The Regents of the University of Calfornia Patent applications |
Patent application number | Title | Published |
20150099872 | REGULATION OF GALACTAN SYNTHASE EXPRESSION TO MODIFY GALACTAN CONTENT IN PLANTS - The disclosure provides methods of engineering plants to modulate galactan content. Specifically, the disclosure provides methods for engineering a plant to increase the galactan content in a plant tissue by inducing expression of beta-1,4-galactan synthase (GALS), modulated by a heterologous promoter. Further disclosed are the methods of modulating expression level of GALS under the regulation of a transcription factor, as well as overexpression of UDP-galactose epimerse in the same plant tissue. Tissue specific promoters and transcription factors can be used in the methods are also provided. | 04-09-2015 |
20140329705 | SALIVA COLLECTION, PROCESSING, STABILIZATION, AND STORAGE METHOD - Provided herein is an all-in-one saliva collection apparatus that collects saliva to allow for the filtration of saliva in order to separate saliva components, such as extracellular proteins and nucleic acids that are not present in intact cells, from the intact cells and debris remaining in the extracted sample. The filtered saliva samples can be aliquoted into two fractions for protein and/or nucleic acid analysis. The present invention further describes long term storage at ambient temperatures of filtered salivary nucleic acids, and long term storage at ambient temperatures of filtered salivary proteins added to an ethanol solution. The filtered cell-free saliva samples have diagnostic usefulness. | 11-06-2014 |
20120309648 | INTEGRATED MICROFLUIDICS FOR HIGHLY PARALLEL SCREENING OF CHEMICAL REACTIONS - A microfluidic system has a microfluidic mixer and a sample storage component that is in fluid connection with the microfluidic mixer. The microfluidic mixer has a mixing section; a target molecule input section that is in fluid connection with the mixing section, the target molecule input section being suitable to provide a fluid into the mixing section that contains molecules to be targeted by chemical reactions; a first reagent input section that is in fluid connection with the mixing section, the first reagent input section being structured to selectively provide a first reagent selected from a plurality of reagents to test a chemical reaction with the target molecules; a second reagent input section that is in fluid connection with the mixing section, the second reagent input section being structured to selectively provide a second reagent selected from a plurality of reagents to test a chemical reaction with the target molecules and said first reagent; and a neutral fluid input section that is in selectable fluid connection with the sample storage component, the neutral fluid input section being structured to selectively provide a neutral fluid into the sample storage component between successive samples provided to the sample storage component to separate successive samples in a stratified arrangement. | 12-06-2012 |
20090210371 | DATA ADAPTIVE PREDICTION FUNCTION BASED ON CANDIDATE PREDICTION FUNCTIONS - In one embodiment, a method for predicting an outcome is provided. The method comprises: determining a known data set of data, the known data set of data including an input variable and an output variable; determining a plurality of candidate prediction functions, each prediction function adapted to determine a candidate predicted outcome for the output variable using a different algorithm; determining a combination of the plurality of candidate prediction functions based on the known data set; determining a second set of data, the second set of data including data for the input variable; and determining, based on the input variable, a predicted outcome for the output variable using a data adaptive prediction function, wherein the data adaptive prediction function uses the combination of candidate predicted outcomes from the plurality of candidate prediction functions determined using the data from the input variable to determine the predicted outcome. | 08-20-2009 |