SYNAPSE B.V. Patent applications |
Patent application number | Title | Published |
20140296146 | Thermostable Inhibitors of Activation of the Blood Clotting System Through Contact with Foreign Surfaces - The present invention relates to the field of blood clotting. Specifically, the invention relates to particular inhibitors of artificial activation of the blood clotting process through contact with foreign surfaces. | 10-02-2014 |
20110045512 | TIME-COURSE MEASUREMENT OF ENZYMATIC ACTIVITY CORRECTED FOR IMPACTS OF DISTURBANCES RELATING TO THE REACTION OF THE ENZYME WITH A SUBSTRATE - A method of determining the course of enzyme activity that is variable in time, wherein the activity is probed by conversion of a substrate of the enzyme, includes, in a selected test set up and for a determined substrate of the enzyme, determining the velocity of signal production (dF | 02-24-2011 |
20090311730 | Measuring thrombin activity in whole blood - The invention relates to a method for in vitro determining thrombin activity in a sample wherein the sample is a blood sample and thrombin generation is measured by the steps of: —contacting a layer of said sample with a fluorogenic substrate of thrombin, wherein said layer has a thickness within a range of 0.05 to 5 mm and a surface within a range of 10 to 500 mm2; —allowing thrombin to generate in said sample; —measuring the fluorescence emitted from the surface of the layer, by the fluorescent group released from the fluorogenic substrate as a result of enzymatic action of generated thrombin on said fluorogenic substrate. | 12-17-2009 |