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THE GOV'T OF THE USA as represented by THE SECTY, DEPT OF HEALTH AND HUMAN SERVICES

THE GOV'T OF THE USA as represented by THE SECTY, DEPT OF HEALTH AND HUMAN SERVICES Patent applications
Patent application numberTitlePublished
20090028900WEST NILE VIRUSES WITH MUTATIONS IN THE 3' TERMINAL STEM AND LOOP SECONDARY STRUCTURE FOR USE AS LIVE VIRUS VACCINES - The invention provides West Nile (WN) viruses and chimeric WN viruses having one or more mutations in the 3′ terminal stem loop secondary structure (3′SL) that results in decreased neurovirulence, methods of making such WN viruses, and methods for using these WN viruses to prevent or treat WN virus infection.01-29-2009