REGENPRIME CO., LTD. Patent applications |
Patent application number | Title | Published |
20100255065 | METHOD FOR DIFFERENCIATING MESENCHYMAL STEM CELL AND CULTURING CHONDROCYTES USING ALGINATE COATED FIBRIN/HA COMPOSITE SCAFFOLD - The present invention relates to a method for differentiating mesenchymal stem cells and culturing chondrocytes using a fibrin/HA(hyaluronate) composite whose biocompatibility and durability are enhanced, and a therapeutic composition containing the fibrin/HA composite, and more particularly, to a method for culturing chondrocytes and differentiating mesenchymal stem cells into chondrocytes using an alginate-coated fibrin/HA composite gel and a composition for treating a cartilage disease and a composition for treating a disc disease using a fibrin/HA composite scaffold containing a fibrin degradation inhibitor. According to the present invention, disadvantages of the traditional fibrin/HA composite being reduced in size and easily degraded in a short time period during culture were overcome, so that cells can be cultured in a more stable environment. The treatment composition according to the present invention has superior biocompatibility and biodegradability and thus it can be used for effective treatment for cartilage diseases, and it can regenerate the nuclei pulposi of a new intervertebral disk unlike currently used surgical treatment of degenerative intervertebral disk disease, so that it is expected that fundamental treatment of disc diseases can be achieved. | 10-07-2010 |
20100204618 | ULTRASOUND EQUIPMENT FOR TREATING OF EDEMA AND USE THEREOF - The present invention relates to an ultrasound equipment for treating edema, and more particularly, to an ultrasound equipment to relieve symptoms of edema or repair cellular and tissue edemas by generating 20˜400 mW/cm | 08-12-2010 |
20100137203 | METHOD FOR PREPARING A CELL-DERIVED EXTRACELLULAR MATRIX MEMBRANE - The present invention relates to a method for preparing a cell-derived extracellular matrix membrane, more particularly, to a method for preparing a chondrocyte-derived ECM membrane, the method comprising the steps of forming a suitable thickness of ECM membrane by culturing chondrocytes derived from animal cartilage at a high concentration in vitro, and drying it after decellularization process. The cell-derived ECM membrane scaffold according to the present invention is composed of extracellular matrix secreted by chondrocytes so that the membrane has excellent biocompatibility as well as an immune-previlage effect specific to cartilage. Since the membrane also has a suitable compressive strength, it can be used to replace periosteum for cartilage regeneration or artificial collagen membrane and used as dura mater transplant material, a natural ECM membrane for treating skin loss, materials for cell transplantation and a growth factor delivery vehicle. | 06-03-2010 |