| The McLEAN Hospital Corporation Patent applications |
| Patent application number | Title | Published |
|---|
| 20120022315 | Magnetic Field Treatment Techniques - The invention involves enhancing brain function by stimulating the brain using magnetic fields. Applications of the new methods include improving the condition of individuals with cognitive disorders, such as depression, and studying the effects of neural stimulation using induced electric fields. These techniques can avoid deleterious effects of psychotropic pharmaceutical treatments, and provide a relatively safe, comfortable, inexpensive means of direct cranial stimulation. | 01-26-2012 |
| 20120010219 | SALVINORIN DERIVATIVES AND USES THEREOF - The invention features salvinorin compositions that are selective for kappa opioid receptors; methods of treating mania by using a selective kappa receptor agonist; and methods of treating mood disorders, such as depressive disorders and manic disorders, using salvinorin compositions. | 01-12-2012 |
| 20110208439 | METHODS FOR MEASURING THE MAGNITUDE OF ATTENTION AND MOTOR ACTIVITY DISTURBANCE IN A SUBJECT - The invention features methods and systems to monitor changes in the magnitude of attentional disturbance and the magnitude of motor activity disturbance in a subject. The invention also features methods and systems for determining a subject's degree of concordance with individuals having an attentional disorder versus individuals not having an attentional disorder. The methods and systems of the invention can enable clinicians and consumers to ascertain both the severity of an attentional disorder as well as how much an individual changes over time, or with therapy. | 08-25-2011 |
| 20110208437 | METHOD AND APPARATUS FOR IDENTIFYING A SAFE AND EFFICACIOUS DOSING REGIMEN - The invention features methods and systems to provide, in one test session, information on the patient's sensitivity to a probe drug for treating attentional disorders. The methods and systems of the invention can enable clinicians and consumers to ascertain how much benefit an individual would derive from treatment, what dose would be required, and the acute effect of that dose on regularity and rhythmicity of their heartbeat. | 08-25-2011 |
| 20110104275 | METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS - The invention features methods and kits employing bromolysergide in therapies for the treatment of cluster headache disorders. | 05-05-2011 |
| 20110034446 | R(-)-2-METHOXY-11-HYDROXYAPORPHINE AND DERIVATIVES THEREOF - The invention features derivatives of R(−)-2-methoxy-11-hydroxyaporphines and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith. | 02-10-2011 |
| 20110008310 | METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY - The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities. | 01-13-2011 |
| 20100222296 | PYRIMIDINES, SUCH AS URIDINE, IN TREATMENTS FOR PATIENTS WITH BIPOLAR DISORDER - The invention is based on the discovery that specific dosages of pyrimidine compositions, such as uridine compositions, can be used to treat patients diagnosed with bipolar disorder. | 09-02-2010 |
| 20100081651 | R(-)-11-HYDROXYAPORPHINE DERIVATIVES AND USES THEREOF - The invention features derivatives of R(−)-11-hydroxyaporphines and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith. | 04-01-2010 |
| 20100056488 | CORTICOSTEROID CONJUGATES AND USES THEREOF - The invention features corticosteroids conjugated to either a charged group or a bulky group in a manner that resists in vivo cleavage, the resulting conjugate is a peripherally acting steroid with reduced activity in the central nervous system. The invention provides a method for treating a patient having an inflammatory disease by administering to the patient a corticosteroid conjugate. | 03-04-2010 |
| 20090221552 | Methods for the Treatment of ADHD and Related Disorders - The invention features methods, compositions, and kits for the treatment of attention deficit hyperactivity disorder and related behavioral disorders by administering an organic cation 3 (hOCT3) inhibitor. | 09-03-2009 |
| 20090202966 | Method For Assessing Auditory Attention And Vigilance - Provided are methods for assessing the attentional state of a subject by scoring the subject's response to auditory stimuli. The methods can be used to diagnose psychological and behavioral disorders, such as attention deficit disorder or hyperkinetic disorder. | 08-13-2009 |
| 20090048177 | Methods for the treatment of mood disorders - The invention features methods of treating mood disorders, such as manic disorders, and stabilizing moods by administering a kappa agonist or partial agonist to a subject in need thereof. | 02-19-2009 |
| 20080287917 | Apparatus and Method for Convection Enhanced Therapeutic Delivery - A system for convection enhanced delivery of therapeutic comprises one or more flexible, biocompatible microcatheters that are directed to a target location to deliver a therapeutic agent. The microcatheter is releasably coupled to a guide tube and directed to the desired location. The microcatheters are small and flexible in order to reach the target areas, minimize trauma at the injection site, and minimize reflux of the injectable therapeutic. | 11-20-2008 |
