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Stichting Dienst Landbouwkundig Onderzoek

Stichting Dienst Landbouwkundig Onderzoek Patent applications
Patent application numberTitlePublished
20120036596MAMMALIAN-TYPE GLYCOSYLATION IN PLANTS BY EXPRESSION OF NON-MAMMALIAN GLYCOSYLTRANSFERASES - The present invention relates to non-mammalian β-1,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian β-1,4-galacto-syltransferase and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian β-1,4-galactosyltransferases.02-09-2012
20120021930Multiplex Nucleic Acid Detection - The present invention relates to a novel multiplex detection of nucleic acid targets in a sample. This is accomplished by using novel padlock probes which contain a unique cleavage site for linearization and a first member of a binding pair for isolation of the padlock probe from the sample. Three different designs of the padlock probes are described and examples are shown for ligation, amplification and qualitative and quantitative detection. The combination of these features gives a fast, accurate and specific multiplex detection assay01-26-2012
20120011600OPTIMIZING GLYCAN PROCESSING IN PLANTS - The invention is directed to methods for optimizing glycan processing in organisms (and in particular, plants) so that a glycoprotein having complex type bi-antennary glycans and thus containing galactose residues on both arms and which are devoid of (or reduce in) xylose and fucose can be obtained. The invention is further directed to said glycoprotein obtained and host system comprising said protein.01-12-2012
20110302823ATTRACTANT COMPOSITIONS FOR WEEVILS OF THE GENUS OTIORHYNCHUS AND USES THEREOF - The present invention relates to formulations of volatile organic compounds having effects on 12-15-2011
20110159559METHOD FOR THE COMBINED PRODUCTION OF BUTANOL AND HYDROGEN - The invention relates to a process for the combined production of butanol and hydrogen from biomass, comprising the steps of fermenting biomass to obtain butanol in a first reaction mixture; removing the butanol and hydrogen from the first reaction mixture to obtain effluent; and using the effluent as a substrate in a second reaction mixture in a process using low substrate concentrations, in particular a hydrogen production process. Preferably, the process using low substrate concentrations is a hydrogen production process and at least part of the end products of the hydrogen production process is removed from the second reaction mixture for obtaining an effluent that comprises organic acid, which effluent is returned to the first reaction mixture.06-30-2011
20110030108MAMMALIAN-TYPE GLYCOSYLATION IN PLANTS - The invention relates to the field of glycoprotein processing in transgenic plants used as cost efficient and contamination safe factories for the production of recombinant biopharmaceutical proteins or pharmaceutical compositions comprising these. The invention provides a plant comprising a functional mammalian enzyme providing N-glycan biosynthesis that is normally not present in plants, said plant additionally comprising at least a second mammalian protein or functional fragment thereof that is normally not present in plants.02-03-2011

Patent applications by Stichting Dienst Landbouwkundig Onderzoek