metal-polymer composite scaffold includes metal particles coupled with polymer binder, the scaffold having regions of aligned porosity with a gradient. In a particular embodiment, the metal particles include stainless steel. The metal particles have sizes equal to or smaller than 3 μm. The scaffold has Young's modulus is below 950 MPa. The polymer binder includes chitosan and gelatin. The composite also includes ethanol. The composite has porosity of at least 70%. Systems and methods for producing such metal polymer composite scaffold are also provided. | 06-12-2014 |
20140141122 | CONVERSION OF SOYBEAN HULLS TO ETHANOL AND HIGH-PROTEIN FOOD ADDITIVES - Soybean hull fermentation methods that produce food additives having a high protein content are disclosed. The protein is generally present as unhydrolyzed and non-racemized protein that possesses a complete amino acid profile. The food additive is suitable for consumption by a wide variety of animals, including humans. | 05-22-2014 |
20140114150 | Method And System For Using Cherenkov Radiation To Monitor Beam Profiles And Radiation Therapy - A system for providing monitored radiation therapy has a high energy radiation source, apparatus for excluding uncontrolled ambient light, and apparatus for collecting light emitted from a subject. The system has apparatus for spectrally analyzing the collected light, and a processor for determining oxygenation or other metabolic function of tissue within the subject from spectral analysis of the collected light. The system monitors radiation therapy by providing a beam of high energy radiation; collecting Cherenkov and/or photoluminescent light from the subject, the light generated along the beam; spectrally analyzing the light; and determining oxygenation or metabolic function of tissue from the spectral analysis. Beam profile of the system is calibrated by imaging from multiple angles Cherenkov and/or photoluminescent light emitted by a phantom placed in the beam in lieu of a subject, captured images are analyzed to determine beam profile. | 04-24-2014 |
20140105912 | VISTA MODULATORS FOR DIAGNOSIS AND TREATMENT OF CANCER - The present disclosure relates to compositions and therapeutic methods for activating an immune response in a patient in need thereof. In a preferred embodiment, the subject methods and compositions are able to antagonize the activity of VISTA, a naturally occurring “checkpoint” protein which contributes to immune tolerance, optionally in combination with an antagonist of a second checkpoint pathway such as PD-1. For example, such methods and compositions may be suitable for preventing and treating colon cancer or another cancer. An exemplary VISTA antagonist, specifically, an anti-VISTA antibody, is demonstrated herein to activate an immune response against cancer cells in vitro and in vivo, thereby conferring protective anti-tumor immunity which decreased tumor burden. Additionally, an additive benefit was observed when a VISTA antagonist was used in combination with a second checkpoint protein antagonist, specifically, an antibody against PD-1 ligand (PD-L1). | 04-17-2014 |
20140020689 | Method And Apparatus Utilizing Magnetic Nanoparticles For Sterilizing Female Placental Mammals, Including Women - A method for local heating includes placing first magnetic material in a first lumen, and a second magnetic material in a second lumen from the first magnetic material to a magnetically permeable rod, then applying alternating magnetic fields. The first lumen may be a fallopian tube. A method of occluding fallopian tubes uses a catheter to inject first magnetic material into the tubes, injecting second magnetic fluid into uterus, introducing a magnetically-permeable rod into vagina, positioning a second end of the rod over the fallopian tube and applying an alternating magnetic field to the first magnetic material to heat it. The method is performed with apparatus having a coil wound over a magnetically-permeable rod, a high frequency AC generator coupled to the coil, a first magnetic fluid capable of generating heat in an alternating magnetic field, and a second magnetically-permeable magnetic fluid capable of conducting magnetic fields through a lumen. | 01-23-2014 |
20130345268 | Methods and Compositions for the Treatment of RAS Associated Disorders - The instant disclosure relates to compositions that may be useful as therapeutic agents for the treatment of disorders associated or caused by Ras deregulation or dysregulation, for example, disorders associated with alterations in the NF1 gene such as neurofibromatosis type I, fungal infections such as those caused by | 12-26-2013 |
