| St. Marianna University School of Medicine Patent applications |
| Patent application number | Title | Published |
|---|
| 20110202065 | BONE CEMENT INJECTION NEEDLE - A bone cement injection needle comprises: a hollow outer needle; an outer needle hub affixed to the base end part of the outer needle; an inner needle that can be slidably inserted into the hollow part of the outer needle; and an inner needle hub affixed to the base end part of the inner needle. The outer needle comprises a first side hole located near the tip; a second side hole located near the base end part; and a depressurization passage which connects the first side hole and the second side hole. | 08-18-2011 |
| 20110027881 | PRODUCTION METHOD OF IMMUNE CELLS - A production method of T cells is disclosed which includes generating iPS cells from immune cells and differentiating the iPS cells into desired immune cells. In this method, 4 different genes Oct4, Sox2, Klf4 and c-Myc are introduced into immune cells for generation of iPS cells, and the iPS cells are then differentiated into immune cells by coculture with OP9 cells. Source immune cells are taken from a patient, and the produced desired immune cells are injected into the patient for medical treatment. | 02-03-2011 |
| 20100330014 | COMPOSITION FOR EXTERNAL APPLICATION ON SKIN, AND SKIN-WHITENING COSMETIC - An object of the present invention is to provide a composition for external application on the skin containing hydroquinone as an active ingredient, which has an excellent skin-whitening activity and reduced side effects. The composition for external application on the skin of the present invention as a means for achieving the object is characterized by containing hydroquinone or a derivative thereof compounded with a lyotropic liquid crystal. | 12-30-2010 |
| 20100113557 | METHOD FOR PREVENTION OF TUMOR - The present invention provides a method for inhibiting a tumor, which comprises suppressing the expression of HERC2. In one embodiment of the present invention, the suppression of HERC2 is induced by the expression of BRCA1. | 05-06-2010 |
| 20100068702 | Method for Detecting Disease-Related Marker Using Gastric Mucosal Lavage Fluid - The invention relates to a sample containing a gastric mucosa lavage fluid collected from a subject who has received a gastric mucus removal treatment and a method for detecting a disease-related marker using the same. By using the sample of the invention, the disease-related marker can be detected conveniently, less invasively, highly sensitively and highly accurately. | 03-18-2010 |
| 20100040599 | THERAPEUTIC AGENT FOR RHEUMATOID ARTHRITIS - When C60 was added to synovial fibroblasts, infiltrating lymphocytes, and macrophages, and the inflammatory cytokine production level was measured, the inflammatory cytokine production level was significantly suppressed in all cells. Furthermore, when C60 was added to osteoclast precursor cells and cultured in the presence of osteoclast differentiation-inducing factors, a certain concentration or more of C60 suppressed their differentiation into osteoclasts. Observation of the effect of C60 addition on bone resorption showed that C60 suppressed bone resorption by osteoclasts. In addition, the use of arthritis model animals confirmed in vivo that C60 suppressed inflammatory symptoms, as well as bone resorption and bone destruction by osteoclasts. C60 is effective for treating arthritic diseases such as rheumatoid arthritis through its effects of suppressing osteoclast differentiation, bone resorption, and inflammatory cytokines. | 02-18-2010 |
| 20090311221 | BIOMATERIALS FOR REGENERATIVE MEDICINE - It was examined whether a cartilage-like tissue is formed under various reaction conditions using cartilage matrix components: glycosaminoglycan, proteoglycan, and collagen. The present inventors have discovered that proteoglycan bound to glycosaminoglycan through self-organization form an aggregate when the glycosaminoglycan was reacted with proteoglycan under specific concentrations and pH, and that a mesh structure composed of collagen fibers was constructed through self-organization using the aggregates as a skeleton when the aggregates were reacted with collagen molecules. | 12-17-2009 |
| 20090130760 | METHOD FOR THE UBIQUITINATION OF COMMON SUBUNIT OF RNA POLYMERASES - The present invention provides a method for ubiquitinating RNA polymerases, comprising bringing the RNA polymerases into contact with BRCA1-BARD1. | 05-21-2009 |
| 20090104280 | PHARMACEUTICAL COMPOSITIONS FOR TREATING/PREVENTING MOTOR ORGAN DISEASES - Fullerene inhibited the decrease in cell proliferation ability of chondrocytes which is observed when cultured chondrocytes are treated with a cartilage degenerating factor (IL-1β or H | 04-23-2009 |
