| Stanford University Patent applications |
| Patent application number | Title | Published |
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| 20120108460 | NON-INVASIVE FETAL GENETIC SCREENING BY SEQUENCING ANALYSIS - The invention provides a non-invasive technique for the differential detection of multiple genotypes and/or mutations for a plurality of target genes in a biological sample containing genetic material from different genomic sources. Methods are conducted using multiplex amplification of a plurality of target sequences from the biological sample, and sequencing is used to detect and enumerate genetic mutations and chromosomal abnormalities at the single nucleotide level. | 05-03-2012 |
| 20120029911 | METHOD AND SYSTEM FOR DISTRIBUTED AUDIO TRANSCODING IN PEER-TO-PEER SYSTEMS - A method for streaming audio data in a network, the audio data having a sequence of samples, includes encoding the sequence of samples into a plurality of coded base bitstreams, generating a plurality of enhancement streams, and transmitting the coded base bitstreams and the enhancement bitstreams to a receiver for decoding. Each of the enhancement bitstreams is generated from one of a plurality of non-overlapping portions of the sequence of samples. | 02-02-2012 |
| 20110301180 | Reducing Platelet Activation, Aggregation and Platelet-Stimulated Thrombosis or Blood Coagulation by Reducing Mitochondrial Respiration - It has been discovered that inhibiting mitochondrial respiration in platelets reduces platelet activation or platelet aggregation. Certain heterocyclic compounds significantly reduced one or more platelet functions including clumping, sticking or platelet-stimulated clotting. Thus diseases or disorders mediated by inappropriately high levels of platelet activation or platelet aggregation can be treated by administering a therapeutically effective amount of a heterocyclic compound or nonheterocyclic mitochondrial inhibitor that significantly reduces one or more platelet functions including clumping, sticking or platelet-stimulated clotting, preferably in a reversible manner. | 12-08-2011 |
| 20110286627 | METHOD AND APPARATUS FOR TRACKING AND RECOGNITION WITH ROTATION INVARIANT FEATURE DESCRIPTORS - Various methods for tracking and recognition with rotation invariant feature descriptors are provided. One example method includes generating an image pyramid of an image frame, detecting a plurality of interest points within the image pyramid, and extracting feature descriptors for each respective interest point. According to some example embodiments, the feature descriptors are rotation invariant. Further, the example method may also include tracking movement by matching the feature descriptors to feature descriptors of a previous frame and performing recognition of an object within the image frame based on the feature descriptors. Related example methods and example apparatuses are also provided. | 11-24-2011 |
| 20110266550 | METHOD OF FORMING OF A SEMICONDUCTOR FILM, METHOD OF MANUFACTURE OF A SEMICONDUCTOR DEVICE AND A SEMICONDUCTOR DEVICE - This invention provides a method of forming semiconductor films on dielectrics at temperatures below 400° C. Semiconductor films are required for thin film transistors (TFTs), on-chip sensors, on-chip micro-electromechanical systems (MEMS) and monolithic 3D-integrated circuits. For these applications, it is advantageous to form the semiconductor films below 400° C. because higher temperatures are likely to destroy any underlying devices and/or substrates. This invention successfully achieves low temperature growth of germanium films using diboran. First, diboran gas is supplied into a reaction chamber at a temperature below 400° C. The diboran decomposes itself at the given temperature and decomposed boron is attached to the surface of a dielectric, for e.g., SiO | 11-03-2011 |
| 20110218485 | Insertion Indicator for Needle - A method and apparatus are provided for a fluid level insertion indicator that provides immediate feedback to a surgeon by draining when a tip of a needle has entered a body lumen, such as peritoneal cavity. An apparatus includes a handle connected to a hollow needle and a hollow stylet that extends through the hollow needle and has a blunt distal end that includes an opening for passing fluid. A spring biases the stylet to extend past the sharp distal end of the needle absent resistance by tissue against the stylet. An at least partially translucent pressure chamber configured to hold a quantity of fluid under pressure is connected to the proximal end of the stylet. The pressure chamber and stylet form a conduit for passing fluid through the opening in the blunt distal end when the stylet extends past the sharp distal end of the hollow needle. | 09-08-2011 |
| 20110200529 | ACTIVATABLE BIOLUMINESCENT PROBE SYSTEM AND METHOD OF USE THEREOF - A method of use of an activatable bioluminescent probe system includes: providing a bioluminescent protein and a quencher in a reaction environment; modifying a ligand between the quencher and the bioluminescent protein using a ligand interacting molecule; adding a bioluminescence initiating molecule to the reaction environment; and measuring light originating from the interaction between the bioluminescent protein and the bioluminescence initiating molecule. | 08-18-2011 |