20130338479 | Apparatus And Method For Surgical Instrument With Integral Automated Tissue Classifier - A method and apparatus is described for optically scanning a field of view, the field of view including at least part of an organ as exposed during surgery, and for identifying and classifying areas of tumor within the field of view. The apparatus obtains a spectrum at each pixel of the field of view, and classifies pixels with a kNN-type or neural network classifier previously trained on samples of tumor and organ classified by a pathologist. Embodiments use statistical parameters extracted from each pixel and neighboring pixels. Results are displayed as a color-encoded map of tissue types to the surgeon. In variations, the apparatus provides light at one or more fluorescence stimulus wavelengths and measures the fluorescence light spectrum emitted from tissue corresponding to each stimulus wavelength. The measured emitted fluorescence light spectra are further used by the classifier to identify tissue types in the field of view. | 12-19-2013 |
20130322215 | Acoustic Sensor With An Acoustic Object Detector For Reducing Power Consumption In Front-End Circuit - An acoustic object detector for detecting presence of an acoustic signal is provided. The acoustic object detector includes a number of bandpass filters. Each bandpass filter is configured to convert an input signal into an analog signal within a frequency band. The acoustic object detector also includes a number of spike generating circuits each coupled to the respective bandpass filter. Each spike generating circuit is configured to generate a series of spike signals based upon an adaptive threshold for the analog signal. The acoustic object detection further includes a decision circuit configured to generate a digital signal at a time-frequency point from the series of spike signals. | 12-05-2013 |
20130302870 | Flowthrough Pretreatment Of Lignocellulosic Biomass And Selective Separation Of Components Using High-Temperature Nanoporous Membranes - A new and improved biomass conversion system is disclosed using high-temperature flow-though pretreatment and a nanoporous membrane to provide more digestible biomass for subsequent conversion to biofuels. | 11-14-2013 |
20130206374 | GEOMETRY OF HEAT EXCHANGER WITH HIGH EFFICIENCY - The present disclosure includes geometry of a two-fluid heat exchanger to provide higher energy efficiency than conventional heat exchangers. The geometry is based upon sequential branching of nearly circular passages in sets, followed by some deformation and twisting of the sequential branches that intermingle flow passages of one fluid with flow passages of another fluid. The flow passages gradually vary in dimension from larger branching at fluid entrance and exit to smaller branching in the middle section of the heat exchanger. The heat exchanger is substantially symmetric, with the sequential branching in the first half being mirrored as serial regrouping in the second half. The present disclosure also provides stacking methods and layered manufacturing methods for fabricating the three-dimensional geometry of the heat exchanger. | 08-15-2013 |
20130186455 | METHOD OF FORMING SINGLE-CRYSTAL SEMICONDUCTOR LAYERS AND PHOTOVALTAIC CELL THEREON - A method for forming single crystal or large-crystal-grain thin-film layers deposits a thin-film amorphous, nanocrystalline, microcrystalline, or polycrystalline layer, and laser-heats a seed spot having size on the order of a critical nucleation size of the thin-film layer. The single-crystal seed spot is extended into a single-crystal seed line by laser-heating one or more crystallization zones adjacent to the seed spot and drawing the zone across the thin-film layer. The single-crystal seed line is extended across the thin-film material layer into a single-crystal layer by laser-heating an adjacent linear crystallization zone and drawing the crystallization zone across the thin-film layer. Photovoltaic cells may be formed in or on the single-crystal layer. Tandem photovoltaic devices may be formed using one or several iterations of the method. The method may also be used to form single-crystal semiconductor thin-film transistors, such as for display devices, or to form single-crystal superconductor layers. | 07-25-2013 |
20130176010 | High-Efficiency Base-Driver Circuit For Power Bipolar Junction Transistors - A system or module has a 3-or-more layer current-controlled switching device, such as a bipolar power transistor, for driving a load and a base driver circuit coupled to drive it. The driver has a buck-converter configuration for efficiently driving the switching device. In an embodiment, the driver has an inductor, the inductor having a first terminal coupled to a base of the bipolar junction transistor, a high-side switching device coupled to drive a second terminal of the inductor; and a rectification device coupled to the second terminal of the inductor. The driver also has a control circuit for providing a sequence of pulses through the high-side switching device when a control signal indicates the bipolar junction transistor is to be turned on. | 07-11-2013 |
