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The Brigham and Women's Hospital, Inc. Corporate Sponsored Research and Licensing

The Brigham and Women's Hospital, Inc. Corporate Sponsored Research and Licensing Patent applications
Patent application numberTitlePublished
20110237495FUNCTIONAL METABOLOMICS COUPLED MICROFLUIDIC CHEMOTAXIS DEVICE AND IDENTIFICATION OF NOVEL CELL MEDIATORS - The invention relates to the use of microfluidic chemotaxis device to identify novel active compounds of the metabolome and methods to characterize their actions on cell motility. The invention also includes the active compounds of the metabolome identified by the methods and devices disclosed herein. The results from these in vitro experiments were then correlated with in vivo physiologic responses to identify the downstream effects and therapeutic value. Thus, the invention provides novel methods for treating or preventing second organ injury resulting from ischemia-reperfusion in a patient in need thereof The invention also provides methods of treating, preventing or ameliorating connective tissue degeneration in a patient in need thereof. The invention also provides methods of treating or preventing bone loss. In addition, the invention provides method for inducing bone regeneration in patients in need thereof or preventing bone loss in patients suspected to be in need thereof.09-29-2011
20090317427Zwitterionic Polysaccharides for Promotion of Immune System Maturation and Health - Certain zwitterionic polysaccharides, including those naturally expressed by commensal 12-24-2009