SILENSEED LTD. Patent applications |
Patent application number | Title | Published |
20150238517 | METHODS AND COMPOSITIONS FOR TREATING CANCER - Treatment of cancer by regional and prolonged release of one or more nucleotide-based agents is provided. | 08-27-2015 |
20150196648 | Methods and Compositions for Treating Prostate Cancer - Treatment of prostate cancer by regional and prolonged release of one or more nucleotide-based RNAi agents is provided. | 07-16-2015 |
20150050341 | METHODS AND COMPOSITIONS FOR RNAI-BASED CANCER TREATMENT - The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers. | 02-19-2015 |
20140314854 | METHODS AND COMPOSITIONS FOR RNAi-BASED CANCER TREATMENT - The present invention generally concerns methods and nucleotide-based compositions for treating metastatic cancer that is associated with a primary tumor or a few tumors at the primary organ. | 10-23-2014 |
20130280329 | METHODS AND COMPOSITIONS FOR RNAI-BASED CANCER TREATMENT - The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers. | 10-24-2013 |
20130142875 | METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER - Treatment of prostate cancer by regional and prolonged release of one or more nucleotide-based RNAi agents is provided. | 06-06-2013 |
20130122096 | COMPOSITIONS FOR DRUG DELIVERY AND METHODS OF MANUFACTURING AND USING SAME - Polymeric implants containing microparticles and nanoparticles, delivery of microparticles and nanoparticles from a polymeric implant is provided. | 05-16-2013 |
20110275891 | METHOD AND SYSTEM FOR IMPLANT DELIVERY - The present invention relates to a system and method for the delivery of a treatment element, and in particular, to such a system and method in which an implantable treatment element is implanted at a target site. | 11-10-2011 |
20110195123 | METHODS, COMPOSITIONS AND SYSTEMS FOR LOCAL DELIVERY OF DRUGS - Implantable medical device eluting drug locally and in prolonged period is provided, including several types of such a device, the treatment modes of implementation and methods of implantation. The device comprising of polymeric substrate, such as a matrix for example, that is used as the device body, and drugs, and in some cases additional scaffolding materials, such as metals or additional polymers, and materials to enhance visibility and imaging. The selection of drug is based on the advantageous of releasing drug locally and in prolonged period, where drug is released directly to the extracellular matrix (ECM) of the diseased area such as tumor, inflammation, degeneration or for symptomatic objectives, or to injured smooth muscle cells, or for prevention. One kind of drug is the gene silencing drugs based on RNA interference (RNAi), including but not limited to si RNA, sh RNA, or antisense RNA/DNA, ribozyme and nucleoside analogs. The modes of implantation in some embodiments are existing implantation procedures that are developed and used today for other treatments, including brachytherapy and needle biopsy. In such cases the dimensions of the new implant described in this invention are similar to the original implant. Typically a few devices are implanted during the same treatment procedure. | 08-11-2011 |