20130170670 | System And Method For Automatically Remixing Digital Music - Systems and methods augment a target media with a plurality of source media. The target media and source media are processed to form time frequency distributions (TFDs). Target features are extracted from the associated TFD and source features are extracted from each of the associated source TFDs. The target features are segmented into temporal portions that are compared with each of the plurality of source features to determine one or more matched source features having nearest matches to the target feature segments. Portions of the source media associated with the matched source features are mixed with the target media to form an augmented target media, wherein the mixing is based upon a probabilistic mixing algorithm that uses a distance between the matched target feature and source features to define an amplitude of each portion of the source media. | 07-04-2013 |
20130136734 | ANTI-CD154 ANTIBODIES HAVING IMPAIRED FcR BINDING AND/OR COMPLEMENT BINDING PROPERTIES AND RELATED THERAPIES - Improved anti-CD154 antibodies are provided herein which have ablated FcR binding and/or complement binding/activation. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein. | 05-30-2013 |
20130135450 | 3d Scanning Laser Systems And Methods For Determining Surface Geometry Of An Immersed Object In A Transparent Cylindrical Glass Tank - Systems and methods generate a 3D model of a surface of an object immersed in a transparent liquid within a stationary cylindrical transparent tank. First and second laser line projectors and a camera are rotated around a central axis of the cylindrical tank. The first and second laser line projectors each generate a laser line perpendicular to a plane or rotation and aligned with the center of rotation. The camera images the object. An image from the camera is captured at each of several angular positions of the camera relative to a reference position of the stationary cylindrical tank. The captured images are processed to determine, for each laser line within each image, a plurality of 3D positions where the laser line is incident upon a surface of the object. In embodiments, images are corrected with ray tracing or image warping and registration functions. | 05-30-2013 |
20130129234 | Perceptual Rating Of Digital Image Retouching - A method is provided for automatically providing a digital image rating of photo retouching. The method includes the step of receiving at a computer, including a processor, a first set of pixel data of an original image and a second set of pixel data of a retouched image. The method also includes using the processor to determine a plurality of geometric statistics and a plurality of photometric statistics from the first and second sets of pixel data. The method further includes the step of using the processor to quantify a rating of the retouched image based upon the geometric statistics and photometric statistics to indicate deviation of the retouched image from the original image. A system is also provided to perform the steps. | 05-23-2013 |
20130123613 | Magnetic Particle Heating System And Method For Occlusion Of The Fallopian Tube - In a magnetic particle heating method for occlusion of the Fallopian tubes, biocompatible magnetic particles are delivered transcervically to the entrance of the Fallopian tube. Placement of the particles (e.g., magnetic nanoparticles) in the Fallopian tube is confirmed, and a coil is positioned about or proximate the patient's abdomen. Alternating current is applied to the coil to couple magnetic energy into the nanoparticles, heating the nanoparticles and causing thermal injury to the Fallopian tube. Temperature within the Fallopian tube may be monitored during heating, to prevent overheating, or alternating current may be applied for a predetermined treatment time, with or without temperature monitoring. Each Fallopian tube may be treated with nanoparticles and the two tubes heated simultaneously, or the tubes may be sequentially treated and heated. Treatment may be visualized via in-office hysteroscope, fluoroscopy or ultrasound. Thermal injury to the Fallopian tube mucosa occludes the tube and completes sterilization. | 05-16-2013 |
20120315493 | JOINING OF PARTS VIA MAGNETIC HEATING OF METAL ALUMINUM POWDERS - A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration. | 12-13-2012 |
