| REPLIDYNE, INC. Patent applications |
| Patent application number | Title | Published |
| 20090163536 | METHODS AND COMPOUNDS FOR TREATMENT OF CLOSTRIDIUM BASED INFECTION - Methionyl tRNA synthetase inhibitors (MetRS) are provided for use in therapy as antibacterial agents in | 06-25-2009 |
| 20090092592 | Methionyl tRNA Synthetase Polynucleotides - The invention provides metS polypeptides and DNA (RNA) encoding metS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metS polypeptides to screen for antibacterial compounds. | 04-09-2009 |
| 20090054667 | Transition metal catalyzed cross-coupling of 1-halo-1-haloalkene compounds - Methods for introducing a 1-halo-1-haloalkene compound onto an aromatic or heteroaromatic ring are provided, including processes for the production of certain 1-halovinyl aryl or heteroaryl derivatives in which the 1-halovinyl group is either 1-fluoro or 1-chlorovinyl and the aromatic species phenyl or thiophene, the processes including coupling an arylmagnesium species with a dihalo olefin in the presence of a nickel or iron catalyst. | 02-26-2009 |
| 20080227808 | Substituted Phenylether-Thienopyridone Compounds With Antibacterial Activity - Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti- | 09-18-2008 |
| 20080207703 | Antibacterial heterocyclic ureas - The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same. | 08-28-2008 |