| Streck, Inc. Patent applications |
| Patent application number | Title | Published |
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| 20120129147 | METHOD OF PREPARING CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS - By way of summary, the present invention meets some or all of the above needs by providing in a first aspect a method comprising contacting red blood cells in a suspension medium containing mannose under conditions such that the concentration of S-Alc glycated hemoglobin is increased to greater than about 6 percent by weight of the hemoglobin in the red blood cells. Preferably the suspension medium is an aqueous suspension medium. In preferred embodiments, the method is performed at about ambient temperature, 18° C. to about 23° C. | 05-24-2012 |
| 20120122073 | CIS DI-AHL MODIFIED CONTROLS FOR GLYCATED HEMOGLOBIN S-A1C DERIVED FROM HEALTHY BLOOD CELLS - The invention is composition comprising red blood cells in an aqueous suspension medium and one or more cis di-ahls; wherein more than 6 percent by weight of the hemoglobin in the red blood cells is S-Alc glycated hemoglobin. In another embodiment, the invention is a method comprising contacting red blood cells in a suspension medium having a concentration of S-Alc glycated hemoglobin of greater than 6 percent by weight of the hemoglobin in the red blood cells with a sufficient amount of one or more cis di-ahls such that the concentration of S-Alc glycated hemoglobin in resulting composition as measured by high pressure liquid chromatography, immunoassay and boronate affinity methods is consistent. | 05-17-2012 |
| 20110300608 | NUCLEIC ACID ISOLATION IN PRESERVED WHOLE BLOOD - A method for isolating nucleic acids is disclosed, wherein a sample having nucleic acid containing starting material is fixed, lysed, and treated to remove unwanted contaminants. The initial fixing of the sample aids in maintaining the structure and integrity of the isolated DNA and reduces the incidence of end product contaminants and DNA shearing. | 12-08-2011 |
| 20110111410 | STABILIZATION OF RNA IN INTACT CELLS WITHIN A BLOOD SAMPLE - A method for preserving and processing nucleic acids located within a blood sample is disclosed, wherein a blood sample containing nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the integrity and amount of cellular nucleic acids that can be identified and tested while avoiding contamination of the isolated nucleic acids with cell-free nucleic acids. | 05-12-2011 |
| 20110110975 | INACTIVATED VIRUS COMPOSITIONS AND METHODS OF PREPARING SUCH COMPOSITIONS - The present invention is a composition comprising a live virus having an infectious component and a plurality of surface antigens in contact with a formaldehyde donor agent having a molecular weight that is less than about 400 g/mol. The present invention further provides a method for deactivating a live virus having an infectious component and a plurality of surface antigens, comprising the steps of: a) providing a live virus having an infectious component and a plurality of surface antigens; and b) contacting the virus with a formaldehyde donor agent having a molecular weight that is greater than about 50 g/mol and less than about 400 g/mol for a period of time (e.g., at least about 12 hours) sufficient for de-activating the infectious component with the formaldehyde donor agent and for preserving at least a portion of the surface antigens to form a deactivated virus. In another embodiment the invention is a method of preparing a composition useful as a vaccine comprising the abovementioned steps in combination with the step of c) mixing a non-toxic effective amount, for inducing an immune response in a subject to which the vaccine is administered, of the deactivated virus with a pharmaceutically acceptable carrier. Preferably the composition containing a pharmaceutically acceptable carrier is useful in, or as, a vaccine composition. | 05-12-2011 |
| 20110053208 | BIOLOGICAL SAMPLE IDENTIFICATION SYSTEM - The present invention contemplates a handling device for a biological specimen. The handling device includes a substrate with at least one crease that divides the substrate into a handle portion and a receiving portion that includes an aperture having a perimeter that is configured so that it receives a container having a cover that includes a biological specimen for testing, while resisting pull-through of the container relative to the substrate. | 03-03-2011 |
| 20100317107 | METHOD AND DEVICE FOR COLLECTING AND PRESERVING CELLS FOR ANALYSIS - The claimed subject matter comprises a device to collect and preserve cells comprising of: (1) a collection container comprised of a tube having an open end and a closed end, a closure in the open end of the tube, a vacuum drawn to a predetermined level inside the container; and (2) compounds including an anticoagulant agent and a fixative agent, wherein the compounds are in a sufficient amount to preserve said cells” original morphology and antigenic sites without significant dilution of said cells, and thereby allowing said cells to be directly analyzed by a flow cytometer without further treatment. The claimed subject matter further comprises of a method of making a collection device for cells comprising of: (1) providing a tube having an open end and a closed end; (2) preloading compounds including: an anticoagulant agent, and a fixative agent into the tube, wherein the compounds are in a sufficient amount to preserve the cells” original morphology and antigenic sites without significant dilution of the cells, and thereby allowing the cells to be directly analyzed by a flow cytometer without further treatment; (3) inserting a closure into the open end of the tube; and (4) drawing a vacuum inside the tube to a predetermined level to form the collection device. | 12-16-2010 |
| 20100291536 | SAMPLE PROCESSING CASSETTE, SYSTEM, AND METHOD - The present invention provides a method and device for collecting treating and analysis of biological or chemical material by introducing a source material into a specimen container, transferring the source material to a processing device and thermally, chemically and/or mechanically treating the source material to alter at least one constitutive characteristic of the source material and to release or create a target material from the source material. | 11-18-2010 |
| 20100288059 | SPECIMEN CONTAINER, SYSTEM, AND METHOD - This invention relates to the collection and handling of biological or chemical specimens. The invention provides a device and a method for collecting and preparing patient samples, such as sputum, to be used in downstream diagnostics tests. The invention reduces the handling and exposure of healthcare workers to the sample by the use of a bag in which hermetic seals are utilized to separate sample aliquots. | 11-18-2010 |
| 20100209930 | PRESERVATION OF CELL-FREE NUCLEIC ACIDS - A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the amount of cell-free nucleic acids that can be identified and tested while maintaining the structure and integrity of the nucleic acids. | 08-19-2010 |
| 20100184069 | PRESERVATION OF FETAL NUCLEIC ACIDS IN MATERNAL PLASMA - A method for preserving and processing fetal nucleic acids located within maternal plasma is disclosed, wherein a sample of maternal blood containing fetal nucleic acids is treated to reduce both cell lysis of the maternal blood cells and deoxyribonuclease (DNase) and ribonuclease (RNase) activity within the fetal nucleic acids. The treatment of the sample aids in increasing the amount of fetal nucleic acids that can be identified and tested while maintaining the structure and integrity of the fetal nucleic acids. | 07-22-2010 |
| 20100167271 | METHOD FOR SCREENING BLOOD USING A PRESERVATIVE THAT MAY BE IN A SUBSTANTIALLY SOLID STATE FORM - Methods and devices useful for screening a blood product for a transfusion, pursuant to which leukocytes in drawn whole blood are contacted with a formaldehyde releaser screening preservative so that the presence of any residual leukocytes can be screened. A substantially solid state form preservative for one or more blood components (e.g., leukocytes) and use thereof is also described. | 07-01-2010 |
| 20100086962 | HEMATOLOGY CONTROLS AND METHODS - An integrated hematology control and methods for making the same, including a first cellular component derived from a plurality of processed animal red blood cells other than human blood cells and a second cellular component derived from a plurality of processed animal red blood cells other than human blood cells and a plurality of human blood cells, wherein the control simulates erythroblasts and white blood cells of a human blood sample on an automated blood analyzer. | 04-08-2010 |
| 20100047905 | SIMULATED BLOOD COMPONENTS AND METHODS - A control and a cellular fraction for use therein and methods for making the same, including a first cellular component including a plurality of a first group of processed animal red blood cells other than human blood cells; a second cellular component including a plurality of a second group of processed animal red blood cells other than human blood cells; a third cellular component including a plurality of a third group of processed animal red blood cells other than human blood cells; wherein one or more of the first second and third cellular components include a nucleus; and the control simulates erythroblasts of a human blood sample on an automated blood analyzer that analyzes blood cells using impedance, optical measurements or both. | 02-25-2010 |
| 20090081678 | NUCLEIC ACID ISOLATION IN PRESERVED WHOLE BLOOD - A method for isolating nucleic acids is disclosed, wherein a sample having nucleic acid containing starting material is fixed, lysed, and treated to remove unwanted contaminants. The initial fixing of the sample aids in maintaining the structure and integrity of the isolated DNA and reduces the incidence of end product contaminants and DNA shearing. | 03-26-2009 |
| 20080286748 | BLOOD COLLECTION TUBE WITH SURFACTANT - Improvements in blood collection and testing. In one aspect, an improved method of manufacturing a blood collection tube, particularly illustrated for use in sedimentation rate testing, including providing an elongated glass tube with an open first end for receiving a venipuncture blood sample of at least 1 ml, formed with a closed end opposite the first end; and applying to a substantial portion of the receptacle a containment barrier. The improvements also pertain to resulting blood collection tubes, additives for blood collection tubes that permit reliable sedimentation test data after 8 hours from the blood draw, and methods of administering health care using the aforenoted tubes, additives or both. | 11-20-2008 |
| 20080254543 | SIMULATED BLOOD COMPONENTS AND METHODS - A control and a cellular fraction for use therein and methods for making the same, including a first cellular component including a plurality of a first group of processed animal red blood cells other than human blood cells; a second cellular component including a plurality of a second group of processed animal red blood cells other than human blood cells; a third cellular component including a plurality of a third group of processed animal red blood cells other than human blood cells; wherein one or more of the first second and third cellular components include a nucleus; and the control simulates erythroblasts of a human blood sample on an automated blood analyzer that analyzes blood cells using impedance, optical measurements or both. | 10-16-2008 |
