| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY Patent applications |
| Patent application number | Title | Published |
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| 20120020931 | THERAPEUTIC ENCAPSULATED EMBRYONIC STEM CELLS AND MESENCHYMAL STROMAL CELLS - This application discloses alginate microencapsulation-mediated differentiation of embryonic stem cells and use of the stem cell differentiation method for the development of effective treatment of various diseases and disorders. The microencapsulation of embryonic stem (ES) cells results in decreased cell aggregation and enhanced neural lineage differentiation through incorporating the soluble inducer retinoic acid (RA) into the permeable microcapsule system. This application also discloses a micro-encapsulation system for immobilizing mesenchymal stromal cells (MSCs) while sustaining the molecular communication. Thus, the invention provides the use of encapsulated mesenchymal stromal cells in the cellular transplantation therapies. Moreover, the invention provides methods for delivery of encapsulated MSCs into the central nervous system and therapies derived therefrom, such as, the treatment of spinal cord injury (SCI) and other inflammatory conditions. | 01-26-2012 |
| 20120004716 | MICROELECTORODE ARRAY, METHODS FOR PREPARING THE SAME AND USES THEREOF - A microelectrode array having a substrate with a plurality of grooves and a plurality of electrical contact pads, the grooves each with at least one electrode electrically connected to at least one of the electrical contact pads, each of the grooves containing at least one myotube that overlays the at least one electrode. | 01-05-2012 |
| 20120004235 | METHODS TO TREAT CANCER - The invention provides methods and pharmaceutical compositions for treating certain cancers with compounds of formula (I) wherein A, B, W, Y, Z, and R | 01-05-2012 |
| 20110320816 | SYSTEMS AND METHOD FOR MALWARE DETECTION - A system and method for distinguishing human input events from malware-generated events includes one or more central processing units (CPUs), one or more input devices and memory. The memory includes program code that when executed by the CPU causes the CPU to obtain a first set of input events from a user utilizing the input device. The first input events are used to obtain or derive a feature indicative of the user, such as a multi-dimensional feature vector as provided by a support vector machine. Second input events are then obtained, and the second input events are classified against the feature to determine if either the user or malware initiated the second input events. | 12-29-2011 |
| 20110318403 | Preparation and Use of Pouteria Lucuma Extract - A method of preparing | 12-29-2011 |
| 20110294917 | USE OF RECYCLED PLASTICS FOR STRUCTURAL BUILDING FORMS - Modular plastic structural composites formed from a mixture of (A) high density polyolefin and one or both of: (B) a thermoplastic-coated fiber material, or (C) polystyrene, poly(methyl methacrylate), or a combination thereof. Composites molded in the form of I-Beams and bridges constructed therefrom are also disclosed. | 12-01-2011 |
| 20110286926 | DEGRADABLE HYDROGEL COMPOSITIONS AND METHODS - This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for the timed cleavage of a particular amide bond in a covalently linked active agent or of the hydrogel structure. | 11-24-2011 |
| 20110282067 | ZEOLITIC IMIDAZOLATE FRAMEWORKS FOR KINETIC SEPARATION OF PROPANE AND PROPENE - Zeolitic Imidazolate Frameworks (ZIFs) characterized by organic ligands consisting of imidazole ligands that are either essentially all 2-chloroimidazole ligands or essentially all 2-bromoimidazole ligands are disclosed. Methods for separating propane and propene with the ZIFs of the present invention, as well as other ZIFs, are also disclosed. | 11-17-2011 |
| 20110275782 | BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES - New bioresorbable polymers are synthesized from monomer analogs of natural metabolites In particular, polymers are polymerized from analogs of amino acids that contribute advantageous synthesis, processing and material properties to the polymers prepared therefrom, including particularly advantageous degradation profiles | 11-10-2011 |
| 20110269848 | N-SUBSTITUTED MONOMERS AND POLYMERS - Biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an amide group, wherein said amide groups are N-substituted and the N-substituent and degree of N-substitution are effective to lower the melt viscosity, the solution viscosity, or both, compared to the same polymer without N-substitution. | 11-03-2011 |
| 20110268803 | LUNG TARGETING DUAL DRUG DELIVERY SYSTEM - The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments for NSCLC include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National Cancer Institute assesses, however, that results of standard treatment are generally poor with only a 15 percent 5-year survival rate for combined cancer stages. Challenges facing the current chemotherapy drugs include excessive toxicity to healthy tissues and limited ability to prevent metastases. A dual drug delivery system described herein selectively targets the lung to deliver anti-cancer drugs and inhibit the formation of metastases. | 11-03-2011 |
