| TEMASEK LIFE SCIENCES LABORATORY LIMITED Patent applications |
| Patent application number | Title | Published |
|---|
| 20120096595 | VIRUS INDUCED GENE SILENCING (VIGS) FOR FUNCTIONAL ANALYSIS OF GENES IN COTTON - The invention relates to the functional analysis of genes in cotton by employing the Virus Induced Gene Silencing (VIGS) method. More specifically this method induces gene silencing in cotton with the help of the Tobacco Rattle Virus (TRV) vectors RNA1 and RNA2 and phenotypic effects on the cotton plant can be analysed Moreover this invention also provides transient expression vector TRV RNA2 in order to transiently express genes in cotton plants and plant tissue under the influence of a strong subgenomic promoter. | 04-19-2012 |
| 20120073018 | JATROPHA CURCAS CURCIN GENES, TISSUE-SPECIFIC PROMOTERS AND GENERATION OF CURCIN-DEFICIENT TRANSGENIC JATROPHA PLANTS - The present invention relates to the isolation of | 03-22-2012 |
| 20120045473 | Biomolecule Surface Display and Uses Thereof - A vaccine for the treatment or prevention of a disease in a subject, wherein said disease is associated with an avian influenza virus, and wherein said vaccine comprises an expression vector comprising a nucleic acid encoding a hemagglutinin peptide, such that in use said hemagglutinin peptide is expressed by said expression vector in said subject. | 02-23-2012 |
| 20120003261 | DIGOXIN-LIKE FUNGAL GLYCOSIDE WITH CYTOTOXIC PROPERTIES: NOVEL ASSAY AND APPLICATIONS - The present invention provides methods of isolating cytotoxic metabolites from a fungus, and specific metabolites obtained from such methods. The present invention also provides methods of controlling fungal diseases in plants by treating the plants with cytotoxic metabolites as well as methods of treating cardiac arrhythmia in organisms in need of such treatment by administering the above-noted metabolites to such organisms. | 01-05-2012 |
| 20110265223 | FUNCTIONAL ANALYSIS OF JATROPHA CURCAS GENES - The present invention relates to the field of functional analysis of | 10-27-2011 |
| 20110256141 | Monoclonal Antibodies Specific to the Fusion Peptide From Hemagglutinin From Influenza A Viruses and Uses Thereof - This invention relates to methods and products for the diagnosis, surveillance, prevention, and treatment of influenza A virus infections in animals and humans. More particularly, the invention relates to antibodies and related binding proteins for the detection, prevention and treatment of influenza A viruses. The monoclonal antibodies and related binding proteins of the invention are useful for the treatment of the highly pathogenic H5 subtypes of avian influenza virus (AIV). | 10-20-2011 |
| 20110247099 | GENETIC TRANSFORMATION OF JATROPHA CURCAS - The present invention relates to methods for the regeneration and | 10-06-2011 |
| 20110124107 | METHOD OF HIGH FREQUENCY REGENERATION OF SORGHUM - The present invention relates generally to the regeneration of | 05-26-2011 |
| 20110117652 | SOMATIC EMBRYOGENESIS OF JATROPHA CURCAS FROM OVULES - The present invention relates to the field of somatic embryo production, particularly to methods for somatic embyrogenesis of | 05-19-2011 |
| 20110053142 | Binding Protein and Epitope-Blocking Elisa for the Universal Detection of H5-Subtype Influenza Viruses - Monoclonal antibodies and related binding proteins specific to influenza H5 subtype HA protein can be used in serological diagnosis of influenza H5 infection in mammalian and avian serum samples, including human serum samples. Each antibody reacts strongly with a wide variety of strains of H5 subtype and does not show cross-reactivity with non-H5 influenza subtypes. | 03-03-2011 |
| 20110008871 | Production of Homogeneous Cell Line Highly Permissive To Porcine Circovirus Type 2 (PCV2) Infection - Continuous cell lines that are highly permissive to infection by porcine circovirus type 2 (“PCV2”) are described. PCV2 is the causal agent of post-weaning multi-systemic wasting syndrome (“PMWS”) in pigs. PMWS has emerged as a major disease that poses a significant threat to the economics of global swine industry. The highly permissive cell lines of this invention provide efficient and reliable sources of PCV2 for use in development of vaccines, therapies and diagnostic agents for PMWS. | 01-13-2011 |
