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SECRETARY OF THE OFFICE OF THE COMMAND JUDGE ADVOCATE, HQ USAMRMC

Frederick, MD US

SECRETARY OF THE OFFICE OF THE COMMAND JUDGE ADVOCATE, HQ USAMRMC Patent applications
Patent application numberTitlePublished
20090081244Dry Formulation for Transcutaneous Immunization - A transcutaneous immunization system delivers antigen to immune cells through the skin, and induces an immune response in an animal or human. For example, skin-active adjuvant (e.g., an ADP-ribosylating exotoxin) can be used to induce an antigen-specific immune response (e.g., humoral and/or cellular effectors) after transcutaneous application of a dry formulation containing antigen and adjuvant to skin of the animal or human. The dry formulation may be a powder or a unit-dose patch. Use of adjuvant is not required if the antigen is sufficiently antigenic. Transcutaneous immunization may be induced with or without penetration enhancement03-26-2009