| 20110265410 | USE OF RECYCLED PLASTICS FOR STRUCTURAL BUILDING FORMS - Modular plastic structural composites having a web section disposed along a horizontal axis and at least one flange section disposed along a horizontal axis parallel thereto and integrally molded to engage the top or bottom surface of the web section, wherein said composite is formed from a mixture of (A) high density polyolefin and (B) a thermoplastic-coated fiber material, poly-styrene, or a combination thereof. Composites molded in the form of I-Beams and bridges constructed therefrom are also disclosed. | 11-03-2011 |
| 20110243417 | SYSTEM AND METHOD FOR ACCURATE AND RAPID IDENTIFICATION OF DISEASED REGIONS ON BIOLOGICAL IMAGES WITH APPLICATIONS TO DISEASE DIAGNOSIS AND PROGNOSIS - The present invention relates to a method and system for detecting biologically relevant structures in a hierarchical fashion, beginning at a low-resolution and proceeding to higher levels of resolution. The present invention also provides probabilistic pairwise Markov models (PPMMs) to classify these relevant structures. The invention is directed to a novel classification approach which weighs the importance of these structures. The present invention also provides a fast, efficient computer-aided detection/diagnosis (CAD) system capable of rapidly processing medical images (i.e. high throughput). The computer-aided detection/diagnosis (CAD) system of the present invention allows for rapid analysis of medical images the improving the ability to effectively detect, diagnose, and treat certain diseases. | 10-06-2011 |
| 20110201125 | METHODS AND RELATED DEVICES FOR CONTINUOUS SENSING UTILIZING MAGNETIC BEADS - A fluidic device including a main channel, wherein a first inlet fluidly connects to an upstream end of the main channel and introduces magnetic beads into a first side of the main channel A second inlet is fluidly connected to the upstream end of the main channel and introduces a sample stream into a second side of the main channel A first magnet disposed adjacent to the second side of the main channel pulls the magnetic beads towards a sidewall of the second side, and thus into the sample stream A second magnet disposed downstream from the first magnet and adjacent to a first side of the main channel subsequently pulls the magnetic beads towards a sidewall of the first side, and thus out of the sample stream A detection region is disposed at or downstream from the second magnet and in the first side of the main channel | 08-18-2011 |
| 20110201040 | NON-MCCJ25-RELATED LARIAT-PEPTIDE INHIBITORS OF BACTERIAL RNA POLYMERASE - The invention provides a method of inhibiting a bacterial RNA polymerases. The invention has applications in control of bacterial RNA polymerase activity, control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy. | 08-18-2011 |
| 20110200769 | COMPOSITIONS AND METHODS FOR THE PROTECTION OF SUBSTRATES FROM HEAT FLUX AND FIRE - A flame or heat flux protective coating composition, which includes a dispersion of fiberglass, hollow glass spheres, or a combination of both in silicone. A flame or heat flux protective sheet, which includes hollow glass spheres dispersed in silicone in a sheet form or fiberglass and silicone in a sheet form, wherein the fiberglass is dispersed in the silicone or the fiberglass is a woven cloth coated with the silicone is also presented. Articles incorporating the flame or heat flux protective coating or sheet form and methods for coating an article with the flame or heat flux protective coating composition are also presented. | 08-18-2011 |
| 20110188395 | Single Sensor Radio Scene Analysis for Packet Based Radio Signals using 2nd and 4th Order Statistics - We consider a problem of radio frequency (RF) signal analysis where one sensing node observes a frequency band possibly used by multiple packet based radio transmitters. Analysis of the received signal includes two steps. In the first step we use a spectrogram to perform temporal segmentation of the received nonstationary signal. This task may be formulated as a clustering problem. In the second step we compute a certain 2-D slice of the fourth order spectrum for each of the segments found in the first step. These fourth order spectrum slices are arraigned in a three-way array. One aspect of the second step is to use uniqueness properties of the low rank decomposition of the three-way array to recover spectra and associated activity sequences of individual components in the received signal. We derive a numerical algorithm for the low rank decomposition, which computes estimates of the spectra and activity sequences by optimizing certain weighted least squares criterion under application specific constraints. Certain embodiments are illustrated with simulation examples involving signals used in 802.11a/b/g and Bluetooth networks. The disclosed methods and related systems can be used as spectrum analysis tools, providing crucial information needed for achieving efficient utilization of radio spectrum and elimination of mutual interference between the coexisting systems. | 08-04-2011 |
