| The Government of United States of America, as represented by the Secretary of the Navy Patent applications |
| Patent application number | Title | Published |
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| 20110097797 | Modular Functional Peptides for the Intracellular Delivery of Nanoparticles - Described are peptides for delivery of a nanoparticle to the cytosol, the peptide comprising: (a) a nanoparticle association domain; (b) a proline-rich spacer domain; (c) an uptake domain; and (d) a vesicle escape domain comprising a non-hydrolyzable lipid moiety, wherein the spacer domain is between the nanoparticle association domain and the uptake and vesicle escape domains, and wherein the peptide, when attached to an extracellular nanoparticle, is effective to induce uptake of the nanoparticle by a cell and delivery of the nanoparticle to the cytosol of the cell. Also described are methods of delivery of a nanoparticle to the cytosol of a cell, the method comprising providing to a cell a nanoparticle attached to such a peptide. Exemplary nanoparticles include quantum dots. | 04-28-2011 |
| 20100238957 | OPO Laser Mid-IR Wavelength Converter - A wavelength converter comprising an arsenic sulfide (As—S) chalcogenide glass fiber coupled to an optical parametric oscillator (OPO) crystal and a laser system using an OPO crystal coupled to an As—S fiber are provided. The OPO receives pump laser radiation from a pump laser and emits laser radiation at a wavelength that is longer than the pump laser radiation. The laser radiation that is emitted from the OPO is input into the As—S fiber, which in turn converts the input wavelength from the OPO to a desired wavelength, for example, a wavelength beyond about 4.4 μm. In an exemplary embodiment, the OPO comprises a periodically poled lithium niobate (PPLN) crystal. The As—S fiber can include any suitable type of optical fiber, such as a conventional core clad fiber, a photonic crystal fiber, or a microstructured fiber. | 09-23-2010 |
