| RIKEN Patent applications |
| Patent application number | Title | Published |
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| 20120136135 | THERMOSTABLE BIOPOLYESTER - A biopolyester which is poly(3-hydroxyalkanoate) or poly(3-hydroxyalkanoate) copolymer and has a reduced calcium content. It has improved thermal stability due to the reduced calcium content. | 05-31-2012 |
| 20120135934 | COMBINED PREPARATION FOR TREATING JOINT DISEASES - An object of the present invention is to enable the repair and regeneration of articular cartilage, which could not be achieved by conventional therapies, and to provide a safe and inexpensive agent that is effective for the treatment of joint diseases such as osteoarthritis. According to the present invention, a combined formulation for simultaneously, separately, or sequentially administering a hyaluronic acid and an animal mucin-type glycoprotein for the treatment of joint diseases is provided. | 05-31-2012 |
| 20120121535 | AGENT FOR PREVENTING RECURRENCE OF LEUKEMIA - The present invention provides a drug capable of initiating the progression of the cell cycle of leukemia stem cells to overcome the resistance of the leukemia stem cells to cell cycle-dependent chemotherapeutic agents, and a drug for suppressing recurrence of leukemia containing the same, and the like, an agent containing G-CSF, wherein the agent is for inducing the progression of the cell cycle of leukemia stem cells, a drug for suppressing recurrence of leukemia containing a combination of G-CSF and a cell cycle-dependent antitumor agent, and the like. | 05-17-2012 |
| 20120110699 | METHOD FOR PROMOTING THE FORMATION OF SECONDARY CELL WALL OF PLANT - Provided is a method for increasing the thickness of the secondary cell wall of a plant. A method for increasing the thickness of the secondary cell wall of a plant by using a tracheary element differentiation (TED)-associated protein or a C-terminal fragment of the same, which comprises constructing a transgenic (Tg) plant containing, in an expressible manner, a DNA encoding protein(s) selected from the group consisting of a combination of TED6 with TED7, a C-terminal fragment of TED6, a C-terminal fragment of TED7, and a combination of a C-terminal fragment of TED6 with a C-terminal fragment of TED7, and expressing said DNA in said plant; the Tg plant; and a progeny, a cell, a tissue or a seed of the same. | 05-03-2012 |
| 20120101266 | 18F-LABELED AZIDE COMPOUND, REAGENT FOR 18F-LABELING AND METHOD FOR 18F-LABELING OF ALKYNE COMPOUND USING SAME | 04-26-2012 |
| 20120070450 | LEUKEMIA STEM CELL MARKERS - The invention provides a test method for predicting the initial onset or a recurrence of acute myeloid leukemia (AML) comprising (1) measuring the expression level of human leukemic stem cell (LSC) marker genes in a biological sample collected from a subject for a transcription product or translation product of the gene as an analyte and (2) comparing the expression level with a reference value; an LSC-targeting therapeutic agent for AML capable of suppressing the expression of a gene selected from among LSC marker genes or a substance capable of suppressing the activity of a translation product of the gene; a method for producing a sample containing hematopoietic cells for autologous transplantation or allogeneic transplantation for AML patients comprising obtaining an LSC-purged sample with at least 1 kind of LSC marker as an index; and a method of preventing or treating AML. | 03-22-2012 |
| 20120067172 | METAL RECOVERY METHOD USING PROTONEMATA OF MOSS PLANTS - Disclosed is a method for recovery of a metal using plants. The method for recovery of a metal involves bringing a protonema of a moss plant belonging to the family Funariaceae into contact with a metal-containing solution in which a metal(s) having an ionization tendency lower than that of silver is dissolved. | 03-22-2012 |
| 20120066777 | TEST AGENT FOR VISCERAL OBESITY AND USE THEREOF - Disclosed are: a method for detecting (diagnosing) visceral obesity in a subject; a test agent useful for the method; a method for searching for a substance that can be used as an active ingredient for ameliorating visceral obesity; and an ameliorating agent for visceral obesity or a medicinal agent for preventing a metabolic disease developed as a result of the progression of visceral obesity. As the test agent, a polynucleotide which comprises at least 15 nucleotides and can hybridize with a nucleotide sequence for coiled-coil domain containing protein 3 (CCDC3) gene or a nucleotide sequence complementary to the nucleotide sequence under stringent conditions or an antibody capable of recognizing CCDC3 protein is used. | 03-15-2012 |
| 20120040464 | METHOD FOR GENERATING HOMOPLASMIC CELLS FROM HETEROPLASMIC CELLS - It is an object of the present invention to provide a method, which comprises allowing a eukaryotic cell to come into contact with a reactive oxygen species or a chemical species that generates such a reactive oxygen species in the cell, and thereby changing the percentage of mutant mtDNA (mitochondrial genomic DNA) in the cell, and cells obtained by the above-described method. | 02-16-2012 |
| 20120040376 | LUNG CANCER DIAGNOSTIC POLYPEPTIDE, METHOD FOR DETECTING LUNG CANCER, AND METHOD FOR EVALUATING THERAPEUTIC EFFECT - A novel biomarker for use in lung cancer diagnosis is provided. | 02-16-2012 |
| 20120034643 | FLUORESCENT PROTEIN - An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived from | 02-09-2012 |
| 20120034226 | DIAGNOSTIC METHOD OF SKIN INFLAMMATORY DISEASE - The invention provides a method of determining (or diagnosing) the presence or absence of a functional abnormality in the skin barrier, a kit therefor, a method of ameliorating a functional abnormality in the skin barrier based on the onset mechanism, and a drug therefor. The method of determining the presence or absence of a functional abnormality in the skin barrier comprises measuring the expression of a protease and/or an inhibitor thereof on the skin surface of a test object, and the like. | 02-09-2012 |
| 20120028330 | POLYPEPTIDE HAVING ACTIVITY OF AMINOACYL-tRNA SYNTHETASE AND USE THEREOF - A polypeptide according to the present invention includes: an altered polypeptide obtained by altering an ArgRS, a CysRS, a MetRS, a GlnRS, a GluRS, a LysRS, a TyrRS, or a TrpRS so that an unnatural amino acid is recognized; and an editing polypeptide derived from a PheRS, a LeuRS, an IleRS, a ValRS, an AlaRS, a ProRS, or a ThrRS, the editing polypeptide having been either inserted between a Rossman-fold N domain and a Rossman-fold C domain that exist in the altered polypeptide, or bound to an N terminal of the altered polypeptide. Thus provided are a new aaRS that exhibits high substrate specificity to an unnatural amino acid and a technique that involves the use of such an aaRS. | 02-02-2012 |
| 20120028313 | OLIGONUCLEOTIDE LINKERS COMPRISING A VARIABLE COHESIVE PORTION AND METHOD FOR THE PREPARATION OF POLYNUCLEOTIDE LIBRARIES BY USING SAID LINKERS - The present invention relates to a linker or population of linkers that include an oligonucleotide fixed portion and an oligonucleotide variable portion represented by formula (N)n, wherein N is A, C, G, T or U, or their derivatives, and n is an integer equal to or higher than 1. A linker-polynucleotide or a population of linker-polynucleotides of the invention may be constituted by said linker or population of linkers and a target first strand polynucleotide bound to said linker. The invention also encompasses a method of preparing said linker or population of linkers and a method of preparing a linker-polynucleotide using said linker or population of linkers. The linkers or polynucleotide-linkers of the invention can be used in a method of preparing a cDNA library. | 02-02-2012 |
| 20120025252 | COMPOSITE SUBSTRATE FOR FORMATION OF LIGHT-EMITTING DEVICE, LIGHT-EMITTING DIODE DEVICE AND MANUFACTURING METHOD THEREOF - A composite substrate for the formation of a light-emitting device, ensuring that a high-quality nitride-based light-emitting diode can be easily formed on its top surface and the obtained substrate-attached light-emitting diode functions as a light-emitting device capable of emitting light for an arbitrary color such as white, is provided. A composite substrate for the formation of a light-emitting device, comprising a light-converting material substrate for radiating at least a part of incident light as light different in the wavelength through the surface opposite the incident surface, and at least two or more Al-containing nitride layers formed on the light-converting material substrate, wherein the light-converting material substrate has a texture comprising two or more oxide phases continuously and three-dimensionally entangled with each other, including an Al | 02-02-2012 |
| 20120002850 | REGION DATA EDITING APPARATUS, REGION DATA EDITING METHOD, AND RECORDING MEDIUM - A region data editing apparatus includes a contour deforming section for receiving a contour deforming operation in which a contour of a region in a three-dimensional image is deformed, a boundary surface deforming section for deforming a boundary surface ∂D in such a manner that the boundary surface ∂D follows the contour deformed by the contour deforming operation, and a region data updating section for updating region data in such a manner that the region data thus updated represents an inside of the boundary surface which has been deformed by the boundary surface deforming section. | 01-05-2012 |
| 20120001910 | IMAGE DISPLAY APPARATUS, IMAGE DISPLAY METHOD, CURVED LINE SPECIFYING APPARATUS, CURVED LINE SPECIFYING METHOD, AND RECORDING MEDIUM - A curved line specifying apparatus includes a curved surface specifying section for receiving a curved surface specifying operation in which a curved surface S in a virtual three-dimensional space is specified and a cross section image display section for outputting, to a display, the curved surface in which a cross section image of a three-dimensional image is embedded, pixel values of the cross section image being voxel values assigned to voxels on the curved surface S. | 01-05-2012 |
| 20120001067 | DIFFERENTIAL MOBILITY ANALYZER, PARTICLE MEASURING SYSTEM, AND PARTICLE SORTING SYSTEM - In order to provide a differential mobility analyzer and the like that allows (i) easy increase of an upper limit of particle size of charged particle which can be classified and (ii) analysis of charged particles whose particle size is variable, a DMA (Differential Mobility Analyzer) includes: a classification tank in which an inlet electrode having an inlet slit, an intermediate electrode having a slit, and an outlet electrode having an outlet slit are arranged in sequence in such a manner that adjacent electrodes are disposed opposing each other at predetermined intervals; a gas supply section supplying the classification tank with sheath gas; and a voltage generator applying a predetermined voltage between the electrodes disposed opposing each other, the classification tank including a first classification section and a second classification section each formed by the electrodes disposed opposing each other, and the gas supply section controlling a flow rate of the sheath gas to be supplied to the classification tank individually per first classification section and second classification section. | 01-05-2012 |
| 20110307964 | MOUSE HAVING HUMAN LEUKEMIC STEM CELL AND LEUKEMIC NON-STEM CELL AMPLIFIED THEREIN, AND METHOD FOR PRODUCTION THEREOF - The invention relates to a method of selectively expanding human leukemic cells in a non-adult NOD/SCID/IL2rg | 12-15-2011 |
| 20110306653 | STABILIZATION METHOD OF FUNCTIONAL NUCLEIC ACID - This invention is intended to enhance and improve the resistance of a single- or double-stranded nucleic acid fragment comprising a base sequence of a functional nucleic acid to degradation by nucleolytic enzymes in a simple and cost-effective manner. The single- or double-stranded nucleic acid fragment comprises, ligated to at least one end thereof, hairpin-shaped DNA comprising: (A) a nucleic acid region comprising 2 to 5 arbitrary nucleotides; (B) a nucleic acid region comprising a “gna” or “gnna” base sequence, wherein each “n” represents “g”, “t”, “a”, or “c”, a base analogue, or a modified base; and (C) a nucleic acid region comprising a base sequence complementary to the nucleic acid region (A), sequentially from the 5′ end toward the 3′ end. | 12-15-2011 |
| 20110301043 | RISK ASSESSMENT FOR CUTANEOUS ADVERSE DRUG REACTIONS FROM ANTIRETROVIRAL AGENT - The present invention provides a method of predicting the risk of a patient for developing cutaneous adverse drug reaction to non-nucleoside reverse transcriptase inhibitors such as nevirapine by using HLA-B*3505 allele and/or polymorphisms in the CCHCR1 gene. | 12-08-2011 |
| 20110300575 | CELL-FREE SYSTEM FOR SYNTHESIS OF PROTEINS DERIVED FROM CULTURED MAMMALIAN CELLS - Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein synthesis system comprising an extract prepared from cultured mammalian cells and a template mRNA. These factors are one or more selected from the group consisting of eukaryotic translation initiation factors 4E (eIF4E), 2 (eIF2) and 2B (eIF2B), and eukaryotic translational regulator p97. | 12-08-2011 |
| 20110287036 | NOVEL CANCER TARGETING THERAPY USING COMPLEX OF SUBTANCE CAPABLE OF BINDING SPECIFICALLY TO CONSTITUENT FACTOR OF CANCER STROMA AND ANTI-TUMOR COMPOUND - The present invention is intended to provide a pharmaceutical for tumor treatment that stays specifically in interstitium for a long time and exhibits an effect, and provides a complex consisting of a substance having specific binding affinity for stroma and an antitumor compound bound to the substance via a linker. | 11-24-2011 |