| 20110182799 | SEQUESTRATION OF A GAS EMITTED BY AN INDUSTRIAL PLANT - A method of sequestering a multi-element gas emitted by an industrial plant is described herein, the method comprising: contacting a solution, including a first reactant comprising a multi-element gas emitted by an industrial plant and at least one gas absorber comprising nitrogen, for example ammonia or an amine, with a solid, including a second reactant, under conditions that promote a reaction between the first reactant and the second reactant to provide a first product, which incorporates one or more elements of the multi-element gas, thereby sequestering the multi-element gas. | 07-28-2011 |
| 20110179525 | COMPOSITIONS AND METHODS FOR BIOFUEL CROPS - Using the natural variation of sweet and grain sorghum to uncover genes that are conserved in rice, sorghum, and sugarcane, but differently expressed in sweet versus grain sorghum by using a microarray platform and the syntenous alignment of rice and sorghum genomic regions containing these genes. Indeed, enzymes involved in carbohydrate accumulation and those that reduce lignocellulose can be identified. Interestingly, C4 photosynthesis is enhanced as well. Furthermore, genetic analysis has shown that a specific microRNA is linked to flowering time and high sugar content in stems. | 07-21-2011 |
| 20110177964 | CHEMOSENSORY ARRAYS - A chemosensor array, a method of detecting ligands in a chemical mixture and a chemosensor system are provided. Chemosensor array designs are also provided. | 07-21-2011 |
| 20110158873 | SEQUESTRATION OF A GAS EMITTED BY AN INDUSTRIAL PLANT - A method of sequestering a multi-element gas emitted by an industrial plant is described herein, the method comprising: contacting a solution, including a first reactant comprising a multi-element gas emitted by an industrial plant and at least one gas absorber comprising nitrogen, for example ammonia or an amine, with a solid, including a second reactant, under conditions that promote a reaction between the first reactant and the second reactant to provide a first product, which incorporates one or more elements of the multi-element gas, thereby sequestering the multi-element gas. | 06-30-2011 |
| 20110143058 | METHODS OF INCREASING TOUGHNESS OF IMMISCIBLE POLYMER BLENDS - An immiscible polymer blend that includes an amount of poly(trimethylene terephthalate) (PTT) and an amount of poly(methylmethacrylate) (PMMA). A method for preparing an immiscible polymer blend by (a) identifying a first polymeric component and a second polymeric component as immiscible when blended; (b) combining the first polymeric component and the second polymeric component; and (c) mixing the first polymeric component and the second polymeric component to produce an immiscible polymer blend that includes structures in the blend having a maximum size of less than about 1,000 μm is also presented. An article that includes an immiscible polymer blend of poly(trimethylene terephthalate) (PTT) and poly(methylmethacrylate) (PMMA) and an article formed from an immiscible polymer blend prepared by the method of the present invention are also presented. | 06-16-2011 |
| 20110136812 | SOLUBILIZED TOPOISOMERASE POISONS - The invention provides compounds of formula I: | 06-09-2011 |
| 20110136260 | SNAPIN AND METHODS FOR REGULATION OF MICROTUBULE ASSEMBLY AND DENDRITE GROWTH AND BRANCHING - Fragments of snapin important for interaction with cypin and thus regulating microtubule assembly are provided. Also provided are methods of use of said fragments and kits to facilitate said methods. | 06-09-2011 |
| 20110136169 | EXPRESSION SYSTEM COMPOSITIONS AND METHODS - The present invention relates to novel expression systems and methods for preparing samples for 3D structure determination of a protein based on a protein expression vector, | 06-09-2011 |
| 20110135732 | MULTIPLE PHASE CROSS-LINKED COMPOSITIONS AND USES THEREOF - The present invention is directed to pharmaceutical compositions, and method for preparing pharmaceutical compositions, comprising a cross-linked matrix physically entrapping at least one therapeutic agent. The matrix may comprise one or more phases in addition to an aqueous phase, such as a solid and/or oil phase. The matrix of the invention has at least one controlled release in-vivo kinetic profile, and may have additional profiles for the same agent. The matrix may also comprise more than one therapeutic agent, and each additional therapeutic agent may have one or more controlled release in-vivo kinetic profile. | 06-09-2011 |
| 20110129851 | Methods for Obtaining Bioactive Compounds from Phytoplankton - Phytoplankton represent a potential source of bioactive compounds. The present disclosure provides, inter alia, methods for identifying glycerolipids and apoptosis-inducing sphingosine-like lipids from virally-infected phytoplankton. | 06-02-2011 |
| 20110120447 | Tilting/Tracking System for Solar Devices - A tracking system is provided for a roof-mounted solar array. The system includes a sensor mechanism for sensing an orientation of the sun relative to the solar array, and a controller connected to the sensor mechanism that generates a signal that represents an optimal tilt angle of the solar array relative to the orientation of the sun. An actuator connected to the controller receives the signal from the controller and adjusts the tilt angle of the solar array in response to the received signal. | 05-26-2011 |
