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The Government of the U.S.A., as Represented by the Secretary, Department of health

The Government of the U.S.A., as Represented by the Secretary, Department of health Patent applications
Patent application numberTitlePublished
20090081212USE AND TARGETING OF CD98 LIGHT-CHAIN PROTEINS IN THERAPIES FOR THYROID HORMONE DISORDERS - The invention is related to the normalization of thyroid hormone transport by modulation of 4F2hc, CD981c, and the 4F2hc-CD981c heterodimer. Approaches to identify compounds that modulate thyroid hormone disorders, methods of identifying agonists and antagonists that modulate thyroid hormone disorders, and methods of making pharmaceuticals that ameliorate a thyroid hormone disorder are described herein.03-26-2009