| SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120095237 | Process for the Preparation of 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylates - The present invention discloses a process for obtaining 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate (formula I) by the reaction of 4,4-dimethyl-2-propyl-4,6-dihydrofuro[3,4-d]imidazole (formula II), or its hydrolysis product, or its ring-opening product, with alcohol under appropriate catalytic conditions. Furthermore, the present invention also provides a process for obtaining high purity 4,4-dimethyl-2-propyl-4,6-dihydrofuro[3,4-d]imidazole (formula II), therefore purified compound of formula I can be produced. Producing of olmesartan medoxomil at high purity is assured by said processes. R in formula I is selected from C | 04-19-2012 |
| 20120095035 | CRYSTALS OF PRASUGREL HYDROBROMATE - The present application discloses crystals of 2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrobromate, crystal compositions and pharmaceutical compositions comprising them and their use. The crystals of prasugrel hydrobromate of the present application possess excellent stability and solubility. | 04-19-2012 |
| 20110224414 | USE OF 9, 10-ANTHRAQUINONE COMPOUNDS - Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y | 09-15-2011 |
| 20110183996 | THE 1-BUTYL-2-HYDROXYARALKYL PIPERAZINE DERIVATIVES AND THE USES AS ANTI-DEPRESSION MEDICINE THEREOF - The invention discloses 1-butyl-2-hydroxyl aralkyl piperazine derivatives and their use as antidepressants. The derivatives of the present invention have triple inhibition effect on the reuptake of 5-HT, NA and DA, and can be administrated to the patients in need thereof in form of composition by route of oral administration, injection and the like. Compared with clinically currently used dual targets antidepressants (such as venlafaxine), said derivatives may have stronger antidepression effect, broader indications, faster onset and lower neurotoxicity and side reaction; and said derivatives have stronger antidepression activity, lower toxicity, higher bioavailability, longer half life and better druggablity, compared with aryl alkanol piperazine derivatives and optical isomers thereof disclosed in prior art. The 1-butyl-2-hydroxyl aralkyl piperazine derivative is the free alkali or its salt of a compound of formula below: | 07-28-2011 |
| 20110160247 | Aralkyl alcohol piperidine derivative and the use thereof as a medicament for treating depression - The present invention relates to an aralkyl alcohol piperidine derivative and use as antidepressant thereo. The said aralkyl alcohol piperidine derivative has a triple inhibition effect on the reuptaking of 5-HT, NA and DA. The derivative may be administered to the patient in need of such treatment in the form of composition by oral administration, injection and the like. The derivative is a compound having the following general formula or its salt: | 06-30-2011 |
| 20110160199 | Aralkyl Substituted Piperidine or Piperazine Derivatives and Their Use for Treating Schizophrenia - The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula. | 06-30-2011 |
| 20110152323 | Histone deacetylase inhibitors and uses thereof - The present invention discloses a group of histone deacetylase inhibitors and use thereof. The histone deacetylase inhibitors are useful in the treatment of malignant tumors and the diseases associated with differentiation and proliferation. The histone deacetylase inhibitors are the compounds represented by the following formula or salts thereof: | 06-23-2011 |
| 20110105503 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT - The present invention relates to aralkyl piperidine derivatives, compositions containing the same, and their uses in the preparation of antalgic or ataractic medicament. The said derivatives are a free base of the compound represented by the following formula or a salt thereof. The pharmacological experiments show that they display favorable antalgic, ataractic activity and low side effects. | 05-05-2011 |
| 20110046379 | Quinoline Compounds, Intermediates, Preparation Methods and Uses Thereof - A kind of quinoline compounds as formula A, pharmaceutical accepted solvates, optical isomers or polymorphisms thereof. The intermediates of formula D. in which, R | 02-24-2011 |
| 20100292141 | INSULIN NASAL POWDER INHALATION - An inhalable nasal powder preparation of insulin and its preparing process are provided. The powder inhalation is consisting of self-emulsifying freeze-dried powder and pharmaceutically acceptable carriers. The dry powder comprises insulin, fat(s), emulsifier(s), antioxidant(s), supporting agent(s), bio-gel adhesive(s), and pH modifier(s), wherein the emulsifier is a mixture of lecithin and Tween 80, and the amount of fat in the formulation is determined by the surface area and the particle diameter of oil droplet. | 11-18-2010 |
| 20100210856 | DITHIOLOPYRROLONE COMPOUNDS, THE PREPARATION AND THE USE THEREOF - The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X | 08-19-2010 |