20120295306 | Modified CIPA Gene From Clostridium Thermocellum for Enhanced Genetic Stability - Bacteria consume a variety of biomass-derived substrates and produce ethanol. The scaffoldin gene cipA from | 11-22-2012 |
20120281947 | System And Method For Coupling A Multi-Mode Optical Fiber To A Single Mode Optical Fiber - A multi-mode to single mode optical interface device includes an optically pumped edge emitting semiconductor laser device and a lens. The optically pumped edge emitting semiconductor laser device includes (1) a gain area, and (2) an edge located single mode output. The lens focuses a multi-mode optical fiber output beam into a substantially line shaped output beam focused onto the gain area of the optically pumped edge emitting semiconductor laser device. A method for converting a multi-mode optical signal into a single mode optical signal includes (1) focusing the multi-mode optical signal onto a gain area of an optically pumped edge emitting semiconductor laser using at least a line focusing lens, and (2) converting the multi-mode optical signal into the single mode optical signal using the semiconductor laser. | 11-08-2012 |
20120234816 | Systems And Methods For Windshield Deicing - Cost efficient, lightweight and rapid windshield deicing systems and methods are disclosed. The systems utilize step-up converters or inverters, or dual-voltage batteries, to provide a voltage high enough to deice a windshield in less than thirty seconds at ambient temperatures above −10 C. Some of the disclosed systems include sensors for deicing element and ambient temperatures, and in some embodiments windspeed. All embodiments have a controller for limiting deicing time to that sufficient to melt a boundary layer of ice. The controller of embodiments with sensors computes deicing time as a function of ambient temperature. Embodiments interact with wiper systems to enable wipers to clear ice once the boundary layer is melted. | 09-20-2012 |
20110278417 | System And Methods For Smoothly Inverting One Or More Faces Of A Cubical Device - A system and method for inverting a cubical device | 11-17-2011 |
20110256601 | MODIFICATION OF HYDROGENASE ACTIVITIES IN THERMOPHILIC BACTERIA TO ENHANCE ETHANOL PRODUCTION - Bacteria consume a variety of biomass-derived substrates and produce ethanol. Hydrogenase genes have been inactivated m | 10-20-2011 |
20110149281 | ROTARYFROG SYSTEMS AND METHODS - Systems and methods determining amplitude and phase versus frequency of an incoming beam of pulsed laser light. An apparatus is set to an initial configuration to split the incoming beam into two beams of substantially equal intensity, delay one of the two split beams for a delay period t and recombine the two split beams to form a recombined beam. The recombined beam shines onto a thick SHG crystal at rotation angle θ and light emitted from the thick SHG crystal is detected as data and stored with reference to the delay period t and the angle θ. The thick SHG crystal is rotated by an angle δθ and the steps of splitting, delaying, recombining, shining, detecting, storing, and rotating are repeated until the thick SHG crystal has completed 360° of rotation. The delay period is increased by δt and the steps of splitting, delaying, recombining, shining, detecting, storing, rotating, repeating and increasing are repeated until a selected beam delay period range has been completed. The stored data is processed to determine amplitude and phase versus frequency of the incoming beam of pulsed laser light. | 06-23-2011 |
20110079631 | Joining Of Parts Via Magnetic Heating Of Metal-Aluminum Powders - A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase nanocrystalline magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration. | 04-07-2011 |
20110041967 | Eutectic Alloys of the Type FE 25-35 NI 15-25 MN 30-40 AL 10-20 M 0-5 and Methods for Production Thereof - Alloys, formed by a eutectic transformation of the type Fe25-35 Ni15-25 Mn30-40 Al10-20 MO-5, are disclosed. M is selected from chromium, molybdenum, carbon and combinations thereof. The alloys have high strength and ductility. The alloys are prepared from readily available transition metals, and can be used in applications where properties similar to steel are necessary or advantageous. | 02-24-2011 |
20110034806 | Systems And Methods For Combined Ultrasound And Electrical Impedance Imaging - A dual imaging probe | 02-10-2011 |
20100299615 | System And Method For Injecting Sensed Presence Into Social Networking Applications - A method for injecting sensed presence into social networking applications includes receiving sensor data associated with a user ( | 11-25-2010 |
