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THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY IF

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY IF Patent applications
Patent application numberTitlePublished
20100190697UNDERCARBOXYLATED/UNCARBOXYLATED OSTEOCALCIN INCREASES BETA-CELL PROLIFERATION, INSULIN SECRETION, INSULIN SENSITIVITY, GLUCOSE TOLERANCE AND DECREASES FAT MASS - The present invention relates to methods and compositions for treating and diagnosing disorders related to energy metabolism and the OST-PTP signaling pathway involving gamma-carboxylase, osteocalcin and adiponectin. Such disorders include, but are not limited to, metabolic syndrome, glucose intolerance, diabetes types 1 and 2, atherosclerosis and obesity.07-29-2010