THE REGENTS OF THE UNIVERSITY OF CALIFORNIA A CALIFORNIA CORPORATION Patent applications |
Patent application number | Title | Published |
20140275532 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS - The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer. | 09-18-2014 |
20140274959 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS - The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer. | 09-18-2014 |
20140221966 | Kalman Filter Based On-Off Switch for Insulin Pump - Techniques for controlling an insulin pump include determining values for parameters selected from a group including a first prediction time horizon, a predicted glucose threshold (Goff) for turning the insulin pump off, a maximum shut off time within a time window, and duration of the time window. A safety rule is determined based on the maximum shut off time within the duration. Glucose readings are collected up to a current time. An expected current glucose value G and glucose temporal rate of change are determined based only on the glucose readings and a Kalman filter configured for noisy glucose readings. A glucose level (Gh1) is predicted for a future time that is the prediction time horizon after the current time. A command is issued to shut off the insulin pump if it is determined both that Gh1 is less than Goff and that the safety rule is satisfied. | 08-07-2014 |
20140170140 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMYELITIS OPTICA - The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis. | 06-19-2014 |
20130164751 | CARCINOMA DIAGNOSIS AND TREATMENT, BASED ON ODC1 GENOTYPE - The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other invasive cancers where cellular proliferation and carcinogenesis is linked, in part, to high levels of ODC activity and increased cellular polyamine contents, and b) for selecting the corresponding treatment options for such patients based on the allelic nucleotide sequence or SNP at position +316 of the ODC1 promoter gene as well as cancer treatment methods, in each case, which include the determination of the ODC1 promoter +316 position genotype, as a means to guide treatment selection. | 06-27-2013 |
20130152933 | AUTOMATED FLUID DELIVERY SYSTEM AND METHOD - An automated fluid delivery system and method are disclosed. The system includes distensible tubing, a flow controller, and a fluid flow adjustment module. The fluid flow adjustment module may be configured to detect differential pressure in the tubing and adjust the flow controller to provide an amount of fluid through the tubing during inhalation. | 06-20-2013 |
20130076789 | AUGMENTED REALITY USING PROJECTOR-CAMERA ENABLED DEVICES - An augmented reality scene may be registered onto an arbitrary surface. A camera may capture an image of the arbitrary surface. The camera may analyze the surface geometry of the arbitrary surface. In some embodiments, a processing computing device may analyze data captured by the camera and an adjacent camera to reconstruct the surface geometry of the arbitrary surface. A scene may be registered to a three dimensional coordinate system corresponding to the arbitrary surface. A projector may project the scene onto the arbitrary surface according to the registration so that the scene may not display as being distorted. | 03-28-2013 |
20130070094 | AUTOMATIC REGISTRATION OF MULTI-PROJECTOR DOME IMAGES - Automatic registration of projectors and their images on a curved surface may be performed using non-linear optimization techniques. A camera may capture images on the curved surface. The camera may be un-calibrated. The camera parameters may be estimated using a non-linear optimization of data in the images of the curved surface. The images may be from multiple projectors. In some embodiments, registration may be view independent. | 03-21-2013 |
20120320200 | VIDEO FRAME SYNCHRONIZATION FOR A FEDERATION OF PROJECTORS USING CAMERA FEEDBACK - A method of audio and video synchronization may include capturing an image by each of a plurality of cameras. The images and audio may be compared with each other for synchronization. | 12-20-2012 |
20120308062 | DIRECT DRIVE MICRO HEARING DEVICE - A device and methods are provided for a hearing device. In one embodiment, a hearing device includes a microphone to receive sound, an interactive tip and actuator. The actuator can include an actuator element and preload force element to place the interactive tip in contact with a portion of an ear. The hearing device includes circuitry coupled to the microphone and actuator, the circuitry configured to process sound received by the microphone and drive the actuator based on processed sound, wherein the actuator drives the interactive tip relative to a portion of the ear based on one or more signals received from the circuitry. | 12-06-2012 |