20100075363 | Recombinant Yeast Strains Expressing Tethered Cellulase Enzymes - Recombinant yeast strains that saccharify, ferment and grow on insoluble and crystalline forms of cellulose are disclosed herein. The yeast strains express tethered cellulases including cellobiohydrolase, endoglucanase and β-glucosidase. The recombinant organisms are particularly suited for consolidated bioprocessing. | 03-25-2010 |
20100039124 | Molecularly Imprinted Polymer Sensor Systems And Related Methods - A molecularly imprinted polymer (MIP) sensor including a substrate, two or more electrodes, a conductive layer applied to the substrate and a molecularly imprinted polymer layer applied to the conductive layer is disclosed herein The MIP sensor may form part of an MIP sensor system that can be used to detect and quantify target molecules. | 02-18-2010 |
20100021177 | System And Method For Imaging Objects Through Turbid Media - A method for imaging objects through turbid media includes generating a repetitive pulsed light beam under control of a pulse shaper, propagating the light beam through turbid media, and receiving and imaging the light beam at a sensor. Propagation through turbid media causes scattering of the light, and the sensor captures scattered pulses to produce an image. The pulse shaper controls pulse width, frequency, repetition rate and chirp of the generated light pulses according to a feedback signal received from the sensor, to improve image quality. A system for imaging objects through turbid media includes a laser for generating a light beam; a pulse shaper for controlling said light beam, and a sensor, in communication with the pulse shaper, for capturing the image of said light beam through a turbid medium. Pulse width is less than 250 femtoseconds to reduce attenuation of the light beam through the turbid medium. | 01-28-2010 |
20100015282 | Conversion Of Soybean Hulls To Ethanol And High-Protein Food Additives - Soybean hull fermentation methods that produce food additives having a high protein content are disclosed. The protein is generally present as unhydrolyzed and non-racemized protein that possesses a complete amino acid profile. The food additive is suitable for consumption by a wide variety of animals, including humans. | 01-21-2010 |
20090250449 | System And Method For Deicing Of Power Line Cables - A system and method for deicing power transmission cables divides the cable into sections. Switches are provided at each end of a section for coupling the conductors together in parallel in a normal mode, and at least some of the conductors in series in an anti-icing mode. When the switches couple the conductors in series, an electrical resistance of the cable section is effectively increased allowing self-heating of the cable by power-line current to deice the cable; the switches couple the conductors in parallel for less loss during normal operation. In an alternative embodiment, the system provides current through a steel strength core of each cable to provide deicing, while during normal operation current flows through low resistance conductor layers. Backup hardware is provided to return the system to low resistance operation should a cable overtemperature state occur. | 10-08-2009 |
20090247847 | SYSTEMS AND METHODS FOR TOMOGRAPHIC IMAGE RECONSTRUCTION - Optical tomography systems that provide light of multiple distinct wavelengths from a plurality of sources are described. The systems direct light into mammalian tissue, and light from the mammalian tissue is collected at a plurality of reception points. Collected light from each reception point is separated according to its wavelength, and received by a photodetector to produce path attenuation signals representing attenuation along paths between the source locations and the reception points. An image construction system generates a tomographic image of the mammalian tissue from the path attenuation signals. One embodiment of an optical imaging system includes an optical coherence tomography-near infrared probe. The systems and methods may utilize a spectral derivative approach that provides insensitivity to the boundary and boundary artifacts in the signal, thereby improving the quality of the reconstructed images. | 10-01-2009 |
20090239277 | Thermophillic Organisms For Conversion Of Lignocellulosic Biomass To Ethanol - Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of | 09-24-2009 |
20090235682 | Pulse Electrothermal Mold Release Icemaker With Safety Baffles For Refrigerator - An icemaker and a refrigerator having an icemaker are discussed. The icemaker has pulse-electrothermal ice release and includes an ice-making tray having several ice forming portions in which water is stored and ice is formed; and a housing surrounding the ice-making tray provided with at least one cold air inlet and/or ice ejection port through which cold air is supplied and ice released along a bent channel. The cold air inlet and/or ice ejection ports are baffled to prevent contact with a user's fingers and thereby reduce the possibility of electric shock. | 09-24-2009 |