| 20110117024 | NANOCARRIER AND NANOGEL COMPOSITIONS - Novel classes of multi-arm polyalkylene oxide-based materials including PEG nanocarriers, nanogel particles, and aggregated nanogel particles are disclosed. These classes of compositions may be associated with therapeutic agents and targeting moieties, or visibility enhancing agents, and may have a modified surface structure. In some embodiments the PEG-based materials can be made to provide relatively high drug loads with improved solubility and targeted delivery. | 05-19-2011 |
| 20110091652 | FLAME-RETARDANT COATING - A flame-retardant coating composition, which includes a cross-linked thermosetting polymer and a metal hydroxide. A precursor composition for use in preparing the flame retardant-coating is also presented, wherein the precursor composition includes a cross-linked thermosetting polymer varnish, a metal hydroxide, an alcohol, and water. A method for coating an article with a flame-retardant coating layer and articles incorporating the flame-retardant coating are also presented. | 04-21-2011 |
| 20110081296 | SYSTEMS AND METHODS FOR IDENTIFICATION OF CILIOPATHY THERAPEUTICS - The invention provides systems and methods for identifying therapeutic targets for treating a disease including a ciliopathy. The invention further provides for drug discovery, and animal model systems related to drug discovery. The invention further relates to therapy of genetic disorders of the cellular cilia or basal bodies. | 04-07-2011 |
| 20110064846 | METHODS FOR REDUCING REACTIVE CARBONYL SPECIES - Methods for reducing the concentration of reactive carbonyl species, for example, in thermally processed foods, including beverages, are provided herein. | 03-17-2011 |
| 20110056372 | ELECTROSTATIC SCREEN DEVICE AND METHOD FOR EMISSION CONTROL - An electrostatic screen battery for emission control (ESBEC) system includes a plurality of screens. The screens are arranged in an alternating manner so that screens at a first electric potential are interposed with screens at a second electric potential. An ionizer is disposed upstream of the screens. An exhaust stream passes by the ionizer and then through the screens, where particulates are deposited onto the screens. In preferred embodiments the screens have hydrophobic surfaces. | 03-10-2011 |
| 20110033503 | DRESSING COMPOSITIONS AND METHODS - Described is a spray-on hydrogel comprising water-soluble PEG polymers that cross-link in situ to form a hydrogel such that the cross-links are reversible. The hydrogel can be useful as a drug delivery composition, wound dressing or surgery adjuvant. Polyethylene glycol polymer and cross-linker solutions are sprayed simultaneously through a common orifice. Cross-linking via formation of thioether or disulfide bonds is initiated upon mixing, providing rapid gelation. The hydrogel components can be derivatized with RGD peptides or analogs thereof to promote retention in/on a body compartment such as the skin, surface of the eye, or a mucosa such as the vaginal mucosa. The cross-links are reversed using a reducing solution enabling easy removal of the hydrogel by dissolution. Processes for preparation of the cross-linker, RGD derivatized PEG and RGD-linked agents are also disclosed. | 02-10-2011 |
| 20110022161 | IODINATED POLYMERS - The invention provides medical devices that comprise an iodinated polymer and that can be viewed using X-Ray imaging techniques. The invention also provides novel iodinated polymers that can be incorporated into or coated on medical devices. | 01-27-2011 |
| 20100329529 | COMPUTER ASSISTED DIAGNOSIS (CAD) OF CANCER USING MULTI-FUNCTIONAL, MULTI-MODAL IN-VIVO MAGNETIC RESONANCE SPECTROSCOPY (MRS) AND IMAGING (MRI) - This invention relates to computer-assisted diagnostics and classification of prostate cancer. Specifically, the invention relates to segmentation of the prostate boundary on MRI images, cancer detection using multimodal multi-protocol MR data; and their integration for a computer-aided diagnosis and classification system for prostate cancer. | 12-30-2010 |
| 20100320074 | METHOD FOR PREPARING GALLIUM NITRIDE NANOPARTICLES - A method for preparing gallium nitride nanoparticles includes providing a pair of electrodes; the pair of electrodes being opposedly disposed to one another. One electrode of the pair of electrodes is filled with gallium nitride powder. The pair of electrodes is dipped in a liquid. An arc discharge is produced between the pair of electrodes. The arc discharge produces a plasma between the pair of electrodes. | 12-23-2010 |
| 20100311074 | SWITCH-REGION: TARGET AND METHOD FOR INHIBITION OF BACTERIAL RNA POLYMERASE - The invention provides a target and methods for specific binding and inhibition of RNA polymerase from bacterial species. The invention provides methods for identifying agents that bind to a bacterial RNA polymerase, and that inhibit an activity of a bacterial RNA polymerase, through interactions with a bacterial RNA polymerase homologous switch-region amino-acid sequence. Said methods comprise preparing a reaction solution comprising the compound to be tested and an entity containing a bacterial RNAP homologous switch-region amino-acid sequence, and detecting binding or inhibition. The invention has applications in control of bacterial gene expression, control of bacterial viability, control of bacterial growth, antibacterial chemistry, and antibacterial therapy. | 12-09-2010 |
