| THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120135260 | FABRICATION OF NANO-TWINNED NANOPILLARS - Nanopillars with nanoscale diameters are provided where the nanopillar has uniformly aligned nano-twins either perpendicular or inclined by 1-90° to the pillar-axis with no grain-boundaries or any other features. | 05-31-2012 |
| 20120028420 | METHOD FOR REUSE OF WAFERS FOR GROWTH OF VERTICALLY-ALIGNED WIRE ARRAYS - Reusing a Si wafer for the formation of wire arrays by transferring the wire arrays to a polymer matrix, reusing a patterned oxide for several array growths, and finally polishing and reoxidizing the wafer surface and reapplying the patterned oxide. | 02-02-2012 |
| 20110244537 | REGIO- AND ENANTIOSELECTIVE ALKANE HYDROXYLATION WITH MODIFIED CYTOCHROME P450 - Cytochrome P450 BM-3 from | 10-06-2011 |
| 20110182994 | METHODS AND SYSTEMS FOR PRODUCTION OF NANOPARTICLES - Methods and systems for preparing nanoparticles. A source of a carrier fluid is connected to an inlet of a flow conduit, such as an intravenous solution administration tube with injection ports, such that the carrier fluid flows through the conduit. A substance (e.g., a drug solution or other substance solution) is introduced into the conduit at a first location causing substance nanoparticles to form within and continue to flow thought he conduit. A stabilizer is introduced into the conduit at a second location to cause a stabilizing effect on the nanoparticles. In some embodiments, the stabilizer may limit or deter agglomeration or growth of the nanoparticles, thereby limiting the size of the nanaparticles produced. | 07-28-2011 |
| 20100164073 | ELECTRICAL PASSIVATION OF SILICON-CONTAINING SURFACES USING ORGANIC LAYERS - Electrical structures and devices may be formed and include an organic passivating layer that is chemically bonded to a silicon-containing semiconductor material to improve the electrical properties of electrical devices. In different embodiments, the organic passivating layer may remain within finished devices to reduce dangling bonds, improve carrier lifetimes, decrease surface recombination velocities, increase electronic efficiencies, or the like. In other embodiments, the organic passivating layer may be used as a protective sacrificial layer and reduce contact resistance or reduce resistance of doped regions. The organic passivation layer may be formed without the need for high-temperature processing. | 07-01-2010 |
| 20100051478 | HIGH-THROUGHPUT SCREENING AND DEVICE FOR PHOTOCATALYSTS - The disclosure relates to compositions, devices and methods for screening of photocatalysts for water-splitting. | 03-04-2010 |
| 20090298148 | REGIO- AND ENANTIOSELECTIVE ALKANE HYDROXYLATION WITH MODIFIED CYTOCHROME P450 - Cytochrome P450 BM-3 from | 12-03-2009 |
| 20090264311 | Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use - The invention relates to novel variants of cytochrome P450 oxygenases. These variants have at least one mutation improving their ability to use peroxide as an oxygen donor as compared to the corresponding wild-type enzyme. The variants also have at least one mutation improving thermostability as compared to the parent enzyme or corresponding wild-type enzyme. Preferred variants include cytochrome P450 BM-3 heme domain variants having L52I, I58V, F87A, H100R, S106R, F107L, A135S, M145A/V, A184V, N239H, S274T, L324I, V340M, I366V, K434E, E442K, and/or V446I amino acid substitutions. | 10-22-2009 |
| 20090214762 | SPATIOTEMPORAL AND GEOMETRIC OPTIMIZATION OF SENSOR ARRAYS FOR DETECTING ANALYTES IN FLUIDS - Sensor arrays and sensor array systems for detecting analytes in fluids. Sensors configured to generate a response upon introduction of a fluid containing one or more analytes can be located on one or more surfaces relative to one or more fluid channels in an array. Fluid channels can take the form of pores or holes in a substrate material. Fluid channels can be formed between one or more substrate plates. Sensor can be fabricated with substantially optimized sensor volumes to generate a response having a substantially maximized signal to noise ratio upon introduction of a fluid containing one or more target analytes. Methods of fabricating and using such sensor arrays and systems are also disclosed. | 08-27-2009 |
| 20090142821 | Peroxide-driven cytochrome P450 oxygenase variants - The invention relates to novel variants of cytochrome P450 oxygenases. These variants have an improved ability to use peroxide as an oxygen donor as compared to the corresponding wild-type enzyme. These variants also have an improved thermostability as compared to the cytochrome P450 BM-3 F87A mutant. Preferred variants include cytochrome P450 BM-3 heme domain mutants having 158V, F87A, H100R, F107L, A135S, M145A/V, N239H, S274T, L3241, I366V, K434E, E442K, and/or V446I amino acid substitutions. | 06-04-2009 |
| 20090124515 | METHODS AND COMPOSITIONS FOR PREPARATION OF SELECTIVELY PROTECTED CARBOHYDRATES - The disclosure relates to engineered P450 polypeptides and use of such polypeptides in chemoenzymatic methods to construct selectively protected carbohydrates, which are useful as building blocks for preparation of carbohydrate derivatives and oligosaccharides | 05-14-2009 |
| 20080268517 | STABLE, FUNCTIONAL CHIMERIC CYTOCHROME P450 HOLOENZYMES - The present disclosure relates to cytochrome p450 fusion polypeptides, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides. | 10-30-2008 |
| 20080248545 | Methods for Generating Novel Stabilized Proteins - The disclosure provides methods for identifying and producing stabilized chimeric proteins. | 10-09-2008 |
