| Showa University Patent applications |
| Patent application number | Title | Published |
|---|
| 20110263017 | TECHNIQUE FOR REGULATING REGENRATION OF TISSUE OR FAULTY OR ABNORMAL PART IN ORGAN USING NELL-1 - The object aims to form and maintain a cell, a tissue or an organ induced by differentiation. Disclosed is a composition for inducing the differentiation of a cell capable of being differentiated in a given direction to thereby produce a cell, a tissue or an organ through the further induction of the differentiation in the given direction. The composition comprises NELL-1 or a substance which can be altered so as to act as NELL-1 upon the differentiation. Also disclosed is a composition for maintaining a cell, a tissue or an organ produced by the induction of the differentiation. | 10-27-2011 |
| 20110230447 | OSTEOGENESIS PROMOTER COMPRISING [4-(METHYLTHIO)PHENYLTHIO]METHANEBISPHOSPHONIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT - Disclosed are: a compound which can be produced through a chemical synthesis at low cost, has an excellent osteogenesis-promoting activity, has high affinity for a bone, and can be applied without the need of any special DDS; and a method for promoting osteogenesis by administering the compound and applying the promotion of osteogenesis to the formation or regeneration of a bone. Specifically disclosed are: an osteogenesis promoter or a pharmaceutical composition comprising [4-(methylthio)phenylthio]methanebisphosphonic acid, which is one of bisphosphonic acids, or a pharmaceutically acceptable salt thereof as an active ingredient; and a method for promoting osteogenesis, which comprises administering the osteogenesis promoter or the pharmaceutical composition to a subject to be treated. | 09-22-2011 |
| 20110165173 | THERAPEUTIC AGENT AND DETECTION REAGENT FOR ARTERIOSCLEROTIC DISEASE WHICH TARGETS FOR SALUSIN - The present invention provides a prophylactic and therapeutic agent for arteriosclerotic diseases and a method or reagent for detecting arteriosclerotic diseases. Further, the present invention provides a therapeutic agent for an arteriosclerotic disease, comprising salusin-α as an active ingredient, a therapeutic agent for an arteriosclerotic disease, comprising an antagonist of salusin-β as an active ingredient, and a method for detecting an arteriosclerotic disease, comprising assaying salusin-α in a biological sample. | 07-07-2011 |
| 20080262315 | Inspection method with endoscope - An endoscopic inspection method includes staining step and super magnified observation step. In the staining step, a distal end surface of a distal end portion of an endoscope which includes a distal end opening of a channel and a first lens that forms a super high-power observation optical system is held in contact with the tissue surface of the observation subject region such that the staining fluid supplied via the channel penetrates to the gap between the distal end surface and the tissue surface to eliminate the mucus on the tissue surface. The tissue surface having the mucus eliminated is stained with the staining fluid. In the super magnified observation step, the first lens which forms the super high-power observation optical system provided at the distal end portion is brought into contact with the tissue surface that has been stained with the staining fluid such that the observation at the cellular level is performed. | 10-23-2008 |