| 20100291181 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH - The invention provides therapeutic devices comprising a polymeric anti-inflammatory agent that biodegrades to release anti-inflammatory agents. The therapeutic devices are useful for repair and regeneration of a variety of injured tissues. | 11-18-2010 |
| 20100282631 | METHOD OF RECYCLING PAINTS AS A COMPONENT OF AN IMMISCIBLE POLYMER BLEND - An immiscible polymer blend including a first polymer component including a paint polymer phase and a second polymer component immiscible with the first polymer component and selected from polyolefins and polymethylmethacrylate (PMMA). A method of recycling paint by blending a first polymer component including a paint polymer phase with a second polymer component immiscible with the first polymer component and selected from polyolefins and polymethylmethacrylate (PMMA) is also presented. | 11-11-2010 |
| 20100266164 | METHOD AND APPARATUS FOR MAKING AND DETECTING A DOCUMENT VERIFICATION INDICATOR USING OPTICAL PATTERN ENCRYPTION - A method and apparatus for creating and detecting an optically encoded document having a uniquely designed document verification indicator is disclosed. One embodiment includes applying a spatially varying Brewster angle pattern on a substrate. Another embodiment includes an apparatus for detecting the spatially varying Brewster angle pattern including a light source, a slit aperture, a polarizer, at least one parabolic mirror, and an image capturing device. | 10-21-2010 |
| 20100261171 | NUCLEIC ACID SEQUENCES FOR BIOSYNTHESIS OF NON-MCCJ25-RELATED LARIAT PEPTIDES - A nucleic acid sequence is provided, encoding at least one of a precursor of a lariat peptide, a processing factor of a lariat peptide, and an export factor of a lariat peptide, wherein the lariat peptide is a non-MccJ25 lariat peptide according to general structural formula (I) Also provided are biosynthesis systems useful for the synthesis of peptides according to formula (I), and methods of detecting and identifying nucleic acid sequences encoding the disclosed proteins. | 10-14-2010 |
| 20100240664 | SOLUBILIZED TOPOISOMERASE POISON AGENTS - The invention provides compounds of formula I: | 09-23-2010 |
| 20100233730 | THERAPEUTIC MODULATION OF AUTOPHAGY - Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed. | 09-16-2010 |
| 20100228009 | Labeled Biomolecular Compositions and Methods for the Production and Uses Thereof - Disclosed herein is a set of | 09-09-2010 |
| 20100221246 | METHODS AND COMPOSITIONS FOR TREATING CANCER - The present invention provides methods of treating cancer using 2-amino-6-trifluoromethoxybenzothiazole (riluzole). In one aspect, the present invention provides methods of reducing cancer cell growth. In another aspect, the present invention provides a method of inducing apoptosis in a cancer cell. In another aspect, the present invention provides a method of reducing the growth of a glutamate-releasing tumor. | 09-02-2010 |
| 20100215719 | POLYARYLATES FOR DRUG DELIVERY AND TISSUE ENGINEERING - Biocompatible polyarylates of diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed. | 08-26-2010 |
| 20100169024 | DEFINING QUANTITATIVE SIGNATURES FOR DIFFERENT GLEASON GRADES OF PROSTATE CANCER USING MAGNETIC RESONANCE SPECTROSCOPY - A method for classifying a possible cancer from a magnetic resonance spectrographic (MRS) dataset includes extracting at least one feature from the MRS dataset as being identified with the possible cancer and embedding the extracted feature into a low dimensional space to form an embedded space. The method then clusters the embedded space into clusters representing a plurality of predetermined classes and spectrally decomposing the clusters to identify substantially significant independent metabolic signatures. The method then classifies the possible cancer as belong to one of at least two cancer classes based on the identified independent metabolic signatures. | 07-01-2010 |
| 20100166854 | ELECTROSPUN MATRICES FOR DELIVERY OF HYDROPHILIC AND LIPOPHILIC COMPOUNDS - A method of forming electrospun fiber mats from a plurality of different biodegradable polymeric fibers is provided, in which a plurality of up to six different biodegradable polymer solutions are electrospun together by a method comprising the steps of providing a plurality of up to six different biodegradable polymer solutions each containing at least one biologically or pharmaceutically active material and each in communication with a needle for electrospinning a biodegradable polymer fiber from the solution, and pumping each solution through its respective needle into an electric field under conditions effective to produce uncontrolled charged jet streams of the polymer solutions directed at a grounded rotating mandrel, thereby forming fiber threads of the biologically or pharmaceutically active compounds and polymers in the solutions that are deposited on the mandrel to form an electrospun non-woven fiber mat, wherein the needles are positioned for co-deposition of the fiber threads from the polymer solution streams together on the mandrel to form a fiber mat. | 07-01-2010 |
| 20100152410 | HIGH MOLECULAR WEIGHT POLYMERS, DEVICES AND METHOD FOR MAKING AND USING SAME - Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices. | 06-17-2010 |