| 20110003278 | H5 Subtype-Specific Binding Proteins Useful for H5 Avian Influenza Diagnosis and Surveillance - The invention provides monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes of avian influenza virus (“AIV”). The monoclonal antibodies and related binding proteins are useful for the detection of H5 subtypes of AIV, including the pathogenic H5N1 subtypes. Virus may be detected in formalin preserved, paraffin embeded specimens as well as frozen specimens and biological fluids. Accordingly, the invention provides means for the diagnosis and surveillance of dangerous viral infections. | 01-06-2011 |
| 20100304488 | REGENERATION AND MASS PROPAGATION OF JATROPHA CURCAS THROUGH SOMATIC EMBRYOGENESIS - The present invention relates to the field of somatic embryo production, particularly to methods for the regeneration of | 12-02-2010 |
| 20100299787 | N-TERMINAL XA27 SIGNAL ANCHOR AND ITS USE FOR LOCALIZATION OF FUSION PROTEINS - The present application is directed to a functional signal anchor that localizes a fusion protein to the apoplast of vascular elements in plants. The signal anchor is useful for engineering secretory proteins to the cell wall and or/apoplast of plant cells. The signal anchor is also useful for producing secretory proteins in transgenic plant cells in a bioreactor. | 11-25-2010 |
| 20100297126 | Monoclonal Antibodies Specific to Hemagglutinin from Influenza Virus H5-Subtype and Uses Thereof - Monoclonal antibodies and related binding proteins that are specific for conformational epitopes of avian influenza virus K5 subtype hemagglutinin glycoprotein are provided. The antibodies can be used for the detection and treatment of H5 subtype AIV in specimens. | 11-25-2010 |
| 20100269182 | LEXA-BASED CHEMICAL-INDUCIBLE GENE EXPRESSION SYSTEM FOR USE IN TRANSGENIC ANIMALS - The present invention relates generally to chemical-inducible system and to methods of use in transgenic animals. More specifically, the present invention relates to a chimeric transcription factor that binds to a ligand and functions in ligand-dependent manner to induce expression of genes of interest under the control of a synthetic operator-promoter sequence. The expression of genes of interest can be tightly controlled by adding or removing the ligand. | 10-21-2010 |
| 20100266585 | Monoclonal Antibodies Specific to Hemagglutinin and Neuraminidase from Influenza Virus H5-Subtype or N1-Subtype and Uses Thereof - Monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes or neuraminidase glycoprotein of N1 subtypes of avian influenza virus (AIV) are provided. The monoclonal antibodies and related binding proteins are useful for the detection of H5 and N1 subtypes of AIV, including H5N1 subtypes and provide means for the diagnosis, surveillance and treatment of dangerous viral infections. | 10-21-2010 |
| 20100162438 | INDUCTION OF Xa27 BY THE avrXa27 GENE IN RICE CONFERS BROAD-SPECTRUM RESISTANCE TO Xanthomonas oryzae pv. oryzae AND ENHANCED RESISTANCE TO Xanthomonas oryzae pv. oryzicola - The present invention generally provides a method to generate broad-spectrum resistance to bacterial blight disease in plants. More specifically, the present invention provides a method to generate broad-spectrum resistance to | 06-24-2010 |
| 20090220961 | Fluorescent Primer System For Detection Of Nucleic Acids (Q Priming) - The present invention is directed to a self-quenching primer comprising; a fluorophore that can be quenched by guanine; an oligonucleotide sequence that forms a hairpin; an oligonucleotide that is a target specific sequence and; use in amplification reactions, particularly in polymerase chain reactions, during which the fluorophore is released thereby emitting fluorescence. | 09-03-2009 |
| 20090131272 | TRANSPOSITION OF MAIZE AC/DS ELEMENTS IN VERTEBRATES - The present invention is directed to the use of the maize Ac/Ds transposable elements in vertebrates. | 05-21-2009 |
| 20090099088 | System for Inhibiting Pathogenicity in the Rice-Blast Fungus Magnaporthe Grisea | 04-16-2009 |
| 20080289054 | Fish Cancer Model - The present invention is directed to fish whose genome has integrated therein an oncogenic nucleic acid operably linked to a promoter. Methods of making the fish and methods for their use are also provided. The fish may advantageously be utilized in methods of screening for drugs or agents that modulate oncogene-mediated neoplastic or hyperplastic transformation, or that modulate sensitivity to chemotherapy or radiation therapy. Immortal tumor cells lines, methods of making immortal tumor cell lines and methods of their use are also provided. | 11-20-2008 |
