| Ruprecht-Karls-Universitat-Heidelberg Patent applications |
| Patent application number | Title | Published |
|---|
| 20110262081 | OPTICAL CONNECTORS AND A METHOD OF PRODUCTION THEREOF - The invention relates to a method for producing an active optical connection with an optoelectronic element and a light deflection means for light deflection between the optoelectronic element and an optical waveguide arranged transversely with respect to the beam direction of said element. In this case, it is provided that a carrier substrate for the optoelectronic element is arranged in a highly precisely repeatably positioning machine, in particular a flip-chip machine, the optoelectronic element is mounted on the substrate by a or the highly precisely repeatably positioning machine and a curable, moldable compound is applied over the optoelectronic element, and the moldable compound is molded by a mold for molding light deflection means, said mold being moved by a or the highly precisely repeatably positioning machine, and at the earliest thereafter the substrate is removed from the or a highly precisely repeatably positioning machine. | 10-27-2011 |
| 20100087630 | Use of XCR1 for Diagnosing or Monitoring of Immune Tolerance - The invention relates to measuring immunological tolerance in T cells. In particular, the invention provides a method for measuring the tolerance status of a T cell sample, comprising the steps of (a) measuring the expression level of XCR1 (also known as GPR5, which is a receptor for Single C Motif-1/Lymphotactin) in a T cell sample, and (b) comparing the measured expression level with a reference value, said reference value being representative of the expression level of XCR1 in a control T cell sample. The present invention furthermore provides methods, kits and uses to determine the required stringency of immunosuppression, particularly the required dosage of an immunosuppressant. Also provided are methods and uses to identify or validate inducers or inhibitors of immunological tolerance. | 04-08-2010 |
| 20100068825 | Method and Device for Detecting at Least One Property of at Least One Object with a Microchip - The present invention relates to a method and a device for the detection of at least one property of at least one object. The detection is effected by means of a microchip. The microchip has at least one readable detection pixel. In order to reduce the technical equipment outlay during object detection, the method according to the invention is characterized by the fact that the at least one object is arranged at the microchip in a spatially predetermineable position. The at least one object is exposed to illumination light in order to detect the illumination light that interacts with the at least one object or the light that is induced by the illumination light and emerges from the at least one object by means of the at least one readable detection pixel of the microchip. | 03-18-2010 |
| 20090263002 | Wave field microscope with sub-wavelength resolution and methods for processing microscopic images to detect objects with sub-wavelength dimensions - The invention relates to a computer implemented method for processing of microscopic images to detect objects of interest. The method includes subjecting the microscopic image to a bandpass filtering to obtain a filtered image, wherein the bandpass filtering is such as to suppress the noise and any objects which are larger than a predetermined size; and processing the filtered image at a plurality of progressively decreasing threshold levels. The processing at each threshold level includes detecting the objects of interest using an object labelling algorithm and removing the detected objects detected at a given threshold level from the working image before proceeding to the next threshold level. | 10-22-2009 |
| 20090082258 | Means and Methods for Treating Advanced Stage Neuroblastoma - The present invention relates to uses of compounds having a structure as shown by formula (I) for the manufacture of a pharmaceutical composition for the treatment of neuroblastoma. Moreover, the present invention encompasses methods of treatment for said diseases. | 03-26-2009 |
| 20090048121 | Screening Method for the Early Diagnosis of Cerebral Vasospasm - The invention relates to screening methods and test systems for the in vitro diagnosis and detection of an increased risk of vasospasm in a patient. In addition, the invention describes the use of GAPDH and/or Hsc70 to diagnose an increased risk of vasospasm. Also described is a method for identifying a pharmaceutically active substance for the prevention and/or treatment of cerebral vasospasm and a method for screening a substance library to identify a pharmaceutically active substance for the prevention and/or treatment of cerebral vasospasm. Pharmaceutically active substances and combination preparations are also disclosed. | 02-19-2009 |
