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SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER

SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER Patent applications
Patent application numberTitlePublished
20120076795Anti-PECAM Therapy, Compositions, Methods, and Uses - The disclosure relates to the discovery that systemic administration of an antibody that binds to PECAM-1 increases body weight while suppressing the metastatic spread of a wide variety of different tumor types which are typically fatal in humans. This discovery provides a basis for the generation of novel treatments and medicaments, wherein provision of a systemic dosage of anti-pECAM-1 antibody or a proxy that provides the same functional result is administered to a patient suffering from cancer cachexia and/or metastasis associated with end-stage cancer03-29-2012
20110184009CAMPTOTHECIN DERIVATIVES AS CHEMORADIOSENSITIZING AGENTS - Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.07-28-2011