20090235681 | Pulse Electrothermal Mold Release Icemaker For Refrigerator Having Interlock Closure And Baffle For Safety - The present document relates to an icemaker having a pulse electrothermal ice release system for separating ice bodies from an ice mold. The pulse electrothermal ice release system operates by applying an electric current through the ice mold through two wires. Safety apparatus for preventing electric shock to users of the icemaker is described. A refrigerator having the icemaker, and an operating method of the icemaker are disclosed. In an embodiment, the safety apparatus interrupts current flow through both wires. | 09-24-2009 |
20090188658 | Compact Helical Heat Exchanger With Stretch To Maintain Airflow - A heat exchanger for exchanging heat between gasses such as air and a liquid or gaseous coolant has narrow spacing between exchanger surfaces for high efficiency. To avoid undue obstruction of gas flow due to ice buildup on the exchanger surfaces, the heat exchanger is equipped with sensors to monitor the gas flow and an actuator that widens the spacing between exchanger surfaces such that gas flow remains unimpeded. Embodiments provide for defrosting of the exchanger surfaces when an limit on spacing of exchanger surfaces is reached, and for relaxing the spacing to the original narrow spacing when defrosting is completed. | 07-30-2009 |
20090050800 | ELECTRONIC TIME-OF-FLIGHT MASS SELECTOR - A method of selecting ions includes generating a group of ions, accelerating the group of ions through a flight region towards an electronic mass selector grid, and selectively varying a voltage applied to the electronic mass selector grid, such that only a selected subset of the group of ions passes through the grid. An apparatus for selecting ions includes an ion generator, an ion accelerator for accelerating ions into a flight region, and an electronic mass selector grid responsive to an applied voltage to pass a subset of the ions from the flight region. An apparatus for detecting a threat molecule includes an ion generator for generating ions from a mixed gas stream, an ion accelerator for accelerating the ions into a flight region, and an electronic mass selector grid. The grid passes only a subset of the ions, such as ions and/or ionized fragments of the threat molecule. | 02-26-2009 |
20090017503 | Method and Apparatus for Saccharide Precipitation From Pretreated Lignocellulosic Materials - A method for separating saccharide components and lignin fractions from a concentrated acid treated lignocellulosic biomass is disclosed. The method involves precipitating the saccharide components by adding an organic solvent to the biomass slurry. The acid may then be recovered, for example, by filtration or by countercurrent washing and the organic solvent may be flashed and recycled. During acid recovery and organic recovery steps, two main lignocellulose components (hemicellulose and lignin) as well as minor components such as acetic acid are separated as well. The method decreases the amount of cellulase required for hydrolysis, increases hydrolysis rates, reduces formation of inhibitor molecules, increase sugar yields, produces high value by-products such as high quality lignin and hemicellulose, and decreases energy and equipment costs. | 01-15-2009 |
20080223842 | Systems And Methods For Windshield Deicing - Cost efficient, lightweight and rapid windshield deicing systems and methods are disclosed. The systems utilize step-up converters or inverters, or dual-voltage batteries, to provide a voltage high enough to deice a windshield in less than thirty seconds. | 09-18-2008 |
20080196429 | Pulse Electrothermal And Heat-Storage Ice Detachment Apparatus And Method - Systems and methods for pulse electrothermal and heat-storage ice detachment. A pulse electrothermal ice detachment apparatus includes one or more coolant tubes, and optionally, fins in thermal contact with the coolant tubes. The tubes and/or fins form a resistive heater. Apparatus applies electrical power to the resistive heater, generating heat to detach ice from the tubes and/or the fins. A freezer unit forms a heat-storage icemaking system having a compressor and a condenser for dissipating waste heat, and coolant that circulates through the compressor, the condenser and a coolant tube. The coolant tube is in thermal contact with an evaporator plate. A tank, after the compressor and before the condenser, transfers heat from the coolant to a heating liquid. The heating liquid periodically flows through a heating tube in thermal contact with the evaporator plate, detaching ice from the evaporator plate. | 08-21-2008 |