| 20110282014 | NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF - The invention relates to a norbornene copolymer having excellent properties such as transparency, heat resistance, low water absorption and electric insulating property, which copolymer comprises a monomer unit represented by formula (1) and formula (2) | 11-17-2011 |
| 20110280895 | IMMUNOTHERAPEUTIC METHOD USING ALLO-CELLS WHICH CO-EXPRESS CD1d AND TARGET ANTIGEN - The present invention provides a means to be used for a new immunotherapy of cancer or infection utilizing activation of dendritic cell (DC) by innate immunity, namely, a method of preparing a cell co-expressing a target antigen and CD1d and having an ability to activate immunity against the target antigen, comprising the following steps (a) and (b): | 11-17-2011 |
| 20110280881 | NOVEL ANTI-HSP90 MONOCLONAL ANTIBODY - [Summary] The present invention relates an anti-HSP90 antibody and use thereof, more specifically to an anti-HSP90 antibody capable of recognizing cell surface HSP90, a vaccine that utilizes the antibody, a drug that utilizes the antibody, an adjuvant comprising the antibody, a method of detecting a cell expressing HSP90 on the cell surface using the antibody, and the like. | 11-17-2011 |
| 20110277189 | MUTANT PLANT, A METHOD FOR PRODUCING THEREOF AND A METHOD OF INCREASING FREQUENCY OF A GENETIC RECOMBINATION - According to the present invention, a technique of increasing the frequency of genetic recombination in genomic DNA of a plant is established. Such technique comprises: introducing a restriction enzyme gene that can be expressed in a target plant cell into the plant cell and causing the restriction enzyme gene to be transiently expressed so as to induce genetic recombination of genomic DNA; or introducing a promoter and a restriction enzyme gene using the | 11-10-2011 |
| 20110270566 | SCHEDULING DEVICE, SCHEDULING METHOD, SCHEDULING PROGRAM, STORAGE MEDIUM, AND MASS SPECTROMETRY SYSTEM - The present invention provides a scheduling device which can carry out scheduling of process execution periods of time, included in plural pieces of processing target data, respectively. The scheduling device sorts out plural pieces of substance data by looking up a retention time, included in each of the plural pieces of substance data. The scheduling device groups the plural pieces of substance data into a plurality of functions Fn so that pieces of substance data, included in each of the plurality of functions Fn, is successively arrayed in an order resulting from the sorting. Further, the scheduling device finds, for each of the plurality of functions Fn, a function range between a detection start time included in that function Fn and a detection end time included in that function Fn, and groups the plurality of functions Fn into a measurement group(s) In so that an interval between functions Fn included in the same measurement group is more than a condition set in advance. | 11-03-2011 |
| 20110269945 | FLUORESCENT PROTEIN - An object of the present invention is to provide a novel fluorescent protein derived from | 11-03-2011 |
| 20110265225 | TRANSGENIC PLANT HAVING INCREASED SEED SIZE - The present invention relates to a transgenic plant having increased seed size prepared via introduction of DNA encoding a protein consisting of a specific amino acid sequence derived from a plant, such as rice, and a method for producing the same. | 10-27-2011 |
| 20110263849 | METHOD FOR RAPIDLY METHYLATING HETEROAROMATIC ARENE AND METHOD FOR PRODUCING TRACER FOR USE IN PET - Provided is a method whereby a heteroaromatic ring aryl can be very rapidly methylated at a high yield. In an N-alkyl-2-pyrrolidinone, a heteroaromatic ring aryltrialkylstannan is cross-coupled with methyl iodide in the presence of a palladium complex, a phosphine ligand, a cuprous halide, a carbonic acid salt and/or an alkali metal fluoride to thereby rapidly methylate the heteroaromatic ring aryl. (Formula shows a case wherein the heteroaromatic ring aryl is a pyridyl group.) | 10-27-2011 |
| 20110263687 | RNA MOLECULES AND USES THEREOF - The present invention relates to substantially single-stranded isolated RNA molecules comprising 18 to 19 contiguous nucleotides that corresponds to a non-protein-coding genomic DNA sequence located between −60 and +120 nucleotides from a transcription start site in a mammalian genome. Specifically, the isolated RNA molecules have a high GC content (>60%), are nuclear specific, and may be associated with aberrant gene regulation and/or transcription in various mammalian diseases and conditions. The isolated RNA molecules, modified RNA molecules and fragments thereof may be particularly useful for the diagnosis, prognosis and treatment of diseases such as Crohn's disease, Alzheimer's disease, Parkinson's disease, rheumatoid arthritis, myocardial infarction, diabetes, congenital developmental disorders, coronary heart disease and cancer such as breast cancer, lymphoma, leukemia, aggressive metastatic brain cancers, colorectal cancer, gastric cancer, ovarian cancer and pituitary tumors. | 10-27-2011 |
| 20110258737 | RICE GENE CAPABLE OF IMPARTING WIDE-SPECTRUM DISEASE RESISTANCE - A three-step screening of selection for resistance against pathogenic bacteria infection, selection for resistance against pathogenic fungi infection, and selection for sensitivity to salicylic acid was carried out on | 10-20-2011 |
| 20110243910 | MAMMALIAN RNA DEPENDENT RNA POLYMERASE - The invention provides compositions comprising a TERT-RMRP or TERT-RNA complex and methods of treating subjects with genetic diseases in which gene silencing is either increased by administering the compositions of the invention or decreased by administering an inhibitor of the RNA-dependent RNA polymerase (RdRP) activity of these compositions. Moreover, the invention provides methods of screening for agonists and antagonists of RdRP activity and TERT-RMRP complex formation. Finally, the invention provides a method of identifying a RNA molecule that forms a complex with a TERT polypeptide and has RdRP activity. | 10-06-2011 |
| 20110241863 | DRIVER OPERATION PREDICTION DEVICE, METHOD, AND DRIVER OPERATION PREDICTION PROGRAM - A deviation angle, between a progression direction of a vehicle and a direction of a target destination point after a predetermined forward gaze duration on a target course the vehicle is travelling on, is detected by target destination point deviation angle detection unit. A yaw angular speed proportional to the deviation angle detected by the target destination point deviation angle detection unit is predicted by yaw angular speed prediction unit, as a yaw angular speed realized by steering wheel operation by a driver after a predetermined lag time for matching a timing of change in the vehicle movement with a timing of change in curvature of the target course. By so doing, the yaw angular speed due to steering wheel operation by a driver can be predicted with good precision. | 10-06-2011 |
| 20110237774 | METHOD FOR INTRODUCING DOTA - The invention provides a method for introducing 1,4,7,10-tetraazacyclododecane-N,N′,N″,N′″-tetraacetic acid (DOTA) into a compound such as a peptide. The method comprises a first step for preparing a mixed liquid of DOTA having no protecting group and dimethylsulfoxide, and a second step for contacting the mixed liquid with the compound carried on a solid-phase carrier. | 09-29-2011 |
| 20110236900 | NOVEL MUTS PROTEIN AND METHOD FOR DETERMING MUTATION USING THE SAME - A method for determining the presence or absence of a mutation on the basis of the presence or absence of amplification with high reliability is provided. A target sequence including a target site contained in a sample nucleic acid is amplified using a primer that can hybridize to a region including the target site contained in the sample nucleic acid in the presence of a novel MutS having an amino acid sequence of SEQ ID NO: 2, and then the presence or absence of a mutation at the target site is determined on the basis of the presence or absence of amplification. The novel MutS binds more specifically to a mismatched base pair than to a fully-matched base pair, whereby an extension reaction caused by a mismatch-binding primer is suppressed. Thus, according to the present invention, the presence or absence of a mutation can be determined with high reliability. | 09-29-2011 |
| 20110236362 | NKT CELL-DERIVED iPS CELLS AND NKT CELLS DERIVED THEREFROM - Provided are an iPS cell derived from a somatic cell such as an NKT cell, having the α-chain region of the T cell antigen receptor gene rearranged to uniform Vα-Jα in an NKT cell receptor-specific way, NKT cells differentiated from the iPS cell, a method of creating the same, and an immune cell therapy agent prepared using cells differentiated from the iPS cell. Also provided are an iPS cell having TCRα rearranged to NKT-TCR (NKT-iPS cell), obtained by contacting a somatic cell, such as an NKT cell, having the α-chain region of the T cell antigen receptor gene rearranged to uniform Vα-Jα in an NKT cell receptor-specific way, with nuclear reprogramming factors, isolated NKT cells obtained by differentiating the iPS cell ex vivo (iPS-NKT cell), a method of generating CD4/CD8-double positive NKT cells (DP-NKT cells) and mature NKT cells from NKT-iPS cells by altering the combination of feeder cells and/or cytokines, a method of expanding the iPS-NKT cells, and an NKT cell cytotherapy agent comprising NKT cells activated with α-galactosyl ceramide (α-GalCer), or iPS-NKT cells, and α-GalCer in combination. | 09-29-2011 |
| 20110231944 | B CELL-DERIVED IPS CELLS AND APPLICATION THEREOF - Provided are a B cell-derived iPS cell generated using a convenient technique, a technology for providing a human antibody at low cost using the iPS cell, an immunologically humanized mouse prepared using cells differentiated from the iPS cell, and the like. Also provided are a cloned cell obtained by contacting a B cell with nuclear reprogramming factors excluding C/EBPα and Pax5 expression inhibiting substances, particularly nucleic acids that encode Oct3/4, Sox2, Klf4 and c-Myc, wherein the cloned cell has an immunoglobulin gene rearranged therein and possesses pluripotency and replication competence (B-iPS cell). Still also provided are a method of producing a monoclonal antibody against a specified antigen, comprising recovering an antibody from a culture of B cells obtained by differentiating a B-iPS cell derived from a B cell immunized with the specified antigen, and a method of generating an immunologically humanized mouse, comprising transplanting to an immunodeficient mouse a human immunohematological system cell obtained by differentiating a B-iPS cell. | 09-22-2011 |
| 20110225674 | Transformed plants or algae with highly expressed chloroplast protein BPG2 - This invention provides a transformed plant or alga with increased chlorophyll, comprising an overexpressed foreign DNA which codes for a chloroplast protein BPG2 or a homologue thereof, and a method for producing the transformed plant or alga. | 09-15-2011 |
| 20110224158 | ESTERIFIED ALPHA-GALACTOSYLCERAMIDE - The invention provides esterified α-galactosylceramides effective for cancer treatment and the like, and a medicament containing same. In particular, the invention relates to a compound represented by the formula (I): | 09-15-2011 |
| 20110223636 | FLUORESCENT PROTEIN AND CHROMOPROTEIN - It is an object of the present invention to provide a novel fluorescent protein and a novel chromoprotein. The present invention provides a novel fluorescent protein derived from | 09-15-2011 |
| 20110216312 | SEMICONDUCTOR INSPECTION DEVICE AND INSPECTION METHOD - For a semiconductor device S, an inspection is performed in a zero-bias state by use of electromagnetic waves generated by irradiation of pulsed laser light, and an inspection range is set with reference to layout information of the semiconductor device S to perform two-dimensional scanning by inspection light L | 09-08-2011 |
| 20110206615 | PROBE REAGENT FOR MEASURING OXIDATIVE STRESS - The present invention relates to fluorescent or luminescent probe reagents for measuring oxidative stress in a cell or an organism. Examples of the probe reagents include: a fluorescent or luminescent protein and a marker protein; a fluorescent or luminescent protein, a marker protein, and a regulatory factor; or a fluorescent or luminescent protein, a marker protein, a cleavage sequence, and a regulatory factor. In the probe reagents, the marker protein makes it possible to detect the oxidative stress caused by reactive oxygen species and comprises a regulatory factor-binding site and a ubiquitin-binding site; and the regulatory factor is a protein making it possible to regulate degradation of the marker protein in response to the reactive oxygen species. The present invention also relates to a method of measuring oxidative stress in a cell or an organism, or a method of screening a substance which suppresses or promotes the oxidative stress in a cell or an organism by using the probe reagent. | 08-25-2011 |