| 20100149983 | BROADCAST LATENCY OPTIMIZATION IN MULTIHOP WIRELESS NETWORKS - A system and methodology that can optimize practical performance by reducing broadcast latency and collisions in a multihop wireless network is provided. The system includes an optimization component that determines a schedule for transmitting and/or receiving messages at nodes in the network during one-to-all broadcasting, all-to-all broadcasting, and/or all-to-one collection. The schedule enables each node in wireless network to participate in broadcasting as soon as possible, such that, when a node transmits a message to its parent to deliver the message to a source node, the children of the node also receive the message and initiate broadcasting the message in their subtrees in parallel. Further, during data collection, the schedule for messages to be transmitted to a sink node is determined based in part on a priority associated with the message. Additionally, the generated schedule does not affect a set of theoretical bounds associated with a broadcast algorithm employed by the network. | 06-17-2010 |
| 20100148224 | POWER JUNCTION FIELD EFFECT POWER TRANSISTOR WITH HIGHLY VERTICAL CHANNEL AND UNIFORM CHANNEL OPENING - A semiconductor vertical junction field effect power transistor formed by a semiconductor structure having top and bottom surfaces and including a plurality of semiconductor layers with predetermined doping concentrations and thicknesses and comprising at least a bottom layer as drain layer, a middle layer as blocking and channel layer, a top layer as source layer. A plurality of laterally spaced U-shaped trenches with highly vertical side walls defines a plurality of laterally spaced mesas. The mesas are surrounded on the four sides by U-shaped semiconductor regions having conductivity type opposite to that of the mesas forming U-shaped pn junctions and defining a plurality of laterally spaced long and vertical channels with a highly uniform channel opening dimension. A source contact is formed on the top source layer and a drain contact is formed on the bottom drain layer. A gate contact is formed on the bottom of the U-shaped trenches for the purpose of creating and interrupting the vertical channels so as to turn on and turn off the transistor. | 06-17-2010 |
| 20100136091 | METHODS, SYSTEMS, AND COMPOSITIONS FOR EXTRACELLULAR MATRIX PRODUCTION - Compositions, methods, and kits for repair and production of extracellular matrix are provided. In the broad aspect, the composition comprises a ligand of α5β1 integrin attached to a surface of a nanoparticle composed of a protein, with a proviso that the protein is not fibronectin. | 06-03-2010 |
| 20100102825 | Spectral and information theoretic method of test point, partial-scan, and full-scan flip-flop insertion to improve integrated circuit testability - Design for testability (DFT) algorithms, which use both gradient descent and linear programming (LP) algorithms to insert test points (TPs) and/or scanned flip-flops (SFFs) into large circuits to make them testable are described. Scanning of either all flip-flops or a subset of flip-flops is supported. The algorithms measure testability using probabilities computed from logic simulation, Shannon's entropy measure (from information theory), and spectral analysis of the circuit in the frequency domain. The DFT hardware inserter methods uses toggling rates of the flip-flops (analyzed using digital signal processing (DSP) methods) and Shannon entropy measures of flip-flops to select flip-flops for scan. The optimal insertion of the DFT hardware reduces the amount of DFT hardware, since the gradient descent and linear program optimizations trade off inserting a TP versus inserting an SFF. The linear programs find the optimal solution to the optimization, and the entropy measures are used to maximize information flow through the circuit-under-test (CUT). The methods limit the amount of additional circuit hardware for test points and scan flip-flops. | 04-29-2010 |
| 20100081126 | PROCESS FOR DESIGNING INHIBITORS OF INFLUENZA VIRUS STRUCTURAL PROTEIN-1 - Disclosed are methods and compositions useful in identifying inhibitors of influenza virus, such as influenza A and B virus. Also disclosed are methods for preparing compositions for administration to animals, including humans infected with or to protect against influenza virus. | 04-01-2010 |
| 20100075927 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE - Chemotherapeutic conjugates of a peptide substrate to a phosphoramide chemotherapeutic agent in which a peptide substrate is covalently linked to the chemotherapeutic agent by a linker with an aminoarylmethyl or aminoheteroaryl moiety, wherein the linking of the peptide to the chemotherapeutic agent inhibits the cytotoxic activity of the chemotherapeutic agent, the peptide is a substrate for proteolytic cleavage by a tumor-specific enzyme; and the linker is capable of undergoing 1,6-elimination in vivo upon cleavage of the peptide substrate. Methods for synthesizing and methods of using the conjugates are also disclosed. | 03-25-2010 |
| 20100063242 | PREPARATION AND USES OF POLYARYLATES - The present invention is directed to polyarylates comprising repeating units having the structure: | 03-11-2010 |
