| The Government of The United States of America, as Represented by the Secretary of Patent applications |
| Patent application number | Title | Published |
|---|
| 20110245210 | THALIDOMIDE ANALOGS - Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs. | 10-06-2011 |
| 20100319240 | SUCTION TRAP FOR COLLECTING RESTING MOSQUITOES - A method and apparatus are disclosed that can sample a wide variety of mosquitoes attempting to rest. Because all mosquitoes rest daily, biases of typical mosquito traps are avoided, such as targeted collections of host-seeking mosquitoes or gravid female mosquitoes. A particular advantage is the inclusion of blood-engorged mosquitoes in the resting collections. In one embodiment, the apparatus includes an open-sided pot designed to attract mosquitoes seeking a daytime resting location. The mosquitoes that enter a dark space of the pot are aspirated into a screened collection receptacle by means of a battery-powered fan. | 12-23-2010 |
| 20100239601 | METHOD OF IMMUNIZING HUMANS AGAINST SALMONELLA TYPHI USING A VI-REPA CONJUGATE VACCINE - This invention relates to conjugates of the Vi polysaccharide of | 09-23-2010 |
| 20100104507 | USE OF STERICALLY STABILIZED CATIONIC LIPOSOMES TO EFFICIENTLY DELIVER CPG OLIGONUCLEOTIDES IN VIVO - Sterically stabilized cationic liposomes (SSCL) encapsulating a K type oligodeoxynucleotide (ODN) including a CpG motif are disclosed. These SSCL encapuslating a K type ODN can be used to effectively deliver the ODN to a cell. A novel method is also disclosed for producing the SSCL encapsulating the K type ODN. Administration of the SSCL encapsulating a K type ODN and a chemotherapeutic agent, such as a chimeric molecule comprising a targeting molecule selected from the group consisting of an IL-13, and an anti-IL-13 receptor antibody; and an effector molecule selected from the group consisting of a | 04-29-2010 |
| 20100099138 | MULTIPLE-VALENT OPSONOPHAGOCYTIC ASSAY SELECTION PANEL ARRAYS AND USES THEREFOR - This application discloses a multivalent opsonophagocytosis assay that does not rely on counting of bacterial colonies to determine bacteria viability following opsonophagocytosis. Instead, the method uses a metabolic colorimetric indicator to determine if viable bacteria are present. Also disclosed are arrays that can be used to determine the viability of bacteria following opsonophagocytosis. | 04-22-2010 |
| 20090263825 | METHODS, IMMUNOASSAYS AND DEVICES FOR DETECTION OF ANTI-LIPOIDAL ANTIBODIES - Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, a method for immobilizing a lipoidal antigen, comprising cardiolipin, lecithin, and cholesterol, on a solid support (such as a nitrocellulose membrane) is described. The ability to immobilize a lipoidal antigen on a membrane satisfies a long-felt need for a membrane-based assay for the detection of anti-lipoidal antibodies. Also described are immunoassay devices for concurrently performing treponemal and non-treponemal tests for syphilis. | 10-22-2009 |
