System Biosciences, LLC Patent applications |
Patent application number | Title | Published |
20140273226 | CRISPR/CAS SYSTEMS FOR GENOMIC MODIFICATION AND GENE MODULATION - The invention relates to engineered CRISPR/Cas9 systems for genomic modification and regulation of gene expression in mammalian cells. The specification describes the design and validation of polynucleotides encoding the | 09-18-2014 |
20140273037 | COMPOSITIONS AND METHODS DIRECTED TO CRISPR/CAS GENOMIC ENGINEERING SYSTEMS - The invention relates to engineered CRISPR/Cas9 systems for genomic modification in mammalian cells. The present specification describes the design and testing of a polynucleotide encoding the | 09-18-2014 |
20130337440 | METHODS FOR MICROVESICLE ISOLATION AND SELECTIVE REMOVAL - The invention relates to compositions and methods for isolation of microvesicles produced by mammalian cells. These microvesicles, known as extracellular microvesicles or circulating microvesicles, are isolated from sample materials such as body fluids, or from cell culture media that has been used to culture and maintain mammalian cells in vitro. The isolation of microvesicles as described herein results in purification and concentration of the microvesicles. | 12-19-2013 |