| 20110201142 | Method of Manufacturing a Light-Emitting Device - To provide a light-emitting device using a nitride semiconductor which can attain high-power light emission by highly efficient light emission, a method of manufacturing the light-emitting device involves forming a first AlGaN layer of a first conductivity type on a side of a first main surface of a nitride semiconductor substrate, forming a light-emitting layer including an InAlGaN quaternary alloy on the first AlGaN layer, forming a second AlGaN layer of a second conductivity type on the light-emitting layer, and removing the nitride semiconductor substrate after forming the second AlGaN layer. | 08-18-2011 |
| 20110196415 | MATERIAL FOR ANEURYSM CURING - It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment. | 08-11-2011 |
| 20110179521 | PLANT SHOWING RESISTANCE TO MULTIPLE DISEASES AND METHOD FOR PRODUCING THE SAME - It is found that multiple different resistance genes adjacent to each other on the genome of | 07-21-2011 |
| 20110177084 | NOVEL USE APPLICATION OF SUGAR CHAIN-RECOGNIZING RECEPTOR - Provided are a novel means for regulating inflammatory reactions by regulating the signaling in inflammatory responses caused by non-homeostatic cell death, specifically an anti-inflammatory agent comprising a substance that inhibits the expression of Mincle or the interaction of Mincle and SAP130 or FcRγ, a screening method for a substance that regulates inflammatory reactions, comprising contacting Mincle or a fragment containing an extracellular region thereof and SAP130 in the presence and absence of a test substance, and comparing the degrees of the interaction of Mincle or the fragment thereof and SAP130 under the two conditions, a method of detecting non-homeostatic cell death, comprising measuring the amount of SAP130 in a sample collected from a subject animal, and the like. | 07-21-2011 |
| 20110171738 | METHOD FOR ESTIMATING THE AMOUNT OF IMMOBILIZED PROBES AND USE THEREOF - The present invention provides a method for estimating an amount of immobilized probes, including the successive steps of: providing a sample on a substrate to form one or more spots of the sample on the substrate, the sample containing particulate substances and probes in a predetermined ratio, the probes being reactive with a predetermined target; measuring the number of the particulate substances contained in at least one of the spots; and estimating the amount of the probes contained in the at least one of the spots from the thus measured number of the particulate substances. | 07-14-2011 |
| 20110161273 | RIBONUCLEIC ACID IDENTIFICATION APPARATUS, RIBONUCLEIC ACID IDENTIFICATION METHOD, PROGRAM AND RIBONUCLEIC ACID IDENTIFICATION SYSTEM - Disclosed are an apparatus for the identification of a ribonucleic acid, whereby not only the molecular weights of digestion products, from which nothing but the nucleic acid residue composition can be understood, but also nucleic acid residue sequence data is obtained from a product ion mass set and thus the identification reliability for the individual digestion products can be remarkably improved; a method for the identification of a ribonucleic acid; and a program and system for the identification of a ribonucleic acid. The method as described above comprises: searching for nucleic acid sequence database by using a fragment mass set indicating the molecular weights and inner structural data of individual oligonucleotides that are obtained by tandem mass spectrometry on digested oligonucleotides formed by chemically or enzymatically cleaving a ribonucleic acid; scoring candidate sequences; among candidate sequences showing the highest scores, referring those showing scores exceeding the threshold as identified sequences; and using these identified sequences in mapping on nucleic acid sequence database including genomic sequences. | 06-30-2011 |
| 20110159505 | Method of Manufacturing a Mixture of Amplified Double-Stranded Nucleic Acids Comprising Unknown Sequence - The purpose of the subject invention is to provide a method of manufacturing a mixture of amplified double-stranded nucleic acids comprising unknown sequence including the complete 5′ end sequence, | 06-30-2011 |
| 20110158955 | METHOD FOR PRODUCING CELLS HAVING CHARACTERISTIC OF HEMATOPOIETIC STEM CELLS/PROGENITOR CELLS - Provided are a new method of producing cells having characteristics of hematopoietic stem/progenitor cells, for use in hematopoietic stem cell transplantation, and hematopoietic stem/progenitor cell-like cells produced by the method. Provided in particular are a method of producing hematopoietic stem/progenitor cell-like cells retaining differentiation pluripotency and self-replication potential, comprising (1) a step for providing a mammalian pro-B cell or progenitor cell thereof, and (2) a step for culturing the cell (1) above under conditions for induction of differentiation into B cells, wherein the function and/or expression of the transcription factor E2A is suppressed at least at the stage of pre-pro-B cells or pro-B cells in the process (2) above; a hematopoietic stem/progenitor cell-like cell produced by the method; and an immunotherapeutic agent comprising the hematopoietic stem/progenitor cell-like cell, and the like. | 06-30-2011 |
| 20110152709 | MOBILE BODY CONTROL DEVICE AND MOBILE BODY CONTROL METHOD - A mobile body control device includes: a brain activity detecting unit that detects brain activity information of a user; a brain signal separating unit that separates an artifact component from the brain activity information detected by the brain activity detecting unit; a control signal generating unit that slides a sampling period for extracting brain data, at predetermined intervals in an overlapped manner in the brain activity information from which the artifact component is separated, successively calculates feature values for the brain data within each of the sampling periods obtained by sliding, and generates a control signal based on the feature values calculated; and a drive control unit that drives and controls a mobile body with a user riding thereon, based on the control signal generated. | 06-23-2011 |
| 20110152502 | FLUORESCENT PROTEIN - The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b); | 06-23-2011 |
| 20110150312 | BIODATA MODEL PREPARATION METHOD AND APPARATUS, DATA STRUCTURE OF BIODATA MODEL AND DATA STORAGE DEVICE OF BIODATA MODEL, AND LOAD DISPERSION METHOD AND APPARATUS OF 3D DATA MODEL - Medical image data is utilized, physical values are assigned to body parts based on image information, and the target organs are separated from the image data to prepare a 3D biodata model to thereby realize a data model unique to a patient, having an internal structure, and enabling dynamic simulation of a live body. The same target part of a body is captured by CT and MRI to obtain medical images. Sets of pairs of CT images and MRI images are set, a plurality of features showing the same locations are selected and set from the sets of CT images and MRI images, a conversion coefficient between the CT images and MRI images is obtained, and this conversion coefficient is used to rearrange the MRI images by projection transforms and linear interpolation, combine them with the contours of the CT images, and correct their positions in the contours. Further, the images are used to prepare a 3D data model. | 06-23-2011 |
| 20110136995 | AROMATIC VINYL COMPOUND-CONJUGATED DIENE COMPOUND COPOLYMER AND METHOD OF PRODUCING THE SAME AS WELL AS RUBBER COMPOSITION AND TIRE - This invention relates to an aromatic vinyl compound-conjugated diene compound copolymer capable of giving excellent wear resistance and resistance to wet skid to a tire, and more particularly to an aromatic vinyl compound-conjugated diene compound copolymer obtained by an addition polymerization of an aromatic vinyl compound and a conjugated diene compound in the presence of a polymerization catalyst composition comprising at least one specified metallocene complex selected from the group consisting of a metallocene complex represented by the following general formula (I): | 06-09-2011 |
| 20110136204 | EXTRACT OF E. COLI CELLS HAVING MUTATION IN RIBOSOMAL PROTEIN S12, AND METHOD FOR PRODUCING PROTEIN IN CELL-FREE SYSTEM USING THE EXTRACT - It is intended to provide an extract, kit and a process for synthesizing a protein in a cell-free system. The extract is characterized by being prepared from mutant | 06-09-2011 |
| 20110129892 | PRODUCTION OF CELL TISSUE HAVING THREE-DIMENSIONAL STRUCTURE USING ELECTROSTATIC INK JET PHENOMENON - According to the present invention, a method and an apparatus for producing a cell tissue of blood vessels or the like with the use of an electrostatic ink jet phenomenon are provided. | 06-02-2011 |
| 20110129826 | METHOD FOR DETERMINATION OF INFLAMMATORY DISEASE BY USING SINGLE NUCLEOTIDE POLYMORPHISM IN BRCA1-RELATED PROTEIN (BRAP) GENE - It is an object of the present invention to identify a novel single nucleotide polymorphism (SNP) associated with the development and advancement of inflammatory diseases such as myocardial infarction. The present invention provides a method for judging inflammatory diseases, which comprises detecting at least one gene polymorphism in the BRCA1-associated protein (BRAP) gene. | 06-02-2011 |
| 20110111529 | METHOD FOR QUANTIFICATION OF ANTIGEN-SPECIFIC CANINE OR HUMAN IGE - Disclosed is a convenient and effective means for quantifying an antigen-specific canine or human IgE. Specifically disclosed is a method for quantifying an antigen-specific canine IgE, which comprises the following steps (A) to (D): (A) contacting a biological sample collected from a subject with an antigen to conjugate IgE contained in the sample with the antigen; (B) measuring the quantity of IgE in a standard sample collected from an experimental animal which is different from the subject and has been sensitized with the same antigen as that used in step (A) by using a substance capable of recognizing both IgE from the subject and IgE from the experimental animal, thereby producing a standard curve; (C) detecting a conjugate formed in step (A) by using the same substance capable of recognizing both IgE from the subject and IgE from the experimental animal as that used in step (B); and (D) determining the quantity of IgE in the biological sample collected from the subject by utilizing the quantity of the conjugate detected in step (C) and the standard curve produced in step (B). Also specifically disclosed is a method for quantifying an antigen-specific human IgE. | 05-12-2011 |
| 20110111446 | THIOL DETECTION METHOD - It is an object of the present invention to provide: a novel thiol-detecting reagent, which can be used in vivo and which solves the problem regarding the generation of background fluorescence due to hydrolysis; and a method for detecting thiol using the aforementioned reagent. The present invention provides a compound represented by the following formula (1): | 05-12-2011 |
| 20110104188 | NOVEL GLYCOLIPID AND USE THEREOF - The invention provides a glycolipid effective for cancer treatment and the like and a synthetic intermediate therefor, as well as a medicament containing the glycolipid and the like. The glycolipid is represented by the formula (1) or a salt thereof | 05-05-2011 |
| 20110097711 | METHOD OF JUDGING INFLAMMATORY DISEASE BY USING SINGLE NUCLEOTDIE POLYMORPHISM - An object of the present invention is to identify a novel single nucleotide polymorphism (SNP) associated with the onset and the advancement of inflammatory diseases such as myocardial infarction. The present invention provides a method for judging an inflammatory disease which comprises detecting at least 1 type of genetic polymorphism existing in at least one gene selected from the group consisting of the LBP-32 gene, the TSBP gene, and the WAP gene. | 04-28-2011 |
| 20110093985 | TRANSCRIPTION FACTOR FOR PROMOTING LATERAL ROOT GROWTH UNDER NITROGEN-LIMITING CONDITIONS - This invention provides a transcription factor AGL21 (AGAMOUS-LIKE 21), which can positively regulate the lateral root growth of a plant when the external supply of N is limited, a homologue thereof or a mutant thereof, gene encoding thereof and a transformed plant with the gene. | 04-21-2011 |
| 20110091869 | METHOD FOR CULTURE OF STEM CELL - The present invention enables efficient suspension culture of stem cells in a serum-free medium by comprising a step for quickly forming a homogenous aggregate of stem cells, and provides a method of selectively inducing the differentiation of nerves from a stem cell, a method of forming a cerebral cortical nerve network in vitro, and a method of producing a steric structure of a brain tissue in vitro, as well as a method of producing hypothalamic neuron progenitor cells, comprising culturing pluripotent stem cells as a suspended aggregate in a serum-free medium that substantially does not contain a Nodal signal promoter, a Wnt signal promoter, an FGF signal promoter, a BMP signal promoter, retinoic acid and an insulin, and isolating hypothalamic neuron progenitor cells from the culture. | 04-21-2011 |
| 20110087015 | Nucleoside and nucleotide having an unnatural base and use thereof - The object of the present invention is to provide a nucleoside or a nucleotide, or a derivative thereof, which has an unnatural base. The nucleoside and others of the present invention are characterized by having a 2-amino-6-(2-thiazolyl)purin-9-yl group or a 2-amino-6-(2-oxazolyl)purin-9-yl group as a base, wherein the 4- and/or 5-position of the thiazolyl or oxazolyl group may be substituted. | 04-14-2011 |
| 20110076704 | Method for diagnosing alzheimer's disease using serum glycoprotein as biomarker - It is an object of the present invention to detect a change in the metabolism of a glycoprotein having an α2,6-sialyl residue, which is contained in blood, so as to provide an agent and a method for diagnosing sporadic Alzheimer's disease. The present invention provides an agent for diagnosing Alzheimer's disease, which comprises lectin used for detecting an α2,6-sialyl residue-containing glycoprotein. | 03-31-2011 |
