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Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, CN

Shanghai 9th People's Hospital, Shanghai Jiaotong University School of Medicine Patent applications
Patent application numberTitlePublished
20100197020TISSUE ENGINEERING TENDON AND CONSTRUCTION METHODS IN VITRO THEREOF - The invention discloses a tissue engineering graft, comprising:(a) pharmaceutically-acceptable biodegradable material; and (b) seed cells, which can be inoculated on the described biodegradable material and are selected from:(i) fibroblasts; (ii) adipose derived cells, or (iii) mixture of dermal fibroblasts and ASCs according to the ratio of 1:10000-10000:1. The graft can be prepared by mixing of seed cell and pharmaceutically-acceptable biodegradable material, obtaining a construct of seed cells and pharmaceutically-acceptable biodegradable material, then culturing the construct in a bioreactor in vitro. The graft can be used for repairing the defect of tendon tissues.08-05-2010