20120283215 | PHARMACEUTICAL COMPOSITIONS WHICH INHIBIT FKBP52-MEDIATED REGULATION OF ANDROGEN RECEPTOR FUNCTION AND METHODS OF USING SAME - Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain, otherwise known as FKBP52 Targeting Agents (FTAs) are provided. These compositions of the present invention are found to specifically recognize the FKBP52 regulatory surface on the androgen receptor and inhibit FKBP52 from functionally interacting with the androgen receptor. Compositions comprising the pharmaceutical composition, as well as methods of use, treatment and screening are also provided. | 11-08-2012 |
20120251532 | ANTI-ALPHA V BETA 6 ANTIBODIES - Monoclonal antibodies that specifically bind to M.96. Also included are methods of using these antibodies to treat mammals having or at risk of having 006-mediated diseases, or to diagnose % Qmediated diseases. | 10-04-2012 |
20120027754 | Treatment and Prevention of Chronic Asthma Using Antagonists of Integrin AlphavBeta6 - The present invention relates to methods of asthma treatment and prevention using α | 02-02-2012 |
20110287007 | Treatment and Prevention of Chronic Asthma Using Antagonists of Integrin AlphavBeta6 - The present invention relates to methods of asthma treatment and prevention using α | 11-24-2011 |
20110281750 | Identifying High Risk Clinically Isolated Syndrome Patients - Disclosed herein are methods and kits for identifying clinically isolated syndrome (CIS) patients at high risk of developing multiple sclerosis (MS). | 11-17-2011 |
20110256605 | CELLS WITH NON-NATURAL PHYSIOLOGIES DERIVED BY EXPRESSING LIGHT-POWERED PROTON PUMPS IN ONE OR MORE MEMBRANES - Methods and procedures for designing and constructing microbes with the ability to harvest light energy are described. In certain embodiments, these methods and procedures are used to construct a photosynthetic yeast based on proteorhodopsin (PR) expression. Proteorhodopsin is a light powered proton pump used by some ocean bacteria to scavenge light energy. By illuminating single yeast cells expressing PR, controlled amounts of energy can be delivered to these cells. A light-harvesting yeast is a unique bioenergetics research platform for investigating the interplay of biofuel production, cellular ATP levels, and the proton-motive-force (pmf). Also, a strain of yeast with light-boosted biomass to biofuel conversion efficiency possesses direct industrial and commercial utility. | 10-20-2011 |
20110224223 | MTOR Modulators and Uses Thereof - The present invention provides methods and compositions for selective modulation of certain protein kinases, and especially mTor complexes. The methods and compositions are particularly useful in inhibiting mTor selectively for therapeutic applications. | 09-15-2011 |
20100048414 | NOVEL METHODS FOR PREDICTING AND TREATING TUMORS RESISTANT TO DRUG, IMMUNOTHERAPY, AND RADIATION - The present invention relates to methods for prognosis, diagnosis, and treatment of malignant tumors that were treatment resistant. The present invention provides methods of prognosis and diagnosis of multidrug resistant tumors through detection of the expression levels of nuclear co-repressor 2 (“N-CoR2”), histone deacetylases 3 (“HDAC3”), and their associated gene expression biomarkers. The present invention also provides methods of sensitizing tumors to anti-tumor therapeutics by disrupting HDAC3 activation, abrogating the N-CoR2-HDAC3 interaction, inhibiting the activity of either protein, or by down-regulating the expression of either protein. | 02-25-2010 |
20090231739 | MATRIX FORMULATION OF KOHLER INTEGRATING SYSTEM AND COUPLED NON-IMAGING LIGHT CONCENTRATOR - Methods for designing optical systems, including homogenizer element(s), that concentrate light from a distant source, such as the sun, onto a target device, such as a solar cell. | 09-17-2009 |
20090186036 | Anti-Alpha V Beta 6 Antibodies - Monoclonal antibodies that specifically bind to M.96. Also included are methods of using these antibodies to treat mammals having or at risk of having O06-mediated diseases, or to diagnose % Qmediated diseases. | 07-23-2009 |
20090028853 | TREATMENT AND PREVENTION OF CHRONIC ASTHMA USING ANTAGONISTS OF INTEGRIN ALPHAvBETA6 - The present invention relates to methods of asthma treatment and prevention using α | 01-29-2009 |
20080314568 | ANISOTROPIC THERMAL AND ELECTRICAL APPLICATIONS OF COMPOSITES OF CERAMICS AND CARBON NANOTUBES - Ceramic materials are converted to materials with anisotropic thermal properties, electrical properties, or both, by forming the ceramics into composites with carbon nanotubes dispersed therein and uniaxially compressing the composites in a direction in which a lower thermal or electrical conductivity is desired. | 12-25-2008 |