| SINGAPORE HEALTH SERVICES PTE LTD Patent applications |
| Patent application number | Title | Published |
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| 20120107413 | PRE-NATAL MESENCHYMAL STEM CELLS - We describe an pre-natal mesenchymal stem cell obtainable from a pre-natal tissue such as a foetal tissue, a descendent of such a mesenchymal stem cell, a cell culture or a cell line comprising either. The pre-natal mesenchymal stem cell, cell culture or cell line may comprise a cell line F1Ib, F2lb, F3lb, F1ki or F3li. We further describe a conditioned medium conditioned by such a pre-natal mesenchymal stem cell, cell culture or cell line. These may comprise cardioprotective activity, and may in particular be used to treat or prevent a range of cardiac disorders of diseases. | 05-03-2012 |
| 20110224565 | METHOD OF PREDICTING ACUTE CARDIOPULMONARY EVENTS AND SURVIVABILITY OF A PATIENT - According to embodiments of the invention, there is provided a method of producing an artificial neural network capable of predicting the survivability of a patient, the method including: storing in an electronic database patient health data, the patient health data comprising a plurality of sets of data, each set having at least one of a first parameter relating to heart rate variability data and a second parameter relating to vital sign data, each set further having a third parameter relating to patient survivability; providing a network of nodes interconnected to form an artificial neural network, the nodes comprising a plurality of artificial neurons, each artificial neuron having at least one input with an associated weight; and training the artificial neural network using the patient health data such that the associated weight of the at least one input of each artificial neuron of the plurality of artificial neurons is adjusted in response to respective first, second and third parameters of different sets of data from the patient health data, such that the artificial neural network is trained to produce a prediction on the survivability of a patient. | 09-15-2011 |
| 20110192726 | DEVICE AND METHOD FOR DETECTION OF ANALYTE FROM A SAMPLE - There is presently provided a device for detecting an analyte particle in a sample. The device comprises a chamber having an interior surface upon which is located an electrode array. The electrode array comprises pairs of electrodes, each pair having an inner electrode and an outer electrode that substantially surrounds the inner electrode. Each pair of electrodes is coated with a capture molecule that recognises and binds the analyte particle that is to be identified and quantified. The device uses a combination of dielectrophoresis and impedance measurements to capture and measure analyte particles from a sample. | 08-11-2011 |
| 20110144592 | Haemostatic Valve - A haemostatic valve according to an embodiment comprises a valve housing receiving an intravascular device, a first slider arranged on the valve housing moveable in a first direction, and a second slider received in the valve housing moveable in a second direction and elastically biased, the first slider being operatively connected to the second slider via a transmission mechanism so that movement of the first slider towards along the first direction causes the second slider to move away from an elastic valve member along the second direction, and the elastic valve member arranged between and compressible by the second slider, the elastic valve member receiving the intravascular device and compressing the intravascular device when being compressed by the second slider. | 06-16-2011 |
| 20110136935 | BONE AND/OR DENTAL CEMENT COMPOSITION AND USES THEREOF - The present invention provides a composition comprising: at least one viscosity-enhancing agent; and at least one macromonomer. In particular, the composition may be a bone cement composition and/or a dental cement composition. The composition may be used in medicine. The composition may be used in orthopedic and/or periodontal applications. The present invention also provides uses of the composition. | 06-09-2011 |
| 20110039760 | MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES - The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3. | 02-17-2011 |
| 20100048469 | ANTIMICROBIAL PEPTIDES - There is provided at least one isolated antimicrobial peptide, wherein the peptide is a linear analog of hBD3 or a fragment thereof. In particular, there is provided a linear analog of hBD3 wherein the peptide has a reduced cytotoxicity to at least one cell compared to the wild type hBD3. | 02-25-2010 |
| 20090258828 | INVESTIGATION OF MUCOSA DRYNESS CONDITIONS - The present invention relates to diagnosis and/or treatment of medical conditions. The present invention relates to new method of diagnosing dry mucosa condition in a subject. The condition may be dry eye. The present invention also provides a method to monitor the efficacy of a treatment of a dry mucosa condition, a method of treating a dry mucosa condition and/or a diagnostic kit for a dry mucosa condition. | 10-15-2009 |