| 20110076680 | FLUORESCENT MOLECULE - It is an object of the present invention to provide an on-off type fluorescent compound (a fluorescence-producing molecule system) used in gene analyses, which is highly stable (namely, being active for a long period of time) and highly sensitive, and which enables amplification of a trace amount of gene signal and observation thereof. The present invention provides a nonfluorescent molecule having a fluorescent substance skeleton such as fluorescein skeleton and having a group represented by —O—C(Y1)(Y2)-N | 03-31-2011 |
| 20110071278 | ANTIBODIES THAT RECOGNIZE CUTTING EDGE WITHIN THE TGF- BETA ACTIVATION CONTROLLING REGION - It is an object of the present invention to provide antibodies capable of detecting an active TGF-β generation reaction that is specific to pathogenesis, tissues, or isoforms. The present invention provides antibodies against an LAP fragment (or latent TGF-β) generated as a result of generation of active form of human TGF-β1, human TGF-β2 and human TGF-β3. The antibodies are able to specifically recognize respective cutting edges within protease cleavage sites existing in the region from the amino acid residue glycine at position 51 to the amino acid residue arginine at position 110 of human TGF-β1, and corresponding regions of human TGF-β2 and human TGF-β3. | 03-24-2011 |
| 20110065126 | SUBSTANCE-IMMOBILIZING SUBSTRATE, SUBSTANCE-IMMOBILIZED SUBTRATE, AND ANALYSIS METHOD - The present invention relates to a substance-immobilizing substrate for immobilizing a substance to be detected by chemiluminescence. The substance-immobilizing substrate of the present invention comprises a metal portion composed of at least one metal selected from the group consisting of chromium and molybdenum, or an alloy of the metal on at least a portion of a surface of the substrate. The present invention further relates to a substance-immobilized substrate wherein a substance is immobilized on the substance-immobilizing substrate. The substance is immobilized on the metal portion and the substrate is used for detecting the immobilized substance by chemiluminescence. The present invention further relates to an analysis method comprising directly or indirectly detecting by chemiluminescence a substance that is immobilized on a substrate. The substrate comprises a metal portion composed of at least one metal selected from the group consisting of chromium and molybdenum, or an alloy of the metal on at least a portion of a surface of the substrate, and the substance is immobilized on the metal portion. | 03-17-2011 |
| 20110065102 | OSTEOARTHRITIS-SENSITIVE GENE - It is an object of the present invention to provide a method and kit for diagnosing osteoarthritis which involves genetic diagnosis or hemodiagnosis. The present invention provides a method for diagnosing a genetic susceptibility of a subject to osteoarthritis, which comprises detecting at least one polymorphism selected from polymorphisms existing in a gene (Dual Intracellular on Willebrand factor A gene; DIVA gene), encoding the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence substantially homologous thereto, in a DNA-containing sample collected from the subject, wherein an allele frequency of one of alleles is higher in arbitrary osteoarthritis group than in arbitrary non-osteoarthritis group. | 03-17-2011 |
| 20110064662 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY - Disclosed is a kit for use in the production of a molecular probe for PET drug screening for the purpose of producing a compound containing a short-lived radionuclide for PET applications. Specifically disclosed is a kit comprising a compound represented by the formula (I), (II) or (III) or a salt thereof. In the formulae, X | 03-17-2011 |
| 20110059869 | Method for Increasing Enzymatic Reactivity - An object of the invention is to provide a method for increasing enzymatic reactivity to a target substance immobilized on a support; and a method for reducing or suppressing an inhibitory effect of a support on enzymatic reaction. The above object is achieved by a method for increasing enzymatic reactivity to a target substance immobilized on a support by allowing at least one substance selected from the group consisting of saccharides, amino acids, polyhydric alcohols and derivatives thereof to exist; and a method for reducing or suppressing an inhibitory effect of a support immobilized with a target substance on enzymatic reactivity to the target substance by allowing at least one substance selected from the group consisting of saccharides, amino acids, polyhydric alcohols and derivatives thereof to exist. | 03-10-2011 |
| 20110059868 | PROCESS FOR AMPLIFYING NUCLEIC ACIDS - The present invention relates to a process for synthesizing or amplifying efficiently a nucleic acid comprising a target nucleic acid sequence. In the process according to the present invention, a primer comprising in its 3′-end portion a sequence (Ac′) which hybridizes a sequence (A) in the 3′-end portion of the target nucleic acid sequence, and in the 5′-side of said sequence (Ac′) a sequence (B′) which hybridizes the complementary sequence (Bc) of a sequence (B) positioned in the 5′-side of said sequence (A) on the target nucleic acid sequence, wherein {X−(Y−Y′)}/X is in the range of −1.00 to 1.00, in which X denotes the number of bases in said sequence (Ac′), Y denotes the number of bases in the region flanked by said sequences (A) and (B) in the target nucleic acid sequence, and Y′ denotes the number of bases in an intervening sequence between said sequences (Ac′) and (B′) (Y′ may be zero). | 03-10-2011 |
| 20110058155 | MOBILITY MEASURING APPARATUS, METHOD THEREFOR, AND RESISTIVITY MEASURING APPARATUS AND METHOD THEREFOR - A mobility measuring apparatus includes a storage unit that respectively stores a relationship between the mobility μ of carriers in a semiconductor and a decay constant γ of the carriers and a relationship between a reflectivity R of the semiconductor to a terahertz light and the decay constant γ of the carriers, a light radiating unit that radiates a terahertz light to the semiconductor as a sample, a detecting unit that detects a reflected light of the sample to the radiated terahertz light, a reflectivity calculating unit that calculates the reflectivity R | 03-10-2011 |
| 20110057109 | MONOCHROMATIC WAVELENGTH VARIABLE TERAHERTZ WAVE GENERATION/DETECTION SYSTEM AND METHOD - To provide a monochromatic wavelength variable terahertz wave generation/detection system that has high detection sensitivity at room temperature and that can quickly operate at the same time, excitation light of monochromatic wavelength generated from one excitation light source is inputted to a wavelength variable terahertz wave source and a nonlinear light conversion terahertz wave detector through an excitation light phase control optical system shown below. The excitation light phase control optical system includes, on a light path of the excitation light, an optical element capable of simultaneously changing an incidence angle of the excitation light to a generation point of a terahertz wave in the wavelength variable terahertz wave source and an incidence angle of the excitation light to an incidence point of the terahertz wave in the nonlinear light conversion terahertz wave detector to set both the generation point and the incidence point at the same time on the focal points in a confocal optical system. | 03-10-2011 |
| 20110053782 | NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY - The present invention relates to unnatural base pairs of Ds (a 5-amino-7-(2-thienyl)-3H-imidazo[4,5-b]pyridine-3-yl group) and a Pa derivative (a 2-nitro-1H-pyrrole-1-yl group bearing a substituent having a π-electron system attached at position 4) that can be replicated with high selectivity/high efficiency, and methods for replicating nucleic acids containing the unnatural base pairs. The present invention also relates to methods for incorporating an unnatural base bearing a functional substituent attached thereto into DNA by a nucleic acid replication reaction. The present invention also relates to methods for replicating and selectively collecting a nucleic acid containing an unnatural base pair from a nucleic acid pool. The present invention also relates to methods for determining a sequence of natural bases in the proximity of an unnatural base in DNA for achieving highly efficient and highly selective replication of a nucleic acid containing the unnatural base. | 03-03-2011 |
| 20110052598 | METHOD FOR SCREENING OF THERAPEUTIC AGENT FOR ALLERGIC AIRWAY INFLAMMATION AND/OR AIRWAY HYPERSENSITIVITY USING IL-17RB-POSITIVE NKT CELL - The invention provides a method of screening a therapeutic agent for allergic airway inflammation and/or airway hypersensitivity, comprising using an IL-17RB positive NKT cell, as well as a therapeutic agent for allergic airway inflammation and/or airway hypersensitivity, containing a substance capable of inhibiting or eliminating the Th2 cell-like function of an IL-17RB positive NKT cell as an active ingredient. | 03-03-2011 |
| 20110042713 | NITRIDE SEMI-CONDUCTIVE LIGHT EMITTING DEVICE - The nitride semi-conductive light emitting layer in this invention comprises a single crystal substrate | 02-24-2011 |
| 20110039912 | Therapeutic Agent for Neuroblastoma Targeting ARID3b - It is intended to provide a therapeutic agent for neuroblastoma. More particularly, it is intended to provide the therapeutic agent for neuroblastoma containing an ARID3b inhibitor. | 02-17-2011 |
| 20110038032 | TERAHERTZ WAVE GENERATING METHOD AND APPARATUS - A first laser beam 1 | 02-17-2011 |
| 20110037001 | TERAHERTZ BEAM SCANNING APPARATUS AND METHOD THEREOF - To provide a terahertz beam scanning apparatus and method that can scan a terahertz beam at high speed over a wide angle. The terahertz beam scanning apparatus includes: a laser device | 02-17-2011 |
| 20110023189 | TRANSFORMED PLANT WITH PROMOTED GROWTH - The present invention is directed to identify genes involved in the growth of a plant and provide a transformed plant the growth of which is promoted utilizing the genes. | 01-27-2011 |
| 20110021346 | POLYMERIZATION CATALYST COMPOSITION FOR POLYMERIZATION OF ISOPRENE COMPOUND - 3,4-isoprene-based polymer having high isotacticity can be produced by polymerizing an isoprene compound using a complex represented by the general formula (A) and a catalyst activator: | 01-27-2011 |
| 20110020932 | IN VITRO DIFFERENTIATION/INDUCTION OF LYMPHOCYTE FROM STEM CELL HAVING GENOTYPE PROVIDED AFTER GENE RECONSTITUTION - The present invention provides a production method of a functional differentiated cell having a post-rearrangement genotype of a particular antigen receptor gene, which includes culturing a stem cell having the genotype in a medium to give the differentiated cell derived from the stem cell. As the stem cell having the genotype, a stem cell (e.g., ES cell) established by transplantation of the nucleus of a cell having the genotype is preferable. As the differentiated cell, NKT cell is preferable. | 01-27-2011 |
| 20110004240 | VISIBLE LIGHT CURABLE ADHESIVE - An object of the present invention is to provide a water soluble bioadhesive that is curable by visible light irradiation. The present invention provides a visible light curable adhesive, which comprises a water soluble oxygen sensitizer that generates radicals under visible light irradiation and a water soluble polymer compound having a functional group that can be activated via singlet oxygen generated from the oxygen sensitizer under visible light irradiation. | 01-06-2011 |
| 20100330057 | METHOD OF EVALUATING HUMAN DENTRITIC CELLS AND HUMAN CELL IMMUNOTHERAPEUTIC AGENT - The invention provides a method of evaluating the antigen presentation potential of human dendritic cells by administering α-galactosylceramide-pulsed human dendritic cells to a non-human mammal; collecting a sample containing NKT cells from the non-human mammal; and detecting the activation of NKT cells present in the sample. The invention further provides an agent for human NKT cell immunotherapy, which contains human dendritic cells that have been assessed by the aforementioned method as those possessing an antigen presentation potential for NKT cells. | 12-30-2010 |
| 20100323364 | MODIFIED tRNA CONTAINING UNNATURAL BASE AND USE THEREOF - In the method for introducing a noncanonical amino acid residue into a desired position in a protein, the structure of tRNA is so modified as to have improved affinity for aminoacyl-tRNA synthetase or improved specificity to aminoacyl-tRNA synthetase. An unnatural base is contained at any position in tRNA, whereby the efficiency of aminoacylation of the tRNA with a noncanonical amino acid can be improved. | 12-23-2010 |
| 20100323346 | Method of Examining Inflammatory Disease and Method of Screening Remedy for Inflammatory Disease - A single nucleotide polymorphism occurring on a leptin receptor gene is analyzed and an inflammatory disease is examined on the basis of the analytical data. Further, a substance capable of changing the interaction between the leptin receptor and galectin-2 is selected to thereby screen a remedy for an inflammatory disease. | 12-23-2010 |
| 20100312375 | ARTIFICIAL BONE FORMING METHOD BY POWDER LAMINATION METHOD - An artificial bone forming method, comprising a) a powder layer forming step ( | 12-09-2010 |
