Protein Design Lab, Ltd.
|Protein Design Lab, Ltd. Patent applications|
|Patent application number||Title||Published|
|20140349880||NOVEL ANTIBIOTIC PREPARATION METHOD AND PLATFORM SYSTEM BASED ON SAME - Provided are a novel antibiotic preparation method and platform system based on the method, belonging to a novel drug development method. The method is based on a fixed structural formula: F—R, wherein F is an effect area, and R is an identification area. At the prior art level, the present invention can quickly develop a specific novel antibiotic for most pathogenic microorganisms or biological cells. Also provided is a platform for implementing the method, ensuring that the novel antibiotic is developed in an efficient streamlined process.||11-27-2014|
|20130066051||FUSION POLYPEPTIDE AGAINST EB VIRUS-INDUCED TUMOR AND COLICIN IA MUTANT - The present invention provides a fusion polypeptide against EB virus-induced tumor, which comprises an antibody or a mimetic antibody against EB virus and an ion channel forming colicin selected form E1, Ia, Ib, A, B, N and their mutants. The present invention also provides a colicin Ia mutant, which comprises mutations of G11A, H22G, A26G, V31L, and H40D. The present invention also provides a gene, vector, preparation method and use of the fusion polypeptide, and provides a gene and use of the mutant.||03-14-2013|
|20120202734||ANTIBIOTIC, ITS NUCLEOTIDE SEQUENCE, METHODS OF CONSTRUCTION AND USES THEREOF - The present invention belongs to field of biology and medicine, and especially relates to a novel antibiotic, its nucleotide sequence, methods of construction and uses thereof. A novel antibiotic, wherein the end of any peptide of the allosteric colicin is connected linearly to the end of peptide of the||08-09-2012|
|20120190826||NOVEL ANTIBIOTIC COMPRISING AN ANTIBODY MIMETIC, ITS PREPARATION METHODS AND USES THEREOF - The present invention belongs to field of biology and medicine, and especially relates to a novel antibiotic comprising an antibody mimetic antibody, its preparation methods and uses thereof. A novel antibiotic comprising a antibody mimetic covalently bonded to the carboxyl end of a colicin polypeptide or a channel-forming domain polypeptide of a colicin, wherein said colicin is selected from the group consisting of Colicin E1, Ia, Ib, A, B, N; wherein said antibody mimetic being yielded by fusing two complementarity determining regions (CDRs), V||07-26-2012|
Patent applications by Protein Design Lab, Ltd.