| The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabe Patent applications |
| Patent application number | Title | Published |
|---|
| 20110046182 | EFFICIENT ASPIRIN PRODRUGS - Aspirin is one of the most widely used drugs in the treatment of inflammation, pain and fever. It has more recently found application in the prevention of heart attacks and stroke and is being studied as a cancer chemopreventative agent. Despite its value aspirin continues to be underutilized because it causes gastric bleeding. The technology under development potentially removes this problem. It is designed to reduce contact between the drug and the intestinal lining. An isosorbide aspirinate prodrug compound is thus provided. The compound has the general structure as shown in general formula (I) wherein Y is a C | 02-24-2011 |
| 20100190841 | GENETIC SUPPRESSION AND REPLACEMENT - The invention relates to gene suppression and replacement. In particular, the invention relates to enhanced expression of suppression agents for suppressing gene expression in a cell and in vivo and replacement nucleic acids that are not inhibited by the suppression agent. Regulatory elements are included in expression vectors to optimize expression of the suppression agent and/or replacement nucleic acid. | 07-29-2010 |
| 20100160332 | a2-Adrenoceptor Ligands - The adrenergic receptors or adrenoceptors are a family of G-protein coupled receptors split into α and β subclasses. The adrenoceptors have important roles in regulating a myriad of physiological conditions and their malfunction has been implicated in the pathophysiology of a number of diseases. Disclosed herein are a series of novel compounds which are ligands of the alpha2-adrenoceptor (α | 06-24-2010 |
| 20100088624 | ANIMATION TOOL - An animation tool which is configured to enable a user to generate one or more animations for subsequent execution on a computer platform is described. The animation tool provides a plurality of graphical integers which a user can use to generate an animation. The graphical integers are divisible into graphical elements and graphical element effects, the effects being applied by a user onto an element and defining the viewing properties of that element. | 04-08-2010 |
| 20100046562 | TUNABLE LASER DEVICE AND A METHOD FOR PRODUCING LIGHT OF RESPECTIVE SELECTABLE WAVELENGTHS - A tunable laser device ( | 02-25-2010 |
| 20100016224 | COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE - The present invention relates to a method of enhancing a pro-inflammatory immune response through the administration of the DEAD-box protein DDX3, as encoded by SEQ ID NO:1. The invention further extends to a method of suppressing an aberrant immune response, such at that associated with autoimmune conditions, through inhibition of DDX3. The invention also extends to a method of suppressing a pro-inflammatory immune response through the administration of the vaccinia virus protein K7. The invention further extends to the provision of an attenuated poxvirus wherein the K7R gene which encodes for the K7 protein is deleted or rendered non-functional. Pharmaceutical compositions comprising DDX3 inhibitory compounds, such as K7, are also provided. | 01-21-2010 |