| 20100311608 | METHOD TO PREPARE MAGNETIC BEADS CONJUGATED WITH SMALL COMPOUNDS - It is an object of the present invention to provide a method for stably and efficiently binding a compound to magnetic beads. The present invention relates to a method for producing compound-bound magnetic beads, which comprises: allowing a compound to come into contact with magnetic beads, on the surface of each of which a photoreactive compound has bound; extending the magnetic beads together with the compound on a support; and applying light to the magnetic beads to form a covalent bond between the photoreactive compound and the compound. | 12-09-2010 |
| 20100304497 | FLUORESCENT PROTEIN AND CHROMOPROTEIN - It is an object of the present invention to provide a novel chromoprotein and a novel fluorescent protein. The present invention provides chromoproteins derived from | 12-02-2010 |
| 20100292454 | NEURONAL REGENERATION PROMOTING AGENT - It is an object of the present invention to provide a novel neuronal regeneration promoting agent, particularly a neuronal regeneration promoting agent having an inhibitory effect on glial scar formation. The present invention provides a neuronal regeneration promoting agent which comprises an inhibitor of a bone morphogenetic protein type 1A receptor (BMPR1A) as an active ingredient. | 11-18-2010 |
| 20100285598 | Novel Artificial Base Pairs and Uses Thereof - The present invention provides nucleic acids based on novel artificial base pairing, as well as a preparation method and uses thereof. | 11-11-2010 |
| 20100284880 | PROTON CONDUCTING MEMBRANE AND METHOD FOR PRODUCING PROTON CONDUCTING MEMBRANE - A proton conducting membrane comprising, as a main component, a ceramic structure in which an oxygen atom of a metal oxide is bonded through the oxygen atom with at least one group derived an oxygen acid selected from —B(O) | 11-11-2010 |
| 20100280095 | THERAPEUTIC AGENT FOR WOUNDS AND SCREENING METHOD FOR THE SAME - The present invention provides an agent for treating wound, containing a substance that suppresses the expression or function of PDLIM2. The substance that suppresses the expression or function of PDLIM2 is preferably an siRNA or antisense nucleic acid capable of specifically suppressing the expression of PDLIM2, or an expression vector capable of expressing said polynucleotide. In addition, the present invention provides a method of screening for a substance capable of treating wounds, including determining whether or not a test substance is capable of suppressing the expression or function of PDLIM2. | 11-04-2010 |
| 20100271618 | CARRIER CONCENTRATION MEASURING DEVICE AND CARRIER CONCENTRATION MEASURING METHOD - A nondestructive carrier concentration measuring device ( | 10-28-2010 |
| 20100267087 | MUTANT PYRROLYSYL-tRNA SYNTHETASE, AND METHOD FOR PRODUCTION OF PROTEIN HAVING NON-NATURAL AMINO ACID INTEGRATED THEREIN BY USING THE SAME - Method for incorporating a lysine derivative (particularly an N | 10-21-2010 |
| 20100249477 | Method of Rapid Methylation, Kit for Preparing PET Tracer and Method of Producing PET Tracer - It is intended to provide a method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a mild condition rapidly in high yield using an organic boron compound whose toxicity is not so high as a substrate; a kit for preparing a PET tracer to be used in the same, and a method of producing a PET tracer using the same. In an aprotic polar solvent, methyl iodide or X—CH2F (wherein X is a functional group which can be easily released as an anion), an organic boron compound in which an aromatic ring or an alkenyl group is attached to boron are subjected to cross-coupling in the presence of a palladium(0) complex, a phosphine ligand, and a base. | 09-30-2010 |
| 20100240284 | DEVICE AND METHOD FOR ELID HONING - An ELID honing device includes a honing tool | 09-23-2010 |
| 20100239501 | GENE SENSITIVE TO BONE/JOINT DISEASE AND USE THEREOF - The present invention provides a suppressing agent for inflammatory cytokine expression in joints and/or joint destruction (e.g., articular cartilage destruction) and/or pain in a bone/joint disease, comprising a substance that suppresses the expression or activity of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence shown by SEQ ID NO:2, a screening method for a substance that regulates inflammatory cytokine expression in joints and/or joint destruction (e.g., articular cartilage destruction) and/or pain in a bone/joint disease, comprising using the protein or a partial peptide thereof, and a diagnostic method for genetic susceptibility to a bone/joint disease, comprising detecting a polymorph in the base shown by base number 24007 in the partial base sequence of the human EDG2 gene shown by SEQ ID NO:3. | 09-23-2010 |
| 20100233684 | METHOD FOR DETERMINING INFLAMMATORY DISEASE - It is an object of the present invention to provide a method for determining inflammatory diseases including myocardial infarction as a typical example, which involves identifying polymorphisms associated with myocardial infarction and using the gene polymorphisms, an oligonucleotide that can be used for the method, a kit for diagnosing inflammatory diseases, a therapeutic agent for inflammatory diseases, and the like. The present invention provides a method for determining an inflammatory disease, which comprises detecting at least one type of gene polymorphism existing in a proteasome subunit α type 6 gene. | 09-16-2010 |
| 20100233215 | IMMUNOTHERAPY BY USING CELL CAPABLE OF CO-EXPRESSING TARGET ANTIGEN AND CD1d AND PULSED WITH CD1d LIGAND - The present invention provides a novel immunity induction method, particularly, a method of simultaneously inducing activation of NKT cells and T-cell immune responses. To be more precise, the present invention provides a target antigen and CD1d co-expressing cell, and a preparation and identification method thereof; a target antigen and CD1d co-expressing cell capable of activating immunity to the target antigen, and a preparation method thereof; an immunoinducer to a target antigen or a pharmaceutical agent, which contains a target antigen and CD1d co-expressing cell capable of activating immunity to the target antigen; a target antigen and CD1d co-expressing vector; a kit containing an expression vector and/or a CD1d ligand; and the like. | 09-16-2010 |
| 20100227383 | GENE DETECTION AND DETERMINATION APPARATUS, GENE REACTOR, AND INCUBATOR - A genetic detection and determination apparatus which detects or determines genetic information, provided with a reaction container having a reaction vessel, including: a container set portion on which the reaction container is set; a moving mechanism which moves the container set portion along a track; a reaction vessel dividing portion which divides the reaction vessel into a plurality of reaction chambers by deforming the reaction vessel; a heating and cooling portion which heats and cools the reaction container; and a measuring portion which is movable above the container set portion in parallel to an upper surface of the reaction container provided on the container set portion and which measures a reaction within each of the reaction chambers. | 09-09-2010 |
| 20100221807 | CELLULASE ENZYME AND METHOD FOR PRODUCING THE SAME - This invention provides a cellulase enzyme derived from intestinal symbiotic protists of insects selected from the group consisting of | 09-02-2010 |
| 20100221787 | ISOTHERMAL AMPLIFICATION METHOD AND DNA POLYMERASE USED IN THE SAME - A DNA polymerase suitable for specific isothermal amplification methods and an isothermal amplification method using the DNA polymerase are provided. In the presence of a DNA polymerase including a protein described in the following item (a) or (b), an amplification reaction of a target nucleic acid sequence in a nucleic acid sample is carried out isothermally using a first primer shown in the following (X). By using the DNA polymerase, it becomes possible to carry out the amplification reaction using the primer within a shorter time than ever before.
| 09-02-2010 |
| 20100221704 | Method of Dispensing Nonvolatile Liquid in Reaction Vessel and Reaction Vessel Processing Apparatus - It is intended to easily dispense a minute amount of nonvolatile liquid. In a preferred embodiment, in dispensing of mineral oil (nonvolatile liquid), dispensing is conducted in the condition that the amount of air contained in a tip ( | 09-02-2010 |
| 20100217733 | NEURON DEVICE, NEURAL NETWORK DEVICE, FEEDBACK CONTROL DEVICE, AND INFORMATION RECORDING MEDIUM - In order to utilize variable neuron thresholds and extended Hebb's rule in a neural network for proper control, a neuron device ( | 08-26-2010 |
| 20100207136 | SAPPHIRE SUBSTRATE, NITRIDE SEMICONDUCTOR LUMINESCENT ELEMENT USING THE SAPPHIRE SUBSTRATE, AND METHOD FOR MANUFACTURING THE NITRIDE SEMICONDUCTOR LUMINESCENT ELEMENT - The present invention provides an inexpensive substrate which can realize m-plane growth of a crystal by vapor phase growth. In a sapphire substrate, an off-angle plane slanted from an m-plane by a predetermined very small angle is prepared as a growth surface, which is a template of the crystal, at the time of growing a crystal of GaN or the like, by a polishing process to prepare a stepwise substrate comprising steps and terraces. According to the above-described configuration, even if an inexpensive sapphire substrate, which normally does not form an m-plane (nonpolar plane) GaN film, is used as a substrate for crystal growth, the following advantages can be attained. Specifically, c-axis growth can be carried out from the plane of each step as an a-plane on the terrace by vapor phase growth, which is advantageous in the fabrication of a device, in order to grow an excellent GaN single crystal which has been epitaxially grown so that the m-plane is opposite to the surplane of the terrace, and, in the mean time, the steps become integrated (fused), whereby a device can be fabricated from a substrate of a GaN single crystal having no significant threading dislocation. Further, the use of the m-plane can advantageously eliminate the influence of piezo electric fields. | 08-19-2010 |
| 20100200755 | APPARATUS AND METHOD FOR DETECTING TERAHERTZ WAVE - A terahertz wave detecting apparatus includes a semiconductor chip | 08-12-2010 |
| 20100199387 | GENE HAVING ENDOREDUPLICATION PROMOTING ACTIVITY - This invention is intended to identify a gene that regulates endoreduplication in a plant and to use such gene for breeding aimed at increasing the crop size. This invention provides a gene encoding an Arabidopsis thaliana-derived protein having an amino acid sequence as shown in SEQ ID NO: 2, 4, 6, 8, 10, or 12, which has endoreduplication promoting activity, a transgenic plant into which such gene has been introduced, thereby increasing the nuclear DNA content in the cells of such plant, and a method of using such gene to increase the size of the entire plant or a part thereof. | 08-05-2010 |
| 20100196209 | Method of Dispensing in Reaction Vessel and Reaction Vessel Processing Apparatus - It is intended to facilitate dispensing of a minute amount of a nonvolatile liquid. In a preferred embodiment, in dispensing of mineral oil ( | 08-05-2010 |
| 20100190159 | FLUORESCENCE-PRODUCING MOLECULE - It is an object of the present invention to provide an on-off type fluorescent compound used in gene analyses, which is highly stable and highly sensitive, and which enables amplification of a trace amount of gene signal and observation thereof. The present invention provides a compound represented by the following formula (1) or (2): | 07-29-2010 |
| 20100184116 | FLUORESCENT PROTEIN - The present invention provides a fluorescent protein having an amino acid sequence of the green fluorescent protein, the yellow fluorescent protein or mutants thereof wherein the 46 | 07-22-2010 |
| 20100178359 | FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING INORGANIC COPPER COMPOUND AS ACTIVE INGREDIENT - Disclosed is a fungicide for agricultural and horticultural use which is characterized by containing an inorganic copper compound and a polymer thickener having a sulfonyl group. This fungicide for agricultural and horticultural use exhibits higher plant disease-control effects than conventional inorganic copper-based fungicides. | 07-15-2010 |
| 20100168389 | PROCESS FOR PRODUCING EXTRACT FOR CELL-FREE PROTEIN SYNTHESIS AND CELL EXTRACT PRODUCED THEREBY - It is intended to provide a process for producing an extract for cell-free protein synthesis whereby the productivity of a protein and the production efficiency can be improved. Cells are cultured under suppressed growth conditions. In the stationary phase of the culture, the cells are collected and then disrupted. The above-described cells are preferably bacterial cells, in particular, | 07-01-2010 |
| 20100167398 | METHOD OF CULTURING PLURIPOTENT STEM CELLS USING EXTRACELLULAR MATRIX FROM FETAL MEMBRANE-DERIVED CELLS - Provided are a method of culturing pluripotent stem cells in the presence of a decidua-derived cell or an extracellular matrix derived from the cell, that enables safe and efficient maintenance culture and derivation of pluripotent stem cells; a culture agent for pluripotent stem cells, that comprises a decidua-derived cell or an extracellular matrix derived from the cell; and other means for developing or performing the method. | 07-01-2010 |