| 20110169678 | HIGH FIDELITY, RADIATION TOLERANT ANALOG-TO-DIGITAL CONVERTERS - Techniques for an analog-to-digital converter (ADC) using pipeline architecture includes a linearization technique for a spurious-free dynamic range (SFDR) over 80 deciBels. In some embodiments, sampling rates exceed a megahertz. According to a second approach, a switched-capacitor circuit is configured for correct operation in a high radiation environment. In one embodiment, the combination yields high fidelity ADC (>88 deciBel SFDR) while sampling at 5 megahertz sampling rates and consuming <60 milliWatts. Furthermore, even though it is manufactured in a commercial 0.25-μm CMOS technology (1 μm=12 | 07-14-2011 |
| 20110095763 | GEOLOGIC MAPPING USING LIGHTNING - A method and apparatus includes detecting lightning induced electromagnetic pulses and determining a physical property of an underground structure based on the lightning induced electromagnetic pulses. In some embodiments, an apparatus includes an antenna, a low noise amplifier, a processor, cable, and a transmitter. The antenna includes three substantively perpendicular loops of electrical conductors. The processor is configured to condition the amplified signal. The cable is about 100 meters in length and connects the low noise amplifier to the processor. The transmitter is configured to send conditioned data to a data aggregation system. | 04-28-2011 |
| 20110093033 | ELICITING ANALGESIA BY TRANSCRANIAL ELECTRICAL STIMULATION - A method of eliciting analgesia in a human subject by Transcranial Electrical Stimulation (TCES, herein “TES”) is provided. Electrodes secured to the skin of the subject's head at particular sites provide an electrical current that includes a direct current combined with rectangular AC current pulses delivered at a particular frequency of between 10 and 100 Hz. In an embodiment the total current transmitted, a sum of the DC component and a Mean Absolute Deviation (MAD) of the current pulses, has a value between 0.2 and 20 mA. The method is used to produce analgesia during perioperative period, surgery and the post-operative procedure. It can also be used for treating acute chronic pain and a wide variety of other conditions. | 04-21-2011 |
| 20110039094 | Methods Of Bonding Optical Structures, Bonding And Silylation Of Optical Structures, Bonded Optical Structures, And Silylated Bonded Optical Structures - Methods of bonding optical structures, bonded optical structures, silylated bonded optical structures, and the like, are disclosed. | 02-17-2011 |
| 20100301928 | LOW NOISE, LOW POWER SUBSAMPLING RECEIVER - Techniques for a receiver includes a low noise amplifier, a Q-enhanced bandpass filter on a chip, and an analog to digital converter (ADC) at a sub-sampling speed suitable for an intermediate frequency (IF) signal. In some embodiments, a temperature compensation circuit is included. The receiver has an effective noise level less than 7 dB. In some embodiments a 1-bit ADC is used. In some of these embodiments, one or more switches in the ADC are inverted to cancel charge injection. | 12-02-2010 |
| 20100280219 | OLIGOCARBONATE MOLECULAR TRANSPORTERS - A cyclic carbonate monomer, including: | 11-04-2010 |
| 20100226575 | METHOD AND APPARATUS FOR REPRESENTING AND IDENTIFYING FEATURE DESCRIPTIONS UTILIZING A COMPRESSED HISTOGRAM OF GRADIENTS - A method, apparatus and computer program product may be provided for generating a plurality of compressed feature descriptors that can be represented by a relatively small number of bits, thereby facilitating transmission and storage of the feature descriptors. A method, apparatus and computer program product may also be provided for permitting a compressed representation of a feature descriptor to be compared with a plurality of compressed representations of feature descriptors of respective predefined features. By permitting the comparison to be performed utilizing compressed representations of feature descriptors, a respective feature descriptor may be identified without having to first decompress the feature descriptor, thereby potentially increasing the efficiency with which feature descriptors may be identified. | 09-09-2010 |
| 20100176465 | METHOD OF EPITAXIALLY GROWING PIEZORESISTORS - A method of forming a device with a piezoresistor is disclosed herein. In one embodiment, the method includes providing a substrate, etching a trench in the substrate to form a vertical wall, growing a piezoresistor layer epitaxially on the vertical wall, and separating the vertical wall from an underlying layer of the substrate that extends along a horizontal plane such that the piezoresistor layer is movable with respect to the underlying layer within the horizontal plane. | 07-15-2010 |
| 20100036208 | METHOD AND APPARATUS FOR IN-VIVO PHYSIOLOGICAL MONITORING - A method is provided that includes providing a monitoring apparatus including one or more modules within a target cavity or lumen of a body. The one or more modules are provided within the target cavity or lumen in a first state in which the monitoring apparatus is configured to remain within the target cavity or lumen. The method further includes monitoring physiological conditions of the body using one or more sensors within the one or more modules, and providing the one or more modules in a second state in which the monitoring apparatus is configured to exit the target cavity or lumen. | 02-11-2010 |
