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THE GENERAL HOSPITAL CORP.

THE GENERAL HOSPITAL CORP. Patent applications
Patent application numberTitlePublished
20110142973Compositions and methods for treating obesity, obesity related disorders and for inhibiting the infectivity of human immunodeficiency virus - The present invention relates to methods and pharmaceutical compositions for treating obesity or obesity-related disorders in a subject suffering from or predisposed to developing obesity or an obesity-related disorder, or for inhibiting the infectivity of HIV, by administering oleuropein, an analogue or derivative thereof, or the major metabolites of oleuropein including oleuropein aglycone, hydroxytyrosol, and elenolic acid or their analogues, or derivatives thereof, an iridoid glycoside, or a secoiridoid glycoside or analogues or derivatives thereof, or any combination of the foregoing including olive leave extract. The invention also relates to methods for screening/diagnosing a subject having, or predisposed to having obesity or a related disorder by measuring the expression profiles of an adipogenic gene selected from PPARγ2, LPL and αP2 gene and gene product, or other adipogenic, lipogenic, or lipolytic genes and gene products in an individual. The invention further provides for screening for novel oleuropein analogues.06-16-2011
20100321180ULTRASONIC COMPLIANCE ZONE SYSTEM - A system is provided for establishing a compliance zone and monitoring interactions therewith. The system includes a compliance zone designator and a wearable device. The compliance zone designator transmits an ultrasound signal to establish the compliance zone. The ultrasound signal may be encoded with information on the compliance zone. The compliance zone designator is configured for placement at a location in which the compliance zone is desired. The wearable device is separate from the compliance zone designator. The wearable device includes a compliance zone recognition component configured to recognize the compliance zone and identify one or more pre-defined interaction criteria for the compliance zone. When the wearable device is within the compliance zone, the compliance zone recognition component recognizes the compliance zone and identifies the interaction criteria of the compliance zone. Based on the interaction criteria the wearable device determines and records compliance with the interaction criteria. The recorded data is optionally used to set off real-time alerts. The recorded data is also optionally used in subsequent analysis and documentation of compliance with protocols.12-23-2010