| 20100151514 | NOVEL MUCIN-TYPE GLYCOPROTEIN AND USE THEREOF - Provided is a novel mucin-type glycoprotein and a method for producing the same. Specifically, a mucin-type glycoprotein having a repeat structure including 3 to 2000 repeating units each having an amino acid sequence represented by the formula I: Val-Xaa-Glu-Thr-Thr-Ala-Ala-Pro [wherein Xaa represents Val or Ile] (SEQ ID NO: 1), wherein one or more amino acid residues in the structure are bound to a sugar chain of one or more monosaccharides. Also provided is a composition containing the novel mucin-type glycoprotein. Further provided is a molecular weight marker containing the novel mucin-type glycoprotein. | 06-17-2010 |
| 20100144078 | OPTICAL SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREFOR - To provide an elemental technique for improving the emission intensity of deep ultraviolet light from a light emitting layer made of an AlGaInN-based material, in particular, an AlGaN-based material. First, an AlN layer is grown on a sapphire surface. The AlN layer is grown under a NH | 06-10-2010 |
| 20100137407 | SINGLE-CHAIN CIRCULAR RNA AND METHOD OF PRODUCING THE SAME - The present invention relates to a single-chain circular RNA having a sustained or slow-releasing RNA interference effect, characterized in that the single-chain circular RNA comprises a sense strand sequence, an antisense strand sequence complementary to the sense strand sequence, identical or different two loop sequences between the sense strand and the antisense strand, connecting both strands, wherein the sense strand and the antisense strand are paired to form a stem. | 06-03-2010 |
| 20100129339 | NKT CELL-STIMULATING AGENT FOR ADMINISTRATION THROUGH UPPER RESPIRATORY TRACT MUCOUS MEMBRANE - The present invention provides an NKT cell stimulating agent containing antigen-presenting cells pulsed with an NKT cell ligand, to be administered submucosally in the upper airway. By submucosal administration in the upper airway, it is possible to stimulate NKT cells and stimulate immune reactions extremely efficiently with a small number of NKT cell ligand-pulsed antigen-presenting cells. By submucosal administration in the upper airway, NKT cells can be induced selectively in cervical lymph nodes. | 05-27-2010 |
| 20100105137 | METHOD FOR INDUCTION/DIFFERENTIATION INTO PHOTORECEPTOR CELL - The present invention provides a method of producing primate retinal progenitor cells, comprising culturing primate embryonic stem cells as suspended aggregates in a serum-free medium, and obtaining retinal progenitor cells from the culture. The present invention further provides a method of producing photoreceptor precursor cells, comprising culturing isolated retinal progenitor cells differentiated from embryonic stem cells, under adhesive conditions, in the presence of a gamma secretase inhibitor, and obtaining a photoreceptor precursor from the culture. | 04-29-2010 |
| 20100104632 | Drug Having Regulatory Cell Ligand Contained in Liposome - A liposome containing a regulatory cell ligand such as α-galactosyl ceramide or β-galactosyl ceramide is employed as the active ingredient of a drug for preventing or treating immune diseases etc. | 04-29-2010 |
| 20100092971 | COMPOUND HAVING STRUCTURE DERIVED FROM MONONUCLEOSIDE OR MONONUCLEOTIDE, NUCLEIC ACID, LABELING SUBSTANCE, AND METHOD AND KIT FOR DETECTION OF NUCLEIC ACID - The present invention provides, for example, a labeling substance that allows the double helix structure of a nucleic acid to be detected effectively. The present invention provides a compound having a structure derived from mononucleoside or mononucleotide, with the structure being represented by the following formula (1), (1b), or (1c), a tautomer or stereoisomer thereof, or a salt thereof. | 04-15-2010 |
| 20100083393 | METHOD OF CONSTRUCTING CLONE MAMMAL - The present invention provides a method of producing a cloned mammal, which uses a mammalian natural killer T cell as a donor cell, a cloned mammal obtained by the method, a method of obtaining an ES cell from the embryo of the cloned animal and an ES cell obtained by the method. | 04-01-2010 |
| 20100078639 | THIN FILM SEMICONDUCTOR DEVICE FABRICATION METHOD AND THIN FILM SEMICONDUCTOR DEVICE - The present invention provides a method for making a thin film semiconductor device having a bottom-gate, bottom-contact-type thin film transistor structure finer in size with satisfactory characteristics, in which the interface between a gate insulating film and a thin film semiconductor layer can be maintained at satisfactory conditions without being affected by formation of source/drain electrodes. A first gate insulating film ( | 04-01-2010 |
| 20100075193 | Proton Conductive Membrane and Method for Producing it - A proton conductive membrane having high proton conductivity is provided. | 03-25-2010 |
| 20100068807 | INTERFERON-alpha REGULATOR - An object of the present invention is to elucidate the role of IKKα in TLR signaling and provide an agent and a method for controlling interferon-α. The present invention provides an agent for suppressing interferon-α production which comprises an agent for inhibiting IKKα. | 03-18-2010 |
| 20100062990 | NOVEL PSEUDOGLYCOLIPID AND USE THEREOF - The invention provides a pseudoglycolipid effective for cancer treatment and the like and a novel synthesis intermediate therefor, as well as a medicament containing the pseudoglycolipid and the like. The inventive compound is represented by the formula (1), or a salt thereof, | 03-11-2010 |
| 20100058906 | METHOD FOR CUTTING FERROUS MATERIAL AND CUTTING FLUID SUPPLY DEVICE - In a method for cutting ferrous material in accordance with the present invention, a water-soluble cutting fluid containing nanometer-size carbon particles is electrolyzed, and a ferrous workpiece is cut by a diamond cutting tool | 03-11-2010 |
| 20100058497 | EARLY-MATURING TRANSFORMED PLANT - The present invention provides an early-maturing transgenic plant, which comprises a nucleic acid that encodes a protein having activity of causing early maturation of a plant, so that the gene can be expressed. | 03-04-2010 |
| 20100051812 | METHOD AND APPARATUS FOR DETECTING TERAHERTZ WAVES - A terahertz wave detecting apparatus includes a semiconductor chip | 03-04-2010 |
| 20100036111 | METHOD FOR REPLICATING NUCLEIC ACIDS AND NOVEL UNNATURAL BASE PAIRS - The present invention relates to a method for nucleic acid replication and novel artificial base pairs. | 02-11-2010 |
| 20100035360 | REAGENT FOR DETECTION OF AUTOANTIBODY AND KIT FOR DIAGNOSIS OF AUTOIMMUNE DISEASE - This invention is intended to discover a novel autoantibody that can be used as a marker for an autoimmune disease and to provide an effective means for diagnosing an autoimmune disease. Disclosed is a reagent for detecting an autoantibody comprising an inositol 1,4,5-trisphosphate receptor (IP | 02-11-2010 |
| 20100035249 | RNA SEQUENCING AND ANALYSIS USING SOLID SUPPORT - The present invention provides methods for the sequencing of all RNA species within an RNA sample, such as the RNA content obtained from a cell, a tissue, a living organism, or from an artificial source. RNA molecules within the samples are labeled in a RNA-specific manner prior to immobilization on a solid support. One label is used to mark the location of the RNA molecule on the solid support, whereas the second label is used to mark selectively the S′ end of full-length mRNA molecules. RNA molecules are sequenced while being bound to the solid support in one or more sequencing reactions, and sequences of individual RNA molecules can be forwarded to computational analysis for assembling sequence information from individual sequencing reads obtained from the same location on the solid support. Not only unsupervised expression profiling on a genome-wide scale, but also the direct analysis of RNA-RNA interactions become possible as revealed by the analysis of the sequencing information obtained along with genomic information. | 02-11-2010 |
| 20100028985 | Reaction Vessel, Reaction Vessel Processing Apparatus and Diagnostic Apparatus - A reaction vessel suitable for automating of various measurements is provided. In a preferred embodiment, on the same side of plate-like substrate ( | 02-04-2010 |
| 20100028329 | METHOD FOR PRODUCING GLYCOSYLATED INDOLE COMPOUND AND ANTIBODY AGAINST THE COMPOUND - This invention provides a method of producing a large amount of an α-form or β-form of N-pyranosyl-tryptophan having a specified structure and preparing an antibody therefrom. The method comprises a step of allowing a pyranose compound to react with a 3-pyrazyl-indole compound in the presence of a first base to obtain a 1-pyranosyl-3-pyrazyl-indole compound, and a step of treating the 1-pyranosyl-3-pyrazyl-indole compound with an acid, treating the resultant with a hydrogenation catalyst, and further treating the resultant with a second base to synthesize N-pyranosyl-tryptophan, thereby producing an antibody therefrom. | 02-04-2010 |
| 20100016221 | METHOD OF DEGRADING PROTEIN BY CHAPERONE-MEDIATED AUTOPHAGY - The present invention provides a method of degrading a target protein in a subject comprising administrating to the subject an effective amount of any of: (a) a peptide comprising an HSC70-binding moiety and a target protein-binding moiety; and/or (b) a polynucleotide encoding the peptide of (a). | 01-21-2010 |
| 20100008857 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND - A label with which labeling is easy when labeling a molecule, i.e., a label that has a high reaction rate upon labeling and that produces a high reaction yield, as well as a precursor for the production of the label are provided. This is achieved by a hexatriene-β-carbonyl compound represented by Formula (I), a hexatriene-β-carbonyl compound represented by Formula (II), a hexatriene-β-carbonyl compound represented by Formula (III) and a hexatriene-β-carbonyl compound represented by Formula (IV). | 01-14-2010 |
| 20100006892 | NEAR-FIELD TERAHERTZ WAVE DETECTOR - A near-field terahertz wave detector comprises a semiconductor chip ( | 01-14-2010 |
| 20090317863 | USE OF ACTIVE CYTOKININ SYNTHASE GENE - It is an object of the present invention to clarify an enzyme gene capable of directly regulating the amount of active cytokinins synthesized and to provide a transformed plant with a regulated amount of cytokinins using the aforementioned gene. | 12-24-2009 |
| 20090317862 | Cell-free protein synthesis system for synthesizing glycoprotein - Provided is a process for producing a protein with post-translational modification in a cell-free protein synthesis system having a higher protein synthetic activity and glycosylation capability. The process of the present invention comprises preparing a cell extract from cultured cells of an immortalized mammalian cell line that has enhanced protein secreting activity, and adding an mRNA encoding a glycoprotein to the cell extract. | 12-24-2009 |
| 20090298775 | METHOD OF MEASURING NEPRILYSIN ACTIVITY - The present invention provides a method of measuring the activity of neprilysin, etc. More specifically, the present invention provides a method of measuring the activity of neprilysin in nerve cells; a method of screening a protein, a peptide or a compound enhancing the activity or expression of neprilysin in nerve cells by measuring the activity of neprilysin; a method of enhancing the activity or expression of neprilysin; and so on. Thus, the compound enhancing the activity and/or expression of neprilysin, which is obtained by the screening method characterized by using the method of measuring the activity of neprilysin in accordance with the present invention, is useful as a preventive and/or therapeutic agent for Alzheimer's disease. The method of measuring the activity of the present invention can be used for presymptomatic diagnosis of Alzheimer's disease. | 12-03-2009 |
| 20090291852 | Method for Amplification of Nucleotide Sequence - A method for amplification of a nucleotide sequence characterized by performing PCR amplification using mRNA isolated from a biological sample as a template and using a first primer comprising a poly(T) sequence and an additional nucleotide sequence X thereto and a second primer comprising a poly(T) sequence and an additional nucleotide sequence Y thereto, provided that the nucleotide sequences X and Y in the first and second primers, respectively, have different sequences from each other. | 11-26-2009 |
| 20090286936 | COMPOSITION FOR FORMATION OF MOLD - Disclosed is a composition for formation of a mold, which is used in a method for producing a nanostructure by removing a portion of a thin film formed on the surface of a mold, and removing the mold, the composition including an organic compound, which has a hydrophilic group and has a molecular weight of 500 or more. | 11-19-2009 |
| 20090286877 | PESTICIDAL/OVICIDAL COMPOSITION AND PESTICIDAL/OVICIDAL METHOD - A pesticidal/ovicidal composition comprising (a) 50-99.9 parts by mass of a triglyceride containing not less than 50% of oleic acid as a fatty acid component; (b) 0.1-20 parts by mass of a nonionic surface active agent; and (c) 0-30 parts by mass of a glycerin derivative. The composition according to the invention has not only a pesticidal activity but also an ovicidal activity on crop pests, and provides a safe and high pesticidal/ovicidal effect. | 11-19-2009 |
| 20090286319 | MICROINJECTION METHOD AND DEVICE - An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method. | 11-19-2009 |
| 20090286311 | DNA sequences for the expression of alloproteins - The present invention discloses an expression method for non-naturally-occurring amino acid-containing protein comprising: expressing in animal cells: (A) a mutant tyrosyl-tRNA synthetase that is a mutation of tyrosyl-tRNA synthetase originating in | 11-19-2009 |
