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THE CURATORS OF THE UNIVERSITY MISSOURI

Columbia, MO US

THE CURATORS OF THE UNIVERSITY MISSOURI Patent applications
Patent application numberTitlePublished
20090099069MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.04-16-2009