| 20100047780 | TARGET AND METHOD FOR INHIBITION OF BACTERIAL RNA POLYMERASE - Target and method for inhibition of bacterial RNA polymerase disclosed are targets and methods for specific binding and inhibition of RNAP from bacterial species. | 02-25-2010 |
| 20100040668 | Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof - The present invention is related to methods for preparing composite materials, which include nanoscale hydroxyapatite, and the composite materials and articles prepared therewith. | 02-18-2010 |
| 20100031387 | PREVENTION OF TRANSGENE ESCAPE IN GENETICALLY MODIFIED PERENNIALS - Genes can be introduced into plants that confer desirable traits such as, drought and stress tolerance, insect and pest resistance, as well as environmental qualities such as phyto-remediation. However, possibility for transgene escape to wild and non-transformed species raises commercial and ecological concerns. Disclosed herein are methods and compositions for generating sterile perennial plants for the prevention of transgene escape. For example, sterile switchgrass can be produced using these methods, for example which can be used to produce biofuel. | 02-04-2010 |
| 20090324757 | Compositions and Methods for Modulating Visceral Sensation and/or Gastrointestinal Reflex Activity - The invention relates to compositions capable of modulating visceral sensation and/or gastrointestinal activity obtained from botanical sources. More specifically, the invention relates to compositions comprising an extract product of an | 12-31-2009 |
| 20090317472 | CONTROLLED RELEASES OF ACTIVES IN SKIN - Topical compositions are provided in which active compounds for topical delivery through the stratum corneum are complexed with nanospheres of a triblock copolymer having an A-B-A structure wherein each A end block is a water-soluble, hydrophilic and non-toxic polymer or oligomer; and the hydrophobic middle B block is a hydrophobic polymer or oligomer with the same or different repeating units having the structure according to formula:(I) wherein X is —C —R—C— or —C—; Z is between 2 and about 100, inclusive; R | 12-24-2009 |
| 20090293633 | Uniform Shear Application System and Methods Relating Thereto - Disclosed herein is a shear application system for applying substantially uniform amounts of shear throughout a powder sample. The shear application system preferably includes a cylinder assembly having an inner cylinder, a housing, an inner set of lugs, and an outer set of lugs. The inner cylinder has an external cylindrical surface and the housing has an internal cylindrical surface concentric with said external cylindrical surface. The internal and external cylindrical surfaces form an annular chamber therebetween. Each one of the lugs of the inner set extend radially outward from the external cylindrical surface, and each one of the lugs of the outer set extend radially inward from the internal cylindrical surface and are substantially uniformly spaced. The shear application system preferably includes drive means mechanically connected to the inner cylinder and control means electrically connected to the drive means. | 12-03-2009 |
| 20090287623 | METHOD AND APPARATUS FOR USING BAYESIAN NETWORKS FOR LOCALIZATION - The invention is a technique for performing sampling in connection with Markov Chain Monte Carlo simulations in which no attempt is made to limit the selected samples to a selected slice of the entire sample domain, as is typical in Markov Chain Monte Carlo sampling. Rather, samples are taken from the entire domain and any samples that fall below a randomly selected probability density level are discarded. | 11-19-2009 |
| 20090285895 | Pharmaceutical Formulation for Regulating the Timed Release of Biologically Active Compounds Based on a Polymer Matrix - A formulation containing a biologically active compound having a structure with hydrogen bonding sites is blended with a polymer having a structure with complementary hydrogen bonding sites, the polymer forming hydrolytic degradation products that promote the release of the biologically active compound from the polymer. | 11-19-2009 |
| 20090258890 | TOPOISOMERASE-TARGETING AGENTS - The invention provides compounds of formula I or formula II: | 10-15-2009 |
| 20090242655 | RAILROAD TIE THAT OBVIATES THE NEED FOR A TIE PLATE - A plastic or polymer composite railroad tie, which includes at least one rail seat bordered on at least one side by a raised portion of the tie. | 10-01-2009 |
| 20090239871 | SOLUBILIZED TOPOISOMERASE POISONS - The invention provides compounds of formula I: | 09-24-2009 |
| 20090238858 | Compositions and Methods for Treating Ophthalmic Diseases - Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with biocompatible diphenol com-pound monomer units with pendant carboxylic acid ester groups and poly(alkylene oxide) blocks, wherein the molar fraction in the copolymer of biocompatible diphenol compound monomer units with pendant carboxylic acid groups and poly(alkylene oxide) blocks relative to the weight percentage of the drug in the composition is effective to provide pseudo-zero order release of the drug from the composition during the sustained-release phase of drug delivery under physiological conditions. Ocular treatment methods and manufacturing methods are also disclosed. | 09-24-2009 |