| 20100015058 | RADIOLABELED BBN-RGD HETERODIMERS FOR CANCER TARGETING - The present disclosure encompasses heterodimeric compositions for delivering radiolabeled and other ligands to a cell or tissue, and particularly to compositions and methods of use thereof for targeting and imaging cells and tissues expressing both an integrin and gastrin-releasing peptide receptor, in particular prostate cancer cells. The disclosure, therefore, firstly encompasses compositions that can comprise a heterodimeric probe comprising a first peptide domain comprising a moiety capable of selectively binding to an integrin; a second peptide domain comprising a moiety capable of selectively binding to a gastrin-releasing peptide receptor; a linker connecting the first peptide domain and the second peptide domain; and a prosthetic group. The first peptide domain comprises at least one tripeptide comprising the amino acid sequence of arginine-glycine-aspartate, and the second domain can be the peptide bombesin(7-14). The prosthetic group can be the fluoride isotope | 01-21-2010 |
| 20100009400 | METHODS OF STUDYING A BIOMARKER, AND METHODS OF DETECTING A BIOMARKER - Embodiments of the present disclosure provide for methods of studying (e.g., detecting, localizing, and/or quantifying) biomarker(s) and the like. | 01-14-2010 |
| 20090306454 | Devices and Methods for Stimulation of Tissue - Devices, systems and methods are provided for directly stimulating tissues, particularly muscle tissues, to modulate muscle contractions (i.e. provide reanimation of the muscle or to suppress undesired muscle contractions). Reanimation of muscles may be desired when damage to the brain, nervous system or neuromuscular junctions have occurred, causing a muscle tissue to lack sufficient motor control. Suppression of muscle contractions may be desired in situations of pathologically hyperactive muscles, such as in conditions of muscle spasm (e.g. blepharospasm and hemifacial spasm) or muscle dystonia. Direct stimulation is achieved by delivering a chemical agent directly to the muscle tissue, particularly the motor end plate, bypassing the nerves and neuromuscular junctions which may be damaged or diseased. Implanted hybrid chemical and electromagnetic stimulation devices can modulate muscle contraction in response to signals from a controller. | 12-10-2009 |
| 20090075313 | Split protein fragments, split protein systems, methods of making split protein systems, and methods of using split protein systems - Split protein herpes simplex virus type 1 thymidine kinase [HSV1-TK or TK] TK fragments, split protein TK systems, methods of imaging protein-protein interactions, methods of cellular localization of proteins, methods of evaluating protein translocation and trafficking, and the like, are provided. In addition, the present disclosure includes compositions used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging) in vivo and in vitro. | 03-19-2009 |
| 20090053690 | SURFACE CHEMISTRY AND DEPOSITION TECHNIQUES - Surface chemistries for the visualization of labeled single molecules (analytes) with improved signal-to-noise properties are provided. To be observed, analyte molecules are bound to surface attachment features that are spaced apart on the surface such that when the analytes are labeled adjacent analytes are optically resolvable from each other. One way to express this concept is that binding elements should be spaced apart such that the Guassian point spread functions of adjacent labels do not overlap. Another way of expressing this concept is that the surface binding elements should be spaced apart by a distance equal to at least the diffraction limit for an optical label attached to the bound analytes. | 02-26-2009 |
| 20080267882 | Imaging compounds, methods of making imaging compounds, methods of imaging, therapeutic compounds, methods of making therapeutic compounds, and methods of therapy - Embodiments of the present disclosure provide for RGD compounds that include a multimeric RGD (arginine-glycine-aspartic acid (Arg-Gly-Asp)) peptide, methods of making the RGD compound, pharmaceutical compositions including RGD compound, methods of using the RGD compositions or the pharmaceutical compositions including RGD compositions, methods of diagnosing and/or targeting angiogenesis related disease and related biological events, kits for diagnosing and/or targeting angiogenesis related disease and related biological events, and the like. In addition, the present disclosure includes compositions used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging) of the RGD compounds in vivo. | 10-30-2008 |
| 20080241843 | Single-cell analysis systems, methods of counting molecules in a single-cell, cylindrical fluorescence detection systems - Embodiments of the present disclosure provide for single-cell analysis systems, methods of detecting target components in a single cell, cylindrical fluorescence detection systems, and the like. | 10-02-2008 |
