| SERUM INSTITUTE OF INDIA LTD. Patent applications |
| Patent application number | Title | Published |
|---|
| 20110263834 | Simple Method for Simultaneous Removal of Multiple Impurities from Culture Supernatants to Ultralow Levels - This invention is directed to methods for removing, preferably simultaneously and in one step, multiple impurities form crude culture samples, and, in particular, the removal of media components, protein, nucleic acids, lipids, and lipopolysaccharides to ultralow levels. Preferably the purification process comprises: (1) binding of the target substance containing one or more contaminants to a chromatography matrix; (2) washing the bound target substance with one or more buffers containing a synergistic combination of a lyotropic agent or organic solvent, a detergent, and a salt component; and (3) desorbing the target substance from the chromatography matrix, so that the eluate contains ultra low levels of contaminants. The reduction of impurities that can be achieved is preferably 91-99.9% as compared to the amount of impurities in the target substance before purification. The invention is also directed to the targets products that have been so purified. | 10-27-2011 |
| 20110177119 | STABLE, DRIED ROTAVIRUS VACCINE, COMPOSITIONS AND PROCESS FOR PREPARATION THEREOF - The present invention provides novel lyophilized rotavirus vaccine formulations and methods of their preparation. The formulations include vaccine stabilizers, resulting in a vaccine formulation with enhanced stability and minimal loss of potency. The rotavirus vaccine formulations comprise an advantageous ratio of a disaccharide (such as sucrose) to an amino acid (such as glycine). The lyophilization results in a virus formulation with 100% virus preservation and residual moisture from about 0.8% to 1.4%. | 07-21-2011 |
| 20100285064 | ADJUVANT COMPOSITION FOR VACCINE - The present invention provides a | 11-11-2010 |
| 20100129881 | Antigenic Polysaccharides and Process For Their Preparation - A robust and industrial scale process to afford highly pure antigenic polysaccharides is claimed. | 05-27-2010 |
| 20100086974 | HIGHLY PURE POLYSIALIC ACID AND PROCESS FOR PREPERATION THEREOF - The instant invention provides highly pure Polysialic acid and process for preparation thereof. | 04-08-2010 |