| 20090221203 | COMPOSITIONS AND METHODS FOR THE PROTECTION OF SUBSTRATES FROM HEAT FLUX AND FIRE - A flame or heat flux protective coating composition, which includes a dispersion of fiberglass, hollow glass spheres, or a combination of both in silicone. A flame or heat flux protective sheet, which includes hollow glass spheres dispersed in silicone in a sheet form or fiberglass and silicone in a sheet form, wherein the fiberglass is dispersed in the silicone or the fiberglass is a woven cloth coated with the silicone is also presented. Articles incorporating the flame or heat flux protective coating or sheet form and methods for coating an article with the flame or heat flux protective coating composition are also presented. | 09-03-2009 |
| 20090175932 | MICELLE ASSEMBLIES - The invention encompasses micelle assemblies, compositions having micelle assemblies, and methods for preparing micelle assemblies and compositions thereof. Also, the invention encompasses compounds of the formula: A-X-Y-Z-R | 07-09-2009 |
| 20090104254 | Controlled Release Hydrogels - Formulations and methods for their preparation including a hydrogel including a crosslinked matrix comprising a polymer, and a one or more liposomes containing a therapeutic agent. | 04-23-2009 |
| 20090042716 | High Temperature Reactor for the Poduction of Nanophase WC/CO Powder - A method for producing a nanostructured cermet material, including the steps of preparing an aqueous solution mixture of precursor compounds of the cermet material, introducing the solution mixture into a heated tubular reactor in the form of a fine-particle aerosol, and processing the solution mixture in the heated tubular reactor to form the nanostructured cermet material. The present invention is further directed to a processing apparatus configured for implementing the present method. | 02-12-2009 |
| 20090035248 | Fast Degrading Polymers - The invention provides polyanhydrides that degrade in less than 60 hours following topical administration to deliver biologically active compounds. | 02-05-2009 |
| 20090029358 | Methods and Compositions for the Diagnosis and Treatment of Schizophrenia - Compositions and methods relating to the diagnosis and treatment of neuropsychiatric disorders, such as schizophrenia, schizoaffective disorders, and bipolar disorders are disclosed. Also provided are methods for screening therapeutic agents having efficacy for the treatment of such disorders. | 01-29-2009 |
| 20080311411 | LOW-TEMPERATURE CURE INORGANIC COMPOSITIONS - A protective inorganic composition that includes: (a) a liquid composition portion that includes by weight percent of the liquid composition portion: from about 54% to about 58% by weight water, from about 22% to about 26% by weight of an alkali metal oxide component that includes potassium oxide, wherein up to about 30% by weight of the alkali metal oxide component includes sodium oxide, and from about 18% to about 22% by weight amorphous silica; and (b) a powder composition portion that includes by weight percent of the powder composition portion: up to about 65% by weight amorphous silica and one or more components selected from calcined clay, a Group II metal oxide powder, high-temperature resistant fillers, microfibers, and discrete fibers. Also provided are methods for coating a substrate and articles prepared therefrom. | 12-18-2008 |
| 20080289418 | ANGULAR VELOCITY SENSOR - An angular velocity sensor includes a protrusion protruding in a Y′-axis direction and extending in an X-axis direction on a main surface of a rotated Y cut quartz plate, and an excitation electrode and a detection electrode formed on the main surface adjacent to this protrusion. This excitation electrode excites thickness-shear vibration in the X-axis direction on the quartz substrate, exiting vibration on the protrusion. Then, the protrusion is bent and displaced due to Coriolis force acting in a direction orthogonal to the vibration of the protrusion corresponding to a rotation around an Y′ axis. This displacement at the protrusion is applied to the quartz substrate as stress. The detection electrode detects change of this stress, thereby angular speed added to the angular velocity sensor is detected. | 11-27-2008 |
| 20080280813 | COMPLEX DRUG DELIVERY COMPOSITION AND METHOD FOR TREATING CANCER - The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses. | 11-13-2008 |
| 20080274158 | Hydrazide Compounds with Angiogenic Activity - Compounds exhibiting angiogenic properties incorporating the structure of Formula I: | 11-06-2008 |
| 20080246003 | Thermodynamically Stable Solutions Of Chalcogenide-Bound Lanthanide Compounds With Improved Quantum Efficiency - Thermodynamically stable solutions of chalcogenide-bound Ln compounds with one or more Ln ions coordinated or bound by chalcogenolate, chalcogenide or polychalcogenido ligands by means of the ligand chalcogenide atom, wherein the Ln compounds are dissolved at a level up to about 90 vol. % in a host solvent optically transparent to wavelengths at which excitation, fluorescence or luminescence of the Ln ions occurs. | 10-09-2008 |
| 20080213232 | Radial Glial Cells Promote Nerve Regeneration and Functional Recovery Following Spinal Cord Injury - An enriched population of radial glial cells has been isolated. These cells are nestin | 09-04-2008 |
