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The Govt. of the U. S. as Represented by the Secretary of the Dept. of Health and Human Svcs.

The Govt. of the U. S. as Represented by the Secretary of the Dept. of Health and Human Svcs. Patent applications
Patent application numberTitlePublished
20100280056IDENTIFICATION OF SUBJECTS LIKELY TO BENEFIT FROM STATIN THERAPY - Methods are provided herein to determine if a subject is a candidate for treatment with an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR). The method includes determining the presence of at least one polymorphism in the HMGCR gene in a sample from a subject. The presence of at least one polymorphism indicates that the subject is a candidate for treatment with a statin, for example to decrease risk of or treat cancer, cardiovascular disease, diabetes, obesity, inflammatory disease, or auto-immune disease.11-04-2010