REGION MIDTJYLLAND Patent applications |
Patent application number | Title | Published |
20150369820 | NOVEL DISEASE-MARKER - The invention relates to the use of soluble CD206 as a general health/disease marker, and a specific marker for liver disorders, sepsis, and pneumonia. | 12-24-2015 |
20150031739 | PANOBINOSTAT FOR USE IN THE TREATMENT OF HIV-1 - The present invention relates to uses and methods involving Panobinostat and HIV-1. In particular relates the present invention to Panobinostat for use in the treatment of HIV-1 and especially latent HIV-1. This is done using a low dosage of Panobinostat which is highly effective in depleting the HIV-1 reservoir. | 01-29-2015 |
20150017093 | RADIOLABELED BILE ACIDS AND BILE ACID DERIVATIVES - The present invention relates in one aspect to radiolabeled compounds comprising the structure of Formula 1. The radiolabeled compounds are preferably bile acids or bile acid derivatives. Further aspects of the invention relates to use of the compounds comprising the structure of Formula 1 in imaging methods such as for example PET, imaging method using a compound comprising the structure of Formula 1, administering said compound to an individual and making a radiographic image of a region of interest from said individual. | 01-15-2015 |
20140249041 | Marker of Prostate Cancer - An SLC18A2 gene serves as a marker of prostate cancer. Methods are provided for diagnosing prostate cancer, predicting or prognosticating the disease outcome, predicting recurrence following surgery, and monitoring disease progression in an individual having prostate cancer. The methods relate to determining the methylation state of an SLC18A2 gene and/or determining the level of transcription or translation of the gene in a sample from the individual. Methods of treating prostate cancer are also provided. The invention also pertains to compositions and kits for use in the methods. | 09-04-2014 |
20140039320 | ULTRASONIC SYSTEM FOR ASSESSING TISSUE SUBSTANCE EXTRACTION - The present invention relates to an ultrasonic system for measuring a micro-vascular flow distribution of a tissue portion of a mammal comprising an ultrasonic transducer ( | 02-06-2014 |
20140018649 | SYSTEM FOR ASSESSING TISSUE SUBSTANCE EXTRACTION - The present invention relates to a system for measuring a micro-vascular flow distribution of a tissue portion of a mammal comprising means ( | 01-16-2014 |
20130266197 | METHOD FOR DELINEATION OF TISSUE LESIONS - The present invention relates to a method for estimating a measure of a penumbra size of a penumbra in biological tissue wherein first and second images obtained respectively by perfusion weighted imaging (PWI) and diffusion weighted imaging (DWI) are analyzed, and wherein the analysis of the first image includes application of a level set method, and the analysis of the second image includes application of a grayscale morphological operation. In a further embodiment of the invention, a connected component labeling algorithm maybe applied on any one of the first and second image. The invention further relates to a system, a computer program product and use of a corresponding method. | 10-10-2013 |
20130211543 | TISSUE SCAFFOLD WITH CONTROLLED DRUG RELEASE - A three-dimensional hybrid scaffold capable of supporting cell activities such as growth and differentiation, and capable of controlled release of active pharmaceutical ingredients, characterized in that the scaffold comprises a first and a second biocompatible material, said first material shaped as a framework forming one or more open networks of voids, said second material comprising an ion exchange material, said ion exchange material being loaded with one or more active pharmaceutical ingredients. | 08-15-2013 |
20130123326 | ALLOSTERIC BINDING COMPOUNDS - The present invention relates to allosteric binding compounds of formula (I), especially for the treatment of CNS disorders, together with pharmaceutical compositions and methods of treatment including these compounds. | 05-16-2013 |
20120171718 | Submerged Perfusion Bioreactor - A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel. | 07-05-2012 |
20120128739 | THREE-DIMENSIONAL NANOSTRUCTURED HYBRID SCAFFOLD AND MANUFACTURE THEREOF - A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold. The scaffold design can be understood as a hierarchically organised structure. At the micron to submicron length scale a top/down manufacturing approach is used to make a structure that will constitute the frame into which a bottom/up processing approach is applied to form an open porous scaffold with specific nano sized features. The advantage of this hierarchically organised design is that benefits can be drawn independently from both the micron and the nano sized structures, promoting specific cell activities and providing sufficient mechanical compliance. | 05-24-2012 |
20120040004 | TREATMENT OF RADIATION-INDUCED FIBROSIS - The present invention relates to treatment or prevention of radiation induced fibrosis using TNF-alpha antagonism. Preferably, TNF-alpha is antagonized by direct binding or by inhibition of synthesis. In a preferred embodiment, the invention comprises intraperitoneal administration of a chitosan-siRNA nanoparticle, wherein the siRNA is targeted to the mRNA encoding TNF-alpha. | 02-16-2012 |
20100105088 | METHOD FOR DIAGNOSING ATHEROSCLEROTIC PLAQUES BY MEASUREMENT OF CD36 - The present invention relates to diagnosis, classification and monitoring of atherosclerotic plaques in an individual using measurement of the concentration of CD36 in a body fluid and/or the plaque as such. The present invention also relates to diagnosing the burden of atherosclerotic plaques in an individual. Furthermore, the invention relates to a method for diagnosing stenosis caused by atherosclerotic plaques. Within the scope of the present invention are also methods for determining the treatment regime of an individual. Kits and oligonucleotides for use in the methods are claimed. | 04-29-2010 |
20100048713 | COMPOUNDS ACTING ON THE SEROTONIN TRANSPORTER - The invention relates to new chemical compounds acting on the serotonin transporter (SERT), and associated pharmaceutical compositions, methods for use as therapeutic agents, and methods of preparation thereof. In particular the new chemical compounds are useful for the treatment of a variety of central nervous system (CNS) disorders—for example anxiety, depression, epilepsy, obsessive-compulsive disorders, migraine, cognitive disorders, sleep disorders, feeding disorders, panic attacks, disorders related to withdrawl from drug abuse, schizophrenia, or the like, or in the treatment of gastrointestinal disorders such as irritable bowel syndrome. | 02-25-2010 |