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STICHTING TER BEVORDERING VAN DE FARMACODYNAMIEK

STICHTING TER BEVORDERING VAN DE FARMACODYNAMIEK Patent applications
Patent application numberTitlePublished
20110229902METHOD FOR DETERMINING THE RESISTANCE STATUS OF FUNGI AND YEASTS, IN PARTICULAR OF ASPERGILLUS FUMIGATUS - The invention relates to a method for determining the resistance status of fungi and yeasts in a body sample of a patient suspected of having an invasive infection, comprising the steps of isolating DNA from a body sample of the patient, identifying mutations in a gene of the fungus or yeast, and correlating the resistance status of the fungus or yeast to the mutations found, wherein the body sample is blood or a blood derivative or a sample of an organ, and is in particular serum. Suitably, the method is performed in closed-tube format. The method of the invention is particularly suitable when the fungus of which the resistance status is to be determined is 09-22-2011