| 20090282582 | ENVIRONMENTAL STRESS RESPONSIVE PROMOTER AND METHOD OF TISSUE-SPECIFIC GENE EXPRESSION USING THE SAME - This invention concerns induction of gene expression specifically in given tissue with the use of a novel promoter that has environmental stress responsiveness and functions specifically in given tissue. It is realized by a method comprising: a step of preparing a plant having an arbitrary gene downstream of the environmental stress responsive promoter comprising DNA (a), (b), or (c) below; (a) DNA comprising the nucleotide sequence as shown in any of SEQ ID NO: 1 to 8; (b) DNA comprising a nucleotide sequence derived from the nucleotide sequence as shown in any of SEQ ID NO: 1 to 8 by deletion, substitution, or addition of one or a plurality of nucleotides and functioning as an environmental stress responsive promoter; or (c) DNA hybridizing under stringent conditions to DNA comprising the nucleotide sequence as shown in any of SEQ ID NO: 1 to 8 and functioning as an environmental stress responsive promoter; and a step of cultivating the plant in the presence of environmental stress, the method comprising inducing expression of the gene located downstream of the environmental stress responsive promoter in a tissue-specific manner. | 11-12-2009 |
| 20090280563 | METHOD FOR PRODUCTION OF ANTIGEN-SPECIFIC HYBRIDOMA USING ARTIFICIAL LYMPH NODE WITH GOOD EFFICIENCY - Provided herein is a method for efficiently producing a hybridoma producing a specific antibody using an artificial lymph node. | 11-12-2009 |
| 20090275728 | COMPOUND HAVING HISTONE DEACETYLASE-INHIBITING ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING THE COMPOUND AS AN ACTIVE INGREDIENT - A novel compound having histone deacetylase-inhibiting activity which is a cyclic tetrapeptide derivative represented by the general formula (1) given below and a pharmaceutical composition comprising such compound as an active ingredient. (In the formula, the cyclic tetrapeptide moiety has a known structure; R | 11-05-2009 |
| 20090275067 | METHOD OF ACQUIRING HEPATIC OVAL CELLS - Provided are a method of isolating and identifying hepatic oval cells from the liver, and a method of single cell culture of hepatic oval cells. A method of separating and/or acquiring hepatic oval cells from a mammal, comprising a step for examining the expression of CD133, CD45 and Ter119. Particularly, hepatic oval cells that exhibit the pattern of CD133 | 11-05-2009 |
| 20090275017 | Novel Nucleoside or Nucleotide Derivative and Use Thereof - The object of the present invention is to provide a nucleoside or nucleotide having a 5-substituted-2-oxo(1H)pyridin-3-yl group as a base, as well as a method using the same. | 11-05-2009 |
| 20090273789 | Interferometer - A double-biprism electron interferometer is an optical system which dramatically increases the degree of freedom of a conventional one-stage electron interferometer. The double biprism interferometer, however, is the same as the optical system of the single electron biprism in terms of the one-dimensional shape of an electron hologram formed by filament electrodes, the direction of an interference area, and the azimuth of the interference fringes. In other words, the longitudinal direction of the interference area is determined corresponding to the direction of the filament electrodes, and the azimuth of the interference fringes only coincides with and is in parallel with the longitudinal direction of the interference area. An interferometer according to the present invention has upper-stage and lower-stage electron biprisms, and operates with an azimuth angle Φ between filament electrodes of the upper-stage and lower-stage electron biprisms to arbitrarily control an interference area and an azimuth θ of the interference fringes formed therein. | 11-05-2009 |
| 20090264604 | Metallocene Complex and Polymerization Catalyst Composition Containing the Same - Disclosed are a metallocene complex represented by the general formula (I), (II) or (III), and a polymerization catalyst composition containing such a metallocene complex. In the formulae (I), (II) and (III), M represents a lanthanoid element, scandium or yttrium; Cp | 10-22-2009 |
| 20090263428 | ARTIFICIAL LYMPH NODE FOR TREATING CANCER - Provided is an artificial lymph node that is persistently effective in cancer treatment in vivo. | 10-22-2009 |
| 20090251767 | METHOD AND APPARATUS FOR GENERATING TERAHERTZ WAVE - A method and an apparatus for generating a terahertz wave, wherein one end face | 10-08-2009 |
| 20090242381 | PHOTOREDUCTION PROCESSING METHOD OF THREE-DIMENSIONAL METAL NANOSTRUCTURE - In a method of producing a metal structure by photoreducing metal ion, a substance capable of suppressing growth of metal crystal is added to a medium in which metal ion is dispersed to prevent growth of the metal crystal produced by photoreduction of the metal ion, thereby processing resolution of a metal structure formed of the metal crystal is improved | 10-01-2009 |
| 20090240034 | METHOD FOR PRODUCING PEPTIDE THIOESTER - It is an object of the present invention to provide a novel method for producing a peptide thioester. In the present invention, general peptide synthesis is performed on a solid-phase resin, carboxylic acid obtained after cutout is allowed to react with p-toluenesulfonyl isocyanate, and then the reaction product is alkylated, and is reacted with thiol. Thus, peptide thioester is simply synthesized under mild conditions. | 09-24-2009 |
| 20090233323 | METHOD FOR ANALYSIS OF NKT CELL FUNCTION - The present invention provides a superior method of functional analysis of NKT cells, which enables function analysis of low frequency NKT cells, is independent of the function of autologous APCs, and can avoid an influence of secondary factors and the like. More specifically, the present invention provides a method of functional analysis of human NKT cells including (a) cocultivating a mononuclear cell derived from human peripheral blood with a CD1d-expressing antigen presenting cell derived from a heterologous animal, and (b) evaluating the functionality of NKT cells with the number of NKT cells and/or a substance specific to functional NKT cells as an index; a reagent for analysis of human NKT cells containing a CD1d-expressing antigen presenting cell derived from a heterologous animal; a kit containing (a) a CD1d-expressing antigen presenting cell derived from a heterologous animal, and (b) at least one reagent selected from the group consisting of a reagent for selection of human mononuclear cell, a reagent for measurement of the number of human NKT cells and a reagent for measurement of a substance specific to human functional NKT cells; and the like. | 09-17-2009 |
| 20090233290 | Mutant SepRS, and method for site-specific introduction of phosphoserine into protein using the same - A mutant SepRS which is suitable for a site-specific introduction of phosphoserine into a protein is prepared by analyzing the structure and functions of a phosphoseryl-tRNA synthetase (SepRS) derived from an archaebacterium. A mutant SepRS composed of an amino acid sequence depicted in SEQ ID NO:2, in which any one or more of glutamic acids at position-418 and position-420 and threonine at position-423 are substituted with other amino acid, and having enhanced binding affinity with a suppressor tRNA as compared with a wild type phosphoseryl-tRNA synthetase (SepRS) composed of an amino acid sequence depicted in SEQ ID NO:2 is provided. | 09-17-2009 |
| 20090233281 | DIAGNOSTIC MARKER FOR ALLERGY - The present invention provides a test system that specifically detects allergy, a test system that highly sensitively reflects aggravation of allergy and the like. | 09-17-2009 |
| 20090222953 | MUTATED PLANT AND METHOD FOR PRODUCTION THEREOF - According to the present invention, a novel mutated plant is provided based on findings obtained by analyzing the function of a functionally unknown gene having a CPC-like Myb sequence. | 09-03-2009 |
| 20090221516 | NOVEL GLYCOLIPID AND USE THEREOF - The present invention provide a compound represented by the following formula (1) | 09-03-2009 |
| 20090215707 | COMPOUND HAVING CYCLIC STRUCTURE AND USE THEREOF - The present invention relates to a compound represented by the following formula (1′) | 08-27-2009 |
| 20090214596 | Nasal Vaccine - The present invention provides a nasal vaccine capable of intranasally inducing an effective immunity reaction. Specifically, the invention provides a nasal vaccine containing a compound having an NKT cell-activating action, particularly a compound represented by the formula (I): | 08-27-2009 |
| 20090212660 | ULTRASONIC MOTOR AND METHOD FOR MANUFACTURING ULTRASONIC MOTOR - [Purpose] The present invention relates to an ultrasonic motor having a stator which includes a piezoelectric element for moving a rotor in a prescribed direction by applying a predetermined ultrasonic voltage thereto, and the rotor which is fixed to the stator by a frictional force, and a method for manufacturing an ultrasonic motor, and it has for its purpose to attain decrease of dust appearance by enhancement of a wear resistance, a different hardness, or the like in such a way that a contact part of at least either of a stator and a rotor which constitute the ultrasonic motor is irradiated with ions. | 08-27-2009 |
| 20090203749 | AGENT FOR CONTROL OF DEGRANULATION REACTION AND CYTOKINE PRODUCTION - To provide an agent capable of controlling the degranulation reaction and/or cytokine production of mast cell and the like. The present invention provides an agent for controlling a degranulation reaction and an agent for controlling a cytokine production, comprising a substance capable of controlling an intracellular zinc ion concentration, particularly, a zinc ion, a zinc ion chelator, an agent for controlling the expression and/or function of a zinc ion-requiring protein, or an agent for controlling the expression and/or function of a zinc ion transporter, as an active ingredient. | 08-13-2009 |
| 20090181012 | METHOD FOR DETECTING REGULATORY T CELLS USING EXPRESSION OF FOLATE RECEPTOR 4 AS INDICATOR, METHOD FOR TREATING DISEASES USING THE DETECTION METHOD, PHARMACEUTICAL COMPOSITION FOR IMMUNOSTIMULATION, AND METHOD FOR TREATING DISEASES USING THE COMPOSTION - An object of the present invention is to provide a technique to distinguish between T | 07-16-2009 |
| 20090176211 | FLUORESCENT PROTEIN - It is an object of the present invention to provide a fluorescent protein, which allows an acceptor for fluorescence resonance energy transfer (FRET) to appear in a stimulating light-dependent manner, thereby enabling the marking of any given cell organelle, cells, or tissues, with multiple colors. The present invention provides a fluorescent protein which consists of a fused protein of a donor fluorescent protein and an acceptor fluorescent protein, wherein before irradiation with stimulating light, the donor protein is able to emit fluorescence as a result of irradiation of the donor protein with excitation light; and after irradiation with stimulating light, intramolecular FRET occurs between the donor fluorescent protein and the acceptor fluorescent protein as a result of irradiation of the donor protein with excitation light, and the acceptor protein is able to emit fluorescence, and wherein the fluorescence of the donor protein and the fluorescence of the acceptor protein have wavelengths that are different from each other. | 07-09-2009 |
| 20090174523 | THICK FILM RESISTOR - In a flat plate type thick film resistor, an insulation performance is improved by excluding the nonuniformity of potential distribution on a wiring plane, which is generated when electric current flows in a resistance wire. Simultaneously, generation of noise depending on potential distribution and variation of stray capacitance around a resistor is suppressed. When the resistance wire having a constant thickness and uniform resistivity, which is formed on an insulating substrate, is connected to a pair electrode conductors that face to each other, in the way that the resistance wire is repetitively bent to the alternate side in zigzags, a potential gradient on the wiring plane, which is generated when electric current flows in the resistance wire, is constant by properly selecting the line width, the bending angle, and the spacing between bending vertexes of a resistance wire. | 07-09-2009 |
| 20090170773 | NOVEL USE OF G-PROTEIN-CONJUGATED RECEPTOR AND LIGAND THEREOF - The present invention provides a screening method for a substance that alters the bindability of RAIG2 or RAIG3 and glucose or 1,5-anhydroglucitol, including using RAIG2 or RAIG3 and glucose or 1,5-anhydroglucitol, and a regulator of sugar/lipid metabolism, a regulator of pancreas/pituitary function, a regulator of insulin secretion/blood glucose and ACTH secretion, and a prophylactic/therapeutic agent for a disease involved by an abnormality thereof, containing an RAIG2 or RAIG3 agonist or antagonist. | 07-02-2009 |
| 20090170205 | METHOD OF MAINTENANCE AND EXPANSION OF HEMATOPOIETIC STEM CELLS - [Problem] Provided are a method of maintaining/expanding hematopoietic stem cells, a hematopoietic stem cell population obtained by the method, a hematopoietic function ameliorating agent based on administration of the hematopoietic stem cell population to a living organism, and the like. | 07-02-2009 |
| 20090170178 | Cell stimulating device and cell stimulating method - It is an object of the present invention to provide an electrical stimulating device for efficiently providing direct electrical stimulation to a large number of nerve cells in vitro without causing any injuries to such cells. The present invention provides a cell stimulating device which comprises: a first electrode serving as a positive or negative electrode that extends from one side of a culture vessel that is used for accommodating cultured cells to a point at which the first electrode is not in contact with the cultured cells or is in contact with the surfaces of the cultured cells; and a second electrode serving as a negative or positive electrode that extends from the other side of the culture vessel to a point at which the second electrode is not in contact with the cultured cells or is in contact with the surfaces of the cultured cells, wherein an electric field for stimulating cells is formed via the first electrode and the second electrode. | 07-02-2009 |
| 20090170073 | FLUORESCENT PROTEIN AND CHROMOPROTEIN - It is an object of the present invention to provide a novel fluorescent protein and a novel chromoprotein. The present invention provides a novel fluorescent protein derived from | 07-02-2009 |
| 20090162869 | MEMBRANE MOLECULE EXPRESSED SPECIFICALLY IN ACTIVATED PLASMACYTOID DENDRITIC CELL - It is an object of the present invention to identify a membrane molecule that is specifically expressed on activated plasmacytoid dendritic cells, for the purpose of preventing or improving affection or disease such as cancer, autoimmune disease, allergy, or infectious disease by regulating the functions of dendritic cells capable of integrating an immune system. The present invention provides a protein having any one of the following amino acid sequences: | 06-25-2009 |
| 20090155888 | FLUORESCENT PROTEIN - The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b); | 06-18-2009 |
| 20090155844 | METHOD OF SYNTHESIZING A SUPPRESSOR tRNA, DNA CONSTRUCT AND USE THEREOF FOR PRODUCING A NON-NATURAL AMINO ACID-INCORPORATED PROTEIN - There are provided a DNA construct comprising non-eukaryote-derived suppressor tRNA gene containing no internal promoter functioning in a eukaryotic cell, and a eukaryote-derived or bacteriophage-derived promoter linked at the 5′ end of the tRNA gene, a method for synthesizing a suppressor tRNA by using the DNA construct, and a process for producing a non-natural amino acid-incorporated protein by using the same. | 06-18-2009 |
| 20090155214 | NOVEL BACTERIA AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME - An object of the present invention is to provide a means for imparting resistance against pathogenic fungal, pathogenic bacterial, or pathogenic viral disease to agriculturally useful plants. The present invention relates to a bacterium belonging to the genus | 06-18-2009 |
| 20090139752 | ELECTRONIC DEVICE AND METHOD FOR PRODUCING ELECTRONIC DEVICE - Provided is a novel electronic device that comprises graphite, graphene or the like. | 06-04-2009 |
| 20090134119 | FILM-FORMING MATERIAL AND METHOD OF FORMING PATTERN - A film-forming material that is capable of forming, at a low temperature, a film having a high degree of etching resistance and a high etching selectivity ratio relative to an organic film, as well as a method of forming a pattern that uses the film-forming material. The film-forming material includes a metal compound (W) capable of generating a hydroxyl group upon hydrolysis, and a solvent (S) in which the metal compound is dissolved, wherein the solvent (S) includes a solvent (S1) with a boiling point of at least 155° C. that contains no functional groups that react with the metal compound (W). The method of forming a pattern includes the steps of: coating a pattern, which has been formed on top of an organic film of a laminate that includes a substrate and the organic film, using the above film-forming material, and then conducting etching of the organic film using the pattern as a mask. | 05-28-2009 |
| 20090120696 | DEFORMABLE SENSOR SYSTEM - To provide a deformable sensor system, which makes it possible to obtain a pressure distribution with a much higher accuracy, while reducing the number of electrodes. | 05-14-2009 |
| 20090117208 | AMINO ACID COMPOSITION AND SUPPLEMENTARY LIQUID CONTAINING THE SAME - An amino acid composition comprises alanine, arginine, aspartic acid, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine, and glutamine. The amino acid composition of the present invention has such an effect that it can improve the action of promoting the process wherein the body fat is converted into the energy required for the physical exercise during and/or after the anoxic motions performed under an extremely high load. | 05-07-2009 |
| 20090112850 | Bioitem Searcher, Bioitem Search Terminal, Bioitem Search Method, and Program - According to one aspect of the present invention, a bio-item searching apparatus searches for a target bio-item with a keyword input by a user. In the bio-item searching apparatus, the storage device stores a bio-item literature set having a literature in which the bio-item name is described for each of bio-items. The control device searches each of the bio-item literature sets with the keyword to acquire the number (Nh) of literatures including the keyword for each of the bio-items, selects the bio-item in which the number-of-literatures Nh is 1 or larger as a candidate bio-item, creates, for each of the candidate bio-items, a number-of-literatures table constituted by any one or both of a) the number-of-literatures Nh, and b) the number of literatures each not including the keyword and including the bio-item name (the number of literatures in the bio-item literature set of the bio-item—Nh), calculates a correlation score between the bio-item and the keyword based on statistical calculation by using the number-of-literatures table for each of the candidate bio-items, and outputs the candidate bio-items to the output device based on the correlation score. | 04-30-2009 |
| 20090087625 | METHOD FOR MANUFACTURING STRUCTURE, AND STRUCTURE - A method of producing a structure, including:
| 04-02-2009 |
| 20090084972 | Gas Electron Multiplier and Manufacturing Method for Gas Electron Multiplication Foil Used for Same as Well as Radiation Detector Using Gas Electron Multiplier - To attain objects to reduce the spread of electrons as compared with a conventional one without degrading the multiplication factor of electrons; to provide a large electron multiplication factor; and to improve positional resolution, there is provided a gas electron multiplier using interaction between radiation and gas through photoelectric effects including: a chamber filled with gas and a single gas electron multiplication foil arranged in the chamber wherein the gas electron multiplication foil is made of a plate-like multilayer body composed by having a plate-like insulation layer made of a macromolecular polymer material having a thickness of around 100 μm to 300 μm and flat metal layers overlaid on both surfaces of the insulation layer, and the plate-like multilayer body is provided with a through-hole structure. | 04-02-2009 |
| 20090075921 | Bone/joint disease sensitivity gene and use thereof - The present invention provides the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of calmodulin, the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of asporin, and a diagnostic method for genetic susceptibility to bone and joint diseases by detecting polymorphisms in the CALM1 gene and/or the asporin gene, and the like. | 03-19-2009 |
| 20090067028 | OPTICAL NEAR-FIELD DISTRIBUTION TRANSFER DEVICE - Long-distance transfer of a super-resolution near field can be performed with a wavelength condition of high degree of freedom. Not only an image in same size can be merely transferred, but also a magnified image can be transferred. Thus the processing technique of a near-field image is improved. Small rods are erected at predetermined spacing with one another on a two-dimensional plane. At least the exterior surface of each small rod is made of a predetermined material having a dielectric constant ∈ | 03-12-2009 |
| 20090061170 | ANISOTROPIC FILM AND METHOD OF MANUFACTURING ANISOTROPIC FILM - An anisotropic film is disclosed in which a line-shaped nanostructure is disposed inside a resin film. Also disclosed is a method of producing an anisotropic film that includes: forming a metal nanostructure on a substrate, forming a resin film that embeds the metal nanostructure, and detaching the resin film from the substrate, wherein the step of forming the metal nanostructure on the substrate includes: at least, forming a coating film on the surface of a template provided on the substrate, the coating film including a metal layer formed by electroless plating; and removing a portion or all of the template while retaining a portion or all of the coating film, or removing a portion of the coating film. Also disclosed is an anisotropic film produced using the method of producing an anisotropic film. | 03-05-2009 |
| 20090061028 | PESTICIDAL/OVICIDAL COMPOSITION AND PESTICIDAL/OVICIDAL METHOD - A pesticidal/ovicidal composition comprising: (a) 50-97.9 parts by mass of a triglyceride containing not less than 50% of oleic acid as a fatty acid component; (b) 0.1-20 parts by mass of a cationic surface active agent; and (c) 2-30 parts by mass of a glycerin derivative, and a pesticidal/ovicidal method using the same. The composition according to the invention has not only a pesticidal activity but also an ovicidal activity on crop pests, and provides a safe and high pesticidal/ovicidal effect. | 03-05-2009 |
| 20090057688 | OPTICAL SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREFOR - To provide an elemental technique for improving the emission intensity of deep ultraviolet light from a light emitting layer made of an AlGaInN-based material, in particular, an AlGaN-based material. First, an AlN layer is grown on a sapphire surface. The AlN layer is grown under a NH | 03-05-2009 |
| 20090057646 | OPTICAL SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME - Because of a large lattice mismatch between a sapphire substrate and a group III-V compound semiconductor, a good crystal is difficult to grow. A high-quality AlN buffer growth structure A on a sapphire substrate includes a sapphire (0001) substrate | 03-05-2009 |
| 20090054316 | AGENT FOR CONTROL OF FUNCTION OF ANTIGEN-PRESENTING CELL - The present invention provides an agent capable of controlling the function of antigen-presenting cell. The present invention provides an agent for controlling the function of antigen-presenting cell, comprising a substance capable of controlling an intracellular zinc ion concentration, particularly, a zinc ion, a zinc ion chelator, a substance for regulating the expression and/or function of a zinc ion-requiring protein, or a substance for regulating the expression and/or function of a zinc ion transporter, as an active ingredient. | 02-26-2009 |
| 20090053773 | Reaction Container and Dna Amplification Reaction Method - A linear recess is provided in a reverse side surface of a synthetic resin base plate | 02-26-2009 |
| 20090053735 | Vector expressing n-deacetylase/n-sulfotransferase 2 - An object of the present invention is to provide an expression vector that allows for stable production of N-deacetylase/N-sulfotransferase 2 in large amounts and a process for production of N-deacetylase/N-sulfotransferase 2 using the same. The present invention provides a recombinant baculovirus expression vector obtained by incorporating into baculovirus DNA, a DNA fragment having lobster L21 DNA, DNA encoding gp67 signal peptide and DNA encoding the 79th to 883rd amino acids of human N-deacetylase/N-sulfotransferase 2 in this order in the 5′ to 3′ direction. | 02-26-2009 |
| 20090042197 | METHOD FOR DETECTING AND AMPLIFYING NUCLEIC ACID - Problem to be Solved There is provided a method for detecting and/or amplifying a nucleic acid contained in a biological sample such as blood or cells conveniently, rapidly, and effectively. | 02-12-2009 |
| 20090040217 | METHOD AND PROGRAM FOR GENERATING BOUNDARY SURFACE INFORMATION - A method includes: an input step of inputting boundary surface information | 02-12-2009 |
| 20090039563 | METHOD OF FORMING FINE PATTERN - A method of fine-pattern formation in which in forming a pattern, a fine pattern formed in a mold can be transferred to a pattering material in a short time at a low temperature and low pressure and, after the transfer of the fine pattern to the patterning material, the fine pattern formed in the patterning material does not readily deform. The method for fine-pattern formation comprises: a first step in which a mold having a fine structure with recesses/protrusions is pressed against a pattering material comprising a polysilane; a second step in which the patterning material is irradiated with ultraviolet to photooxidize the patterning material; a third in which the pressing of the mold against the patterning material is relieved and the mold is drawn from the pattering material; and a fourth step in which that surface of the patterning material to which the fine pattern has been transferred is irradiated with an oxygen plasma to oxidize the surface. | 02-12-2009 |
| 20090030167 | POLYMERIZATION CATALYST COMPOSITION FOR POLYMERIZATION OF ISOPRENE COMPOUND - 3,4-isoprene-based polymer having high isotacticity can be produced by polymerizing an isoprene compound using a complex represented by the general formula (A) and a catalyst activator:
| 01-29-2009 |
| 20090029284 | PATTERN COATING MATERIAL AND PATTERN FORMING METHOD - There are provided a coating material which improves an etching resistance of a pattern in an etching process using a pattern formed on a substrate as a mask. | 01-29-2009 |
