20110275533 | Micro-RNAs as Markers for Tumor Progression - Disclosed are methods for diagnosing cancer or dysplasia in a sample of tissue, involving testing cells of the sample to assess whether miR-196a expression in cells of the sample is greater than a reference, wherein a greater expression of miR-196a in cells of the sample compared to the reference is indicative of cancer or dysplasia. The cancer or dysplasia may be esophageal cancer or esophageal dysplasia. Also disclosed are method for diagnosing cancer or dysplasia in a sample of tissue, comprising testing cells of the sample to assess whether the expression of ANXA1, KRT5, SPRR2C, or S100A9 in cells of the sample is reduced compared to a reference control, wherein said reduced expression in cells of the sample compared to the reference control is indicative of cancer or dysplasia. Also disclosed are kits and methods involving kits for the diagnosis of cancer or dysplasia. | 11-10-2011 |