| ROBARTS RESEARCH INSTITUTE Patent applications |
| Patent application number | Title | Published |
|---|
| 20110195050 | USE OF A COMBINATION OF MYXOMA VIRUS AND RAPAMYCIN FOR THERAPEUTIC TREATMENT - The present invention relates to therapeutic use of a combination of Myxoma virus, including in combination with rapamycin. Treatment with rapamycin enhances the ability of Myxoma virus to selectively infect cells that have a deficient innate anti-viral response, including cells that are not responsive to interferon. The combination of rapamycin and Myxoma virus can be used to treat diseases characterized by the presence of such cells, including cancer. The invention also relates to therapeutic use of Myxoma virus that does not express functional M135R. | 08-11-2011 |
| 20110163751 | TRANSCEIVE SURFACE COIL ARRAY FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY - A surface coil array comprises a surface coil support and an arrangement of non-overlapping magnetically decoupled surface coils mounted on the support. The surface coils encompass a volume into which a target to be imaged is placed. Magnetic decoupling circuits act between adjacent surface coils. Impedance matching circuitry couples the surface coils to conventional transmit and receive components. | 07-07-2011 |
| 20110158945 | MYXOMA VIRUS MUTANTS FOR CANCER TREATMENT - Myxoma viruses that are deficient in the activity of a Myxoma virus protein selected from the group consisting of M11L, M063, M 136, M-T4 and M-T7 are useful for treating cancer. | 06-30-2011 |
| 20110091448 | METHODS FOR REGULATION OF STEM CELLS - Methods are provided for increasing stem cells, hematopoietic progenitor/stem cells, mesenchymal progenitor/stem cells, mesodermal progenitor/stem cells, muscle progenitor/stem cells, or neural progenitor/stem cells in vivo in a mammalian subject. Methods are also provided for treating an immune related disease, a mesenchymal/mesoderm degenerative disease, or a neurodegenerative disease in a mammalian subject in need thereof. | 04-21-2011 |
| 20090198094 | APPARATUS AND COMPUTING DEVICE FOR PERFORMING BRACHYTHERAPY AND METHODS OF IMAGING USING THE SAME - An apparatus for determining a distribution of a selected therapy in a target volume is provided. A three-dimensional ultrasound transducer captures volume data from the target volume. A computing device is in communication with the three-dimensional ultrasound transducer for receiving the volume data and determining the distribution of the selected therapy in the target volume along a set of planned needle trajectories using the volume data. At least one of the needle trajectories is oblique to at least one other of the planned needle trajectories. | 08-06-2009 |
| 20090079432 | TRANSCEIVE SURFACE COIL ARRAY FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY - A surface coil array comprises a surface coil support and an arrangement of non-overlapping magnetically decoupled surface coils mounted on the support. The surface coils encompass a volume into which a target to be imaged is placed. Magnetic decoupling circuits act between adjacent surface coils. Impedance matching circuitry couples the surface coils to conventional transmit and receive components. | 03-26-2009 |
| 20090035276 | USE OF A COMBINATION OF MYXOMA VIRUS AND RAPAMYCIN FOR THERAPEUTIC TREATMENT - The present invention relates to therapeutic use of a combination of Myxoma virus, including in combination with rapamycin. Treatment with rapamycin enhances the ability of Myxoma virus to selectively infect cells that have a deficient innate anti-viral response, including cells that are not responsive to interferon. The combination of rapamycin and Myxoma virus can be used to treat diseases characterized by the presence of such cells, including cancer. The invention also relates to therapeutic use of Myxoma virus that does not express functional M135R. | 